Successful Results in Clinical Trials Playing Important Role in Advanced Development of Therapeutic Drug Treatments for Various Diseases and Conditions

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Sep 21, 2015, 08:40 ET

CORAL SPRINGS, Florida, September 21, 2015 /PRNewswire/ --

A series of encouraging clinical test trial results and the latest therapeutic advancements for drug therapies may be leading to the trend that the outlook for the biotech sector is still bright. Recent trending biotech companies in focus are Q BioMed Inc (OTC: QBIO), Aerie Pharmaceuticals, Inc. (NASDAQ: AERI), Can-Fite BioPharma Ltd. (NYSE: CANF), Inotek Pharmaceuticals Corp (NASDAQ: ITEK) and TapImmune, Inc. (OTC: TPIV).

Q BioMed Inc (OTC: QBIO), a biotechnology acceleration and development company is pleased to announce a Letter of Intent to in-license and ultimately acquire the assets of Mannin Research Inc. Mannin Research Inc, is a biotechnology company leading the development of a new class of vascular therapeutics. The drug development program at Mannin is led by Mannin's Chief Scientific Officer, Dr. Susan E. Quaggin, Chief of the Division of Nephrology and Director of the Feinberg Cardiovascular Research Institute at Northwestern University in Chicago.

Read the full QBIO Press Release at http://www.financialnewsmedia.com/profiles/qbio.html

Utilizing a proprietary research platform, only recently published (September 2014) in the Journal of Clinical Investigations, this technology is addressing the need for a new class of drugs to treat diseases such as Glaucoma and Cystic Kidney disease. Our primary target indication is for a first-in-class therapeutic eye-drop for the treatment of Glaucoma in adults and children. The global market for Glaucoma therapeutics is one of the largest segments of the $23 billion global ophthalmology market. There are 60 million people worldwide suffering from Glaucoma. It is projected that the total population suffering from Glaucoma will grow to 80 million by 2020 (W.H.O 2010). Our lead candidate, MAN-01, will address this market as a first-in-class drug that treats abnormal vessels within the eye, thereby treating Glaucoma at its root causes. There have been no new class drugs developed for Glaucoma for 20 years, since Pfizer introduced Xalatan (latanaprost).

In other recent biotech/biopharma news and developments of interest: Aerie Pharmaceuticals, Inc. (NASDAQ: AERI), a clinical-stage pharmaceutical company focused on the discovery, development and commercialization of first-in-class glaucoma therapies, last week reported the successful results of its second Phase 3 trial for Rhopressa™, a novel once-daily, triple-action eye drop being tested for its ability to lower intraocular pressure (IOP) in patients with glaucoma or ocular hypertension. The trial achieved its primary efficacy endpoint demonstrating non-inferiority of Rhopressa™ compared to timolol, the most widely used comparator.

Can-Fite BioPharma Ltd. (NYSE: CANF), a biotechnology company with a pipeline of proprietary small molecule drugs that address inflammatory and cancer diseases, announced last week the U.S. Food and Drug Administration (FDA) has granted the Company's drug candidate CF102 Fast Track designation as a second line treatment for hepatocellular carcinoma (HCC), the most common form of liver cancer. CF102 had already received the FDA's Orphan Drug designation. Can-Fite is currently conducting a Phase II study for this indication in the U.S., Europe and Israel. The randomized, double blind, placebo controlled study is expected to complete enrollment by the end of the first half of 2016 in 78 patients with Child-Pugh Class B cirrhosis who failed the only FDA approved drug on the market, Nexavar® (sorafenib). Patients are treated twice daily with 25 mg of oral CF102, which has been found to be the most efficacious dose in Can-Fite's earlier Phase I/II study resulting in the longest overall survival time, with excellent safety results.

Inotek Pharmaceuticals Corp (NASDAQ: ITEK)'s stock had its "overweight" rating restated by equities researchers at Piper Jaffray in a research report issued to clients and investors on Thursday, Analyst Ratings Network.com reports. They presently have a $29.00 price objective on the stock. Piper Jaffray's target price suggests a potential upside of 98.90% from the stock's previous close. Read the full article here (http://www.wkrb13.com/markets/789929/inotek-pharmaceuticals-corp-stock-rating-reaffirmed-by-piper-jaffray-itek/) Inotek Pharmaceuticals, a clinical-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapies for glaucoma.

TapImmune, Inc. (OTC: TPIV) Vaccine to be Studied in a $13.3 Million U.S. Department of Defense Grant to Mayo Clinic for Phase II Clinical Trial in Triple Negative Breast Cancer. This grant, commencing September 15, 2015, covered the costs for a 280 patient Phase II Clinical Trial of Folate Receptor Alpha Vaccine in patients with Triple Negative Breast Cancer. Award recipients are Keith L. Knutson. Ph.D., professor of Immunology at the Mayo Clinic Center for Immunology and Immune Therapies, and Edith A. Perez, M.D., deputy director at large for Mayo Clinic Cancer Center and the Serene M. and Frances C. Durling Professor of Medicine at Mayo Clinic College of Medicine, both at Mayo Clinic's Florida campus in Jacksonville.

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