United States Cell & Gene Therapy - Focused Insights 2023-2028: Approval of Over 20 Cell Therapy and 31 Gene Therapy Launches in the Pipeline for 2024

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Jun 23, 2023, 11:00 ET

DUBLIN, June 23, 2023 /PRNewswire/ -- The "US Cell & Gene Therapy Market - Focused Insights 2023-2028" report has been added to ResearchAndMarkets.com's offering.

This report offers market size & forecast data for the cell & gene therapy market in the US. The report covers commercial cell & gene therapy products, such as conventional cell therapies, CAR-T cell therapies, gene therapies, cell-based immunotherapies, and oncolytic virus therapies. Cell therapies sourced from mesenchymal stem cells, cell-based immune modulation therapies, and cell/tissue-based products derived from patients' blood are also covered in the report. Tissue-engineered products and tissue grafts/scaffolds with synthetic mechanical structures are excluded from the report's scope. This report provides a comprehensive and current market scenario of the US cell & gene therapy market, including the US cell & gene therapy market size, anticipated market forecast, relevant market segmentations, and industry trends.

The study considers a detailed scenario of the present cell and gene therapy market and its market dynamics for 2023-2028 in the US. It covers a detailed overview of several market growth enablers, restraints, and trends. The report offers both the demand and supply aspects of the market. It profiles and examines leading companies and other prominent players operating in the market.

In recent years, growth in the cell and gene therapy market has fueled some high-profile mergers and acquisitions, including bluebird bio/BioMarin, Bristol-Myers Squibb/Celgene/Juno Therapeutics, Gilead Sciences/Kite, Novartis/AveXis and the CDMO CELLforCURE, Roche/Spark Therapeutics, and Smith & Nephew/Osiris Therapeutics. Over 20 cell therapy launches and as many as 31 gene therapy launches - including more than 29 Adeno-associated viruses (AAV) therapies - are projected to be approved by 2024.

KEY HIGHLIGHTS OF THE REPORT

The US cell and gene therapy market was valued at $3.22 billion in 2022 and is projected to reach $25.58 billion in 2028, with a compound annual growth rate (CAGR) of 41.25%, during the study period.
Among all commercial cell & gene therapies, Zolgensma is the first and only product to achieve the blockbuster drug tag. Zolgensma generated a revenue of $1.37 billion in 2022 and could reach around $5.00 billion by 2026.
Drug developers are prioritizing developing and commercializing CAR-T cell-based gene therapies. Globally, more than 1,000 clinical trials are being conducted on CAR T-cell therapies, of which at least 500 clinical trials are for cancer alone. Kymriah (Novartis), Yescarta (Gilead Sciences), Tecartus (Gilead Sciences), Breyanzi (Bristol Myers Squibb), Abecma (Bristol Myers Squibb), and Carvykti (Janssen Biotech / Legend Biotech) are the commercial CAR-T therapies available in the market.
In 2022, the US was the fastest-growing market with a high market share in North America. The market is driven by an increased target patient population, regulatory body support, and higher access to healthcare due to well-established healthcare infrastructure.
The Food and Drug Administration (FDA) has approved over twenty cell and gene therapy drugs. Still, the new product pipeline has approximately 365 investigational therapies, with more than half of these in Phase 2 clinical trials. Oncology and rare diseases remain the top areas targeted by gene therapies from preclinical through pre-registration.
Approximately 1,604 clinical trials are under investigation for various cell and gene therapies in the US. This increase could be because of increased funding for cell and gene therapy. The industry-sponsored trials are continued to dominate with a share of 51.81%.
Novartis, Gilead Sciences, Spark Therapeutics, Amgen, Orchard Therapeutics, Bristol-Myers Squibb, BioMarin, PTC Therapeutics, and Organogenesis are the leading players in the US cell and gene therapy market. The market offers tremendous growth opportunities for existing and future/emerging players because of a large pool of target patient populations with chronic diseases such as cancer, genetic and rare diseases, and other complex disorders.

Key Topics Covered:

CHAPTER - 1: Cell & Gene Therapy Market Overview

Executive Summary
Introduction
Key Findings
Key Developments

CHAPTER - 2: Cell & Gene Therapy Market Segmentation Data

US: Projected Revenue of Cell & Gene Therapy (2022-2028; $Billions)
Product type
Application type
End-user type

CHAPTER - 3: Cell & Gene Therapy Prospects & Opportunities

Cell & Gene Therapy Market Drivers
Cell & Gene Therapy Market Trends
Cell & Gene Therapy Market Constraints

CHAPTER - 4: Cell & Gene Therapy Industry Overview

Cell & Gene Therapy - Marketed Drugs Overview
Cell & Gene Therapy - Pipeline Drugs Overview
Cell & Gene Therapy - Competitive Landscape
Cell & Gene Therapy - Key Players
Cell & Gene Therapy - Key Company Profiles
Cell & Gene Therapy - Mergers & Acquisitions
Cell & Gene Therapy - Key Strategic Recommendations

CHAPTER - 5: Pricing and Reimbursement Scenario

Pricing, Reimbursement and Market Access
Contract Manufacturing Organizations (CMOs)

CHAPTER - 6: Appendix

Research Methodology
Abbreviations

Companies Mentioned

Novartis
Gilead Sciences
Amgen
Roche
bluebird bio
Legend Biotech
Bristol-Myers Squibb
UniQure
Ferring Pharmaceuticals
Organogenesis
Vericel Corp
Dendreon
Mallinckrodt
Enzyvant
Avita Medical
Fibrocell
4DMT
Abeona Therapeutics
Autolus Therapeutics
Candel Therapeutics
Castel Creek Biosciences
Cellectis
Evox Therapeutics
Freeline Therapeutics
Generation Bio
Gensight Biologics
Krystal Biotech
MeiraGTx
Pfizer
Gamida Cell
Iovance Biotherapeutics
Sarepta Therapeutics
PTC Therapeutics
Atara Bio
Adaptimmune
CRISPR Therapeutics
Carsgen Therapeutics
Orchard Therapeutics
Biomarin
StemCyte
Helixmith

For more information about this report visit https://www.researchandmarkets.com/r/ykk5vf

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