Thirty-Year National Study Shows Women Who Breastfeed Six Months or More Reduce Their Diabetes Risk by 50 Percent

OAKLAND, Calif., Jan. 16, 2018 /PRNewswire/ -- Breastfeeding for six months or longer cuts the risk of developing type 2 diabetes nearly in half for women throughout their childbearing years, according to new Kaiser Permanente research published Jan. 16 in JAMA Internal Medicine.

"We found a very strong association between breastfeeding duration and lower risk of developing diabetes, even after accounting for all possible confounding risk factors," said lead author Erica P. Gunderson, PhD, MS, MPH, senior research scientist with the Kaiser Permanente Division of Research.

Women who breastfed for six months or more across all births had a 47 percent reduction in their risk of developing type 2 diabetes compared to those who did not breastfeed at all. Women who breastfed for six months or less had a 25 percent reduction in diabetes risk.

Gunderson and colleagues analyzed data during the 30 years of follow up from the Coronary Artery Risk Development in Young Adults (or CARDIA) study, a national, multi-center investigation of cardiovascular disease risk factors that originally enrolled about 5,000 adults aged 18 to 30 in 1985 to 1986, including more than 1,000 members of Kaiser Permanente Northern California.

The new findings add to a growing body of evidence that breastfeeding has protective effects for both mothers and their offspring, including lowering a mother's risk of breast and ovarian cancer. The CARDIA findings are also consistent with those of the NIH-funded Study of Women, Infant Feeding and Type 2 Diabetes after GDM Pregnancy (SWIFT), also led by Gunderson, which includes routine biochemical screening for diabetes in women after gestational diabetes from the early postpartum period and years later.

The long-term benefits of breastfeeding on lower diabetes risk were similar for black women and white women, and women with and without gestational diabetes. Black women were three times as likely as white women to develop diabetes within the 30-year study, which is consistent with higher risk found by others. Black women enrolled in CARDIA were also less likely to breastfeed than white women.

"The incidence of diabetes decreased in a graded manner as breastfeeding duration increased, regardless of race, gestational diabetes, lifestyle behaviors, body size, and other metabolic risk factors measured before pregnancy, implying the possibility that the underlying mechanism may be biological," Gunderson said. Several plausible biological mechanisms are possible for the protective effects of breastfeeding, including the influence of lactation-associated hormones on the pancreatic cells that control blood insulin levels and thereby impact blood sugar.

Based on the strong evidence for the numerous health benefits of breastfeeding for mothers and babies, Kaiser Permanente provides strong support for all mothers who choose to breastfeed.

"We have known for a long time that breastfeeding has many benefits both for mothers and babies, however, previous evidence showed only weak effects on chronic disease in women," said Tracy Flanagan, MD, director of women's health for Kaiser Permanente Northern California. "Now we see much stronger protection from this new study showing that mothers who breastfeed for months after their delivery may be reducing their risk of developing type 2 diabetes by up to one half as they get older. This is yet another reason that doctors, nurses and hospitals, as well as policymakers, should support women and their families to breastfeed as long as possible."

This study included 1,238 black and white women who did not have diabetes when they enrolled in CARDIA, or prior to their subsequent pregnancies. Over the next 30 years, each woman had at least one live birth and was routinely screened for diabetes under the CARDIA protocol, which included diagnostic screening criteria for diabetes. Participants also reported lifestyle behaviors (such as diet and physical activity) and the total amount of time they breastfed their children.

"Unlike previous studies of breastfeeding, which relied on self-reporting of diabetes onset and began to follow older women later in life, we were able to follow women specifically during the childbearing period and screen them regularly for diabetes before and after pregnancies," Gunderson said. She and her colleagues were also able to account for pre-pregnancy metabolic risk, including obesity and fasting glucose and insulin, lifestyle behaviors, family history of diabetes and perinatal outcomes.

The current study was funded by the National Institute of Diabetes, Digestive and Kidney Diseases that was led by Gunderson. The Coronary Artery Risk Development in Young Adults Study (CARDIA) is funded by the National Heart, Lung, and Blood Institute.

In addition to Gunderson, co-authors of the study were Ying Lin, MS, Mike Sorel, MS, Stephen Sidney, MD, MPH, and Charles Quesenberry, Jr., PhD, of the Kaiser Permanente Division of Research; Cora Lewis, MD, MSPH, and James Shikany, DrPH, of the University of Alabama at Birmingham; and Myron Gross, PhD, and David Jacobs, Jr, PhD, of the University of Minnesota.

About the Kaiser Permanente Division of Research
The Kaiser Permanente Division of Research conducts, publishes and disseminates epidemiologic and health services research to improve the health and medical care of Kaiser Permanente members and society at large. It seeks to understand the determinants of illness and well-being, and to improve the quality and cost-effectiveness of health care. Currently, DOR's 550-plus staff is working on more than 350 epidemiological and health services research projects. For more information, visit divisionofresearch.kaiserpermanente.org; follow us @KPDOR; or check out our Research Spotlight blog.

About Kaiser Permanente
Kaiser Permanente is committed to helping shape the future of health care. We are recognized as one of America's leading health care providers and not-for-profit health plans. Founded in 1945, Kaiser Permanente has a mission to provide high-quality, affordable health care services and to improve the health of our members and the communities we serve. We currently serve 11.7 million members in eight states and the District of Columbia. Care for members and patients is focused on their total health and guided by their personal Permanente Medical Group physicians, specialists and team of caregivers. Our expert and caring medical teams are empowered and supported by industry-leading technology advances and tools for health promotion, disease prevention, state-of-the-art care delivery and world-class chronic disease management. Kaiser Permanente is dedicated to care innovations, clinical research, health education and the support of community health. For more information, go to: kp.org/share.

For more information, contact:
Heather Platisha, [email protected], 415-262-5992
Janet Byron, [email protected], 510-891-3115

SOURCE Kaiser Permanente

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