Patient-Centered Outcomes Research Institute to Invest Up to $68 Million to Develop a National Patient-Centered Clinical Research Network

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Patient-Centered Outcomes Research Institute

Apr 23, 2013, 09:00 ET

Funding aims to improve capacity to conduct comparative effectiveness research

WASHINGTON, April 23, 2013 /PRNewswire-USNewswire/ -- The Patient-Centered Outcomes Research Institute (PCORI) issued two funding announcements today for up to $68 million to support development of a National Patient-Centered Clinical Research Network.

The announcements fall under one of PCORI's five National Priorities for Research, "Accelerating Patient-Centered and Methodological Research," and aim to improve the nation's capacity to efficiently conduct comparative clinical effectiveness research (CER).

"CER can play a significant role in improving the volume and usability of information available to patients, caregivers, clinicians, and other key stakeholders across the healthcare community," said PCORI Executive Director Joe Selby, MD, MPH. "A national data-rich infrastructure that advances high-quality, efficient CER will benefit all Americans."

The two linked cooperative agreement funding announcements, unveiled today at a PCORI roundtable discussion on building a national data infrastructure to advance CER, will support Clinical Data Research Networks (CDRNs) and Patient-Powered Research Networks (PPRNs). Together, PCORI believes, these initiatives can unite patients, researchers and healthcare systems to support efficient, effective observational and interventional studies with active participation from broad patient populations.

PCORI will fund up to $56 million to support up to eight new or existing CDRNs that will develop the capacity to conduct randomized comparative effectiveness studies using data from clinical practice in large, defined populations. PCORI also will fund up to $12 million to support up to 18 new or existing PPRNs and their progression toward a reusable, scalable, and sustainable research network.

Two innovative features of this initiative are PCORI's expectation that health systems, clinicians and patients will play key roles in governing the direction and uses of the networks that this funding will support, and that the interests of patients will be central to decision-making about the network's structure, function, and uses.

Over time, PCORI expects the PPRNs and CDRNs to become more integrated as a result of activating and engaging patients within multiple healthcare systems and obtaining richer clinical data on members who receive their care outside of participating systems. A funding announcement to support a Coordinating Center – which will provide management support for collaborative projects, technical resources, meeting support, and program evaluation – will be released later this spring.

"We see this initiative, unlike many past efforts, as an opportunity to bring together the many sectors within healthcare that can be both sources and users of the types of rich clinical data that, if carefully and appropriately gathered and used, can significantly advance patient-centered CER," Selby said. "We know that this won't be easy, but we believe the results will be more than worth the effort."

Today's funding announcements constitute Phase One of the network's development. Subsequent phases and funding announcements will be informed by the results of Phase One.

Complete announcements are available in the Funding Opportunities section of PCORI's website, www.pcori.org. Required letters of intent (LOI) from applicants are due June 19 and applications are due September 27.

About PCORI
The Patient-Centered Outcomes Research Institute (PCORI) is an independent, non-profit organization authorized by Congress in 2010. Its mission is to fund research that will provide patients, their caregivers and clinicians with the evidence-based information needed to make better-informed health care decisions. PCORI is committed to continuously seeking input from a broad range of stakeholders to guide its work. More information is available at www.pcori.org.

SOURCE Patient-Centered Outcomes Research Institute