The opportunity within the DNA Encoded Library Market to grow at 16% CAGR till 2035, according to a market research report by Roots Analysis

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Sep 05, 2023, 12:30 ET

In recent years, there has been a growth in the use of DNA encoded libraries, driven by several technological advancements and the growing demand for effective techniques for screening of potential drug targets

LONDON, Sept. 5, 2023 /PRNewswire/ -- Roots Analysis has announced the addition of "DNA Encoded Library Market, 2023-2035" report to its list of offerings.

Owing to its access to the largest chemical space available in the market, DNA encoded chemical library platforms are a natural fit for big data analytics and modeling technologies offered by artificial intelligence and machine learning. As a result, some companies have been pursuing this opportunity by integrating artificial intelligence and machine learning in DNA encoded libraries, including Insitro, a leading player in machine learning for drug discovery, which acquired Haystack Sciences in 2020. Insitro made the acquisition to leverage Haystack Sciences DNA sequencing technology to enhance its machine learning based drug discovery capability. Additionally, Google Research also collaborated with X-Chem in 2020 to develop an effective method for finding biologically active molecules using physical and virtual screening. Further, in 2021, Relay Therapeutics acquired ZebiAI for USD 85 million upfront, allowing them to incorporate the machine learning based DNA encoded chemical library technology into their protein targeting platform, Dynamo.

To order this 275+ page report, which features 130+ figures and 145+ tables, please check our DNA Encoded Library Market Report

Key Market Insights

Presently, around 50 companies claim to offer DNA encoded libraries and affiliated services for drug discovery across different regions of the world; majority of the players are based in the US
Leveraging their expertise, stakeholders are offering DNA encoded libraries for a myriad of drug discovery services; around 70% of the companies provides different type of library screening services
Majority of the companies engaged in this field of research are based in the developed geographies; the market landscape is fragmented, featuring the presence of both small firms and established players
Stakeholders have adopted various business models to maximize the gain from DNA encoded libraries; a significant number of in-house players have started out-licensing their DNA encoded library platforms
In pursuit of building a competitive edge, stakeholders are actively upgrading their existing capabilities to enhance their respective service offerings and comply with the evolving industry benchmarks
The growing interest in this domain is evident from the rise in partnership activity; in fact, the maximum number of collaborations related to DNA encoded libraries were inked in 2021
Several investors, having realized the opportunity within this domain, have invested over USD 4 billion across various funding rounds in the past six years
More than 400 patents have been filed / granted by various stakeholders in order to protect the intellectual property generated within this field since 2005
Big pharma players have undertaken several initiatives, ranging from proprietary library development to strategic investments, to tap the lucrative opportunity in this rapidly growing market
With an objective to provide support to DNA encoded libraries focused companies / organization, several stakeholders are deploying diverse support services as well as ancillary tools
In the short term, the opportunity is likely to be driven by library platform licensing activity; this activity is likely to increase as the industry realizes the capability of DNA encoded libraries to discover high-value therapeutic leads
The market is expected to grow at an annualized rate of 16% between 2023-2035; the projected opportunity is anticipated to be well distributed across various market segments

For additional details, please check out our report on DNA Encoded Library Market

The financial opportunity within the DNA encoded library market has been analyzed across the following segments:

Application Area

Hit Generation / Identification
Hit to Lead
Hit Validation / Optimization
Other Application Areas

Therapeutic Area

Oncological Disorders
Immunological Disorders
Neurological Disorders
Respiratory Disorders
Dermatological Disorders
Cardiovascular Disorders
Infectious Diseases
Other Therapeutic Areas

End-user

Pharma / Biopharma Industry
Academic / Research Institute
Other End-users

Type of Payment Model Employed

Upfront Payment
Milestone Payment

Key Geographical Regions

North America
Europe
Asia-Pacific

The opinions and insights presented in this report were also influenced by discussions held with eminent stakeholders in this industry. The report features detailed transcripts of interviews held with the following industry stakeholders:

Nils Jakob Vest Hansen (Chief Executive Officer, Vipergen)
Thorsten Genski (Chief Executive Officer, Serengen)
Thomas Kodadek (Co-Founder, Deluge Biotechnologies) and Ofelia Utset (President, Deluge Biotechnologies)
Frank Moffatt (Director of Business Development, NovAliX)
Christos Tsiamantas (Senior Scientist, Orbit Discovery)

The research also includes detailed profiles of key players (listed below) that offer DNA encoded library platforms and services; each profile features a brief overview of the company, its financial information (if available), details on platform and service portfolio, recent developments and an informed future outlook.

AlphaMa
DICE Therapeutics
DyNAbind
HitGen
NovAliX
Vipergen
WuXi AppTec
X-Chem

Key Questions Answered

What is a DNA encoded library?
What is DNA encoded library screening?
How are DNA encoded libraries made?
How is information encoded in DNA?
How DNA encoded libraries are revolutionizing drug discovery?
What are the advantages of DNA encoded library?
How many companies are developing DNA encoded libraries?
Which type of business model is widely adopted by companies in DNA encoded library market?
What is the current landscape of patents filed for DNA encoded libraries?
Who are the key players in the DNA encoded library market?
What are the leading market segments in the global DNA encoded library market?
Which region captures the largest share in the DNA encoded library market?
What is the likely growth rate (CAGR) for DNA encoded library market?

Table of Contents

Preface
Executive Summary
Introduction
Market Landscape
Business Model Analysis
Company Competitiveness Analysis
Company Profiles
Partnerships and Collaborations
Global Event Analysis
Patent Analysis
Big Pharma Initiatives
Case Study: Companies / Organizations Supporting the Development of DNA Encoded
Libraries
Market Forecast and Opportunity Analysis
Concluding Remarks
Executive Insights
Appendix 1: Tabulated Data
Appendix 2: List of Companies and Organizations