Sigma-Aldrich Accelerates Analytical Research and Extends Benefits of Fused-Core Particle Technology to All HPLC Users with the Launch of New Ascentis Express 5 Micron Particle by Supelco

ST. LOUIS, July 25, 2012 /PRNewswire/ -- Sigma-Aldrich® Corporation (NASDAQ:SIAL) announced today its Supelco® brand launched the Ascentis® Express C18, 5 micron particle size column to improve speed and increase efficiencies in high purity liquid chomatography (HPLC) procedures. The new columns are based on innovative Fused-Core® particle technology, which enables the production of columns capable of achieving greater speed and efficiencies than conventional 5 micron particle columns. The Ascentis Express family provides scientists a premier choice for performance improvement on traditional HPLC systems and eliminates the concerns associated with smaller particle columns.

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The new columns deliver the speed and resolving power of conventional 3 micron particle columns, as well as provide greater ruggedness and a longer life cycle than columns using sub 2 micron particles. Operating back pressures of the new column family are comparable to columns using 5 micron particles, ensuring pressure limits are not exceeded in conventional HPLC instrumentation. The Ascentis Express line is scalable from ultra high purity liquid chromatography (UHPLC) to legacy HPLC systems.

"Supelco's latest extension to the Ascentis Express line allows scientists to boost the performance of legacy HPLC systems and effortlessly transfer methods amongst sites or contract research organizations (CRO) without incompatibility concerns," said Dr. Wayne Way, HPLC/GC Market Segment Manager, Supelco. "These columns are expected to be extremely beneficial for bioanalytical LC/MS as they excel at the high flow rates and high throughput demands of these methods.  Furthermore, the large particle format provides an extremely rugged HPLC column," concludes Dr. Way.

Available in introductory phases C18 and F5, the conversion of current methods is simple. Conventional HPLC users can simply "drop-in" the replacement column without changing column dimensions, flow rates or sample prep.

A new HPLC method transfer calculator 'App' has also been launched on the Sigma-Aldrich website at http://www.sigmaaldrich.com/hplccalculator. This App makes it easy to switch columns and change methods by calculating conditions for transfer of an isocratic or gradient method from one HPLC column to another. It also enables easy method scaling from microbore through preparative column dimensions, including time and solvent savings calculations. The App is available for iPad®, iPhone® and Android™ mobile devices.

Cautionary Statement: The foregoing release contains forward-looking statements that can be identified by terminology such as "are expected to" or similar expressions, or expressed or implied discussions regarding potential future revenues from products derived therefrom. You should not place undue reliance on these statements. There can be no guarantee that any of these products will achieve any particular levels of revenue in the future. Such forward-looking statements reflect the current views of management regarding future events, and involve known and unknown risks, uncertainties and other factors that may cause actual results to be materially different from any future results, performance or achievements expressed or implied by such statements.

About Supelco:  Supelco is a Sigma-Aldrich research brand that offers innovative technologies, chromatography consumables and services aimed at analytical chemistry. Supelco offers an extensive portfolio of research-proven analytical tools and solutions that are used in scientific research, quality control and manufacturing within the healthcare, food and beverage, environmental, chemical purification and energy markets.

About Sigma-Aldrich: Sigma-Aldrich is a leading Life Science and High Technology company whose biochemical and organic chemical products,  kits and services are used in scientific research, including genomic and proteomic research, biotechnology, pharmaceutical development, and as key components in pharmaceutical, diagnostic and other high technology manufacturing.  Sigma-Aldrich customers include over a million scientists and technologists in life science companies, university and government institutions, hospitals and in industry. The Company operates in 35 countries and has nearly 9,000 employees whose objective is to provide excellent service worldwide. Sigma-Aldrich is committed to accelerating our Customers' success through leadership in Life Science, High Technology and Service. For more information visit our award winning web site at http://www.sigma-aldrich.com.

Sigma-Aldrich and Supelco are trademarks of Sigma-Aldrich Co. LLC registered in the US and other countries.  Ascentis is a registered trademark of Sigma-Aldrich Co. LLC. Fused-Core is a registered trademark of Advanced Materials Technology, Inc. Supelco brand products are sold through Sigma-Aldrich, Inc. iPad and iPhone are trademarks of Apple, Inc., registered in the US and other countries. Android is a trademark of Google, Inc.

SOURCE Sigma-Aldrich Corporation

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