Monoclonal Antibodies: A Transformative Force in Biopharmaceuticals, Driving Growth in Antibody Discovery Services and Platforms

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Oct 19, 2023, 13:00 ET

DUBLIN, Oct. 19, 2023 /PRNewswire/ -- The "Antibody Discovery Market: Focus on Services and Platforms - Distribution by Type of Service Offered, Antibody Discovery Method, Type of Antibody Generated, Nature of Antibody Generated, Therapeutic Areas and Key Geographies: Industry Trends and Global Forecasts, 2023-2035" report has been added to ResearchAndMarkets.com's offering.

The global antibody discovery services and platforms market is poised for significant growth, with a projected value of over $1.6 billion in 2023 and a forecasted Compound Annual Growth Rate (CAGR) of 12.0% during the coming years. The market is driven by pharmaceutical companies' increasing reliance on outsourcing antibody discovery processes and the growing demand for targeted therapies.

Streamlining Drug Development with Outsourcing

The traditional drug development process is lengthy, spanning 10-15 years and involving investments of over $2 billion. Despite these efforts and investments, more than 90% of drug candidates fail in clinical trials. To streamline drug development, reduce timelines, and mitigate financial risks associated with failed trials, pharmaceutical companies are increasingly outsourcing their discovery-stage operations to specialized contract research organizations (CROs). Outsourcing allows companies to optimize resource utilization, save costs, and tap into a global network of scientific talent, ultimately enhancing the efficiency and success rate of bringing novel antibody-based therapeutics to market.

Evolution of Monoclonal Antibodies

Since the approval of the first monoclonal antibody-based therapy, Orthoclone OKT3, in 1986, monoclonal antibodies have become a versatile class of biopharmaceuticals. These antibodies have seen significant advancements in engineering, format diversification, and discovery methods. Over 160 monoclonal antibodies have been approved worldwide for the treatment of diseases such as cancer, chronic inflammatory diseases, infectious diseases, and cardiovascular diseases. Recent approvals include ELREXFIOT, TALVEYT, Rystiggo, COLUMVI, and EPKINLYT. Due to the complexities associated with discovering such antibodies, many firms are licensing and utilizing specialized antibody discovery platforms and technologies, driving the growth of the antibody discovery services and platforms market.

Market Drivers: Biotech Advancements and Increasing Demand

Key drivers of the global antibody discovery services and platforms market include recent advancements in biotechnology, a growing demand for targeted therapies, rising prevalence of chronic diseases, increased R&D expenditure in the pharmaceutical industry, and a growing trend of outsourcing antibody discovery. Collaborations between academic institutions and antibody discovery companies further contribute to market growth.

Market Size and Segments

The global market size for antibody discovery services and platforms is projected to grow at an annualized CAGR of 11.0% during the forecast period. The hit generation segment holds the largest market share, driven by its significance in R&D expenditure. In terms of the antibody discovery method, the hybridoma method is dominant, thanks to its capability to create immortalized cell lines for continuous antibody manufacturing.

Regional Analysis: North America Leads

North America currently captures nearly 40% of the market, driven by a rising interest in advanced antibody discovery platforms and increased outsourcing in the pharmaceutical industry. North America is anticipated to grow at a CAGR of 12% during the forecast period.

Key Players and Recent Developments

Key players in the antibody discovery services and platforms market include Ablexis, Antibody Solutions, ChemPartner, GenScript, Genmab, Harbour BioMed, ImmunoPrecise, Mabsilico, and more. Recent developments in the field include the launch of transgenic mouse-based antibody discovery platforms and initiatives to support the discovery of bispecific antibody formats.

Recent Developments:

In June 2023, AbTherx announced the launch of its transgenic mouse-based antibody discovery platform, AtlasT Mice.
In June 2023, Sanyou Biopharmaceuticals, a China-based company, launched its Sanyou Super Trillion Common Light Chain Antibody Discovery Platform, which supports the discovery of bispecific antibody formats.
In January 2023, IASO Biotherapeutics raised USD 75 million in a venture series C round, highlighting the increasing funding activity in the antibody drug discovery service and platform domain.
In March 2023, Twist Bioscience announced the launch of its antibody discovery services under the Twist Biopharma Solutions subsidiary after acquiring Abveris, an antibody discovery CRO, in 2022.

Key Topics Covered:

1. PREFACE

2. RESEARCH METHODOLOGY

3. ECONOMIC AND OTHER PROJECT SPECIFIC CONSIDERATIONS

4. EXECUTIVE SUMMARY

5. INTRODUCTION

6. ANTIBODY DISCOVERY: PROCESS AND METHODS

7. ANTIBODY DISCOVERY SERVICE PROVIDERS: MARKET LANDSCAPE

8. COMPANY COMPETITIVENESS ANALYSIS

9. COMPANY PROFILES: ANTIBODY DISCOVERY SERVICE PROVIDERS

10. ANTIBODY DISCOVERY TECHNOLOGIES: MARKET LANDSCAPE

11. TECHNOLOGY COMPETITIVENESS ANALYSIS

12. COMPANY PROFILES: ANTIBODY DISCOVERY PLATFORM PROVIDERS

13. PARTNERSHIPS AND COLLABORATIONS

14. FUNDING AND INVESTMENT ANALYSIS

15. MARKET IMPACT ANALYSIS: DRIVERS, RESTRAINTS, OPPORTUNITIES AND CHALLENGES

16. GLOBAL ANTIBODY DISCOVERY SERVICES MARKET

17. ANTIBODY DISCOVERY SERVICES MARKET, BY TYPE OF SERVICE OFFERED

18. ANTIBODY DISCOVERY SERVICES MARKET, BY TYPE OF ANTIBODY DISCOVERY METHOD

19. ANTIBODY DISCOVERY SERVICES MARKET, BY NATURE OF ANTIBODY DISCOVERED

20. ANTIBODY DISCOVERY SERVICES MARKET, BY TYPE OF THERAPEUTIC AREAS

21. ANTIBODY DISCOVERY SERVICES MARKET, BY KEY GEOGRAPHIES

22. GLOBAL ANTIBODY DISCOVERY TECHNOLOGIES MARKET

23. ANTIBODY DISCOVERY TECHNOLOGIES MARKET, BY TYPE OF ANTIBODY DISCOVERED

24. ANTIBODY DISCOVERY TECHNOLOGIES MARKET, BY KEY GEOGRAPHIES

25. LICENSING DEAL STRUCTURE

26. SWOT ANALYSIS: ANTIBODY HUMANIZATION SERVICE PROVIDERS

27. CASE IN POINT: DRUG DISCOVERY PROCESSES OF TOP SELLING ANTIBODIES

28. FUTURE GROWTH OPPORTUNITIES IN ANTIBODY DISCOVERY

29. CONCLUSION

30. EXECUTIVE INSIGHTS

31. APPENDIX 1: TABULATED DATA

32. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATION

Companies Mentioned

2BScientific
3SBio
AAT Bioquest
Ab Initio Biotherapeutics
Ab Studio
ABBA Therapeutics
AbBioSci
Abbiotec
AbbVie
Abcalis
Abcam
AbCellera
Abcentra (formerly CardioVax)
Abcepta
AbCheck
Abclonal
Abcore
ABDYS
Abeome
Abexxa Biologics
ABGENEX
AbGenics Life Sciences
Abilita Bio
ABL Bio
Ablexis
Ablynx
Abnova
Abpro
AbSano
Absci
Absea Biotechnology
Absolute Antibody
Abterra Biosciences
AbTherx
AbTis
Abveris (Acquired by Twist Bioscience)
AbVision
Abwiz Bio
Abzena
Abzyme Therapeutics
AC Immune
Acceleron Pharma
Accurus Biosciences
AceMab
Achaogen
Aclys Bio
ACROBiosystems
ACYTE Biotech
Adagene
Adaptate Biotherapeutics
ADC Therapeutics
Adcentrx Therapeutics
Adimab
AdipoGen Life Sciences
Administration for Strategic Preparedness and Response (ASPR)
Aduro Biotech
AffinityImmuno
AFSBio
Aganitha
Agency for Science, Technology and Research
Agenus
Agro-Bio
AIMM Therapeutics
Aimmune Therapeutics
Akeagen
Akeso
Akeso Biopharma
Alacrita
Alamar Biosciences
Aldevron
Alector
Alexion
AlivaMab Discovery Services
Alligator Bioscience
Allogene Therapeutics
Alloy Therapeutics
Almirall
AlpalifeBio
ALSA Ventures
Alvaxa Biosciences (Acquired by Sensei Biotherapeutics)
ALX Oncology
Alytas Therapeutics
Amerigo Scientific
Amgen
AMSBIO
Analytics Engine
AnaptysBio
Angios
Annoron Biotechnology
Antengene
Antibodies Incorporated
Antibodies-online
Antibody Analytics
Antibody Design Labs
Antibody Production Services (A division of Life Science Group)
Antibody Solutions
Antiverse
AP Biosciences
Apexigen
APITBIO
Applied Biological Materials
Applied StemCell
AprilBio
Aptevo Therapeutics
Aragen Life Sciences
Aravive
Arctoris
Arcus Biosciences
argenx
Aridis Pharmaceuticals
aRNAy Sciences
Aro Biotherapeutics
Aronora
Arsanis
Artizan Biosciences
Arvinas
ARVYS Proteins
AskGene Pharma
Astellas
AstraZeneca
aTen Therapeutics
Atlantis Bioscience
Atlas Venture
Atreca
ATUM
Aureka
Aurigene Pharmaceutical Services
Autolus Therapeutics
Automated Lab Solutions
AvantGen
Aviva Systems Biology
AxioMx
Axxora
Bayer
BBI Group
BBI Solutions
Beckman Coulter
BeiGene
BenevolentAI
Berkeley Lights
Betta Pharmaceuticals
Bhami's Research Laboratories
Bhat Bio-tech India
Big Cypress Acquisition
BigHat Biosciences
Bill & Melinda Gates Foundation
Bill & Melinda Gates Medical Research Institute
Bio Bench
BioArctic
BioAtla
BioBench Solutions
Biochem Pharma
BioClue (Acquired by ImmunoPrecise Antibodies)
Bio-Connect
Biocure Technology
Biocytogen
BioD
BioDuro-Sundia
Biogen
BioHub International Trade
Bioinborn Scientific
Biointron
BioInvent
BioKey (Acquired by ImmunoPrecise Antibodies)
Biologics International
Biomolecular Discovery Services
BioNTech
Bioqube Ventures
Bio-Rad Laboratories
Biosion
BioStrand (Acquired by ImmunoPrecise Antibodies)
Biosynth
Biotalys
Bio-Techne
Biotecnol
BIOTEM
BioTeZ
Biotheus
BioTickle
BioVision
BioXpress Therapeutics
Bird Rock Bio
Blue Sky BioServices (Acquired by LakePharma)
BlueBird Bio
Bluejay Therapeutics
Boan Biotech
Boehringer Ingelheim
Bolt Biotherapeutics
Boster Biological Technology
Bristol Myers Squibb
Broteio Pharma
CALIXAR
Cambridge Research Biochemicals
CANbridge Pharmaceuticals
Cancer Research UK
Cantargia
Capra Science
Capralogics
Caris Life Sciences
Carterra
CASI Pharmaceuticals
Catalent Biologics
Cayman Chemical
CD ComputaBio
CDI Laboratories
Celexion
Celgene
Cell Signaling Technology
Celltrion
Celros Biotech
Celsius Therapeutics
Centre for Applied Medical Research
Centers for Disease Control and Prevention
Charles River
ChemBio Discovery Solutions
ChemPartner
Cherry Biolabs
Chia Tai Tianqing Pharmaceutical
Chiome Bioscience
Chipscreen Biosciences
ChromoTek
Chugai Pharmabody Research
Chugai Pharmaceutical
Cidara Therapeutics
Cilag
Citryll
City of Hope
Cizzle Biotechnology
Clayton Biotechnologies
Click Chemistry Tools
Clinica Universidad de Navarra
CliniSciences
Columbia University Irving Medical Center
Compass Therapeutics
Context Therapeutics
Coronavirus Immunotherapy Consortium
Corvidia Therapeutics
Cosmo Bio
CP Qingdao
Creative Bioarray
Creative Biolabs
Creative Biostructure
Creative Diagnostics
Crescendo Biologics
Crystal Bioscience
CSL Behring
Cstone Pharmaceuticals
CureVac
Curia
CUSABIO
Cyclogenix
Cygnus Technologies
DAAN Biotherapeutics
Daiichi Sankyo
Dako
Dana-Farber Cancer Institute
Danaher
DaTaMabs
DBA Italia
Deerfield Discovery and Development
Denali Therapeutics
DetaiBio
Diagnostic BioSystems
Diatheva
Digital Proteomics
Dingkang Biology
discoveric bio
Distributed Bio
DJS Antibodies
Dragonfly Therapeutics
E2DG
Eisai
Elabscience
Eli Lilly and Company
Elpis Biopharmaceuticals
Emergent BioSolutions
Empirico
e-nnovation Life Sciences
ENPICOM
Enthera
Entos Pharmaceuticals
Envigo
EpimAb Biotherapeutics
EQRx
Erasmus MC
Ethris
Eureka Therapeutics
Eurofins Discovery
Everest Medicines
Evitria
Evotec
EVQLV
Exelixis
ExeVir Bio
Exiris
exonbio
Exscientia
Faculta (Acquired by Prosci)
FairJourney Biologics
Faron Pharmaceuticals
Ferring Pharmaceuticals
FibroGen
Five Prime Therapeutics
Fluoroprobes
Forty Seven
Foundery Innovations
Fred Hutchinson Cancer Center
Frederick National Laboratory for Cancer Research
French Institute of Health and Medical Research
Frugi Biotechnology
Funakoshi
Fusion Antibodies
Fusion Pharmaceuticals
G&P Biosciences
G.CLIPS BIOTECH
Gator Bio
Genagon Therapeutics
Gene Techno Science
GeneBeyond
Genedata
GeneFrontier
GENEWIZ (Acquired by Azenta Life Sciences)
GeneX India Bioscience
Genmab
Genome Institute of Singapore
Genor Biopharma
GenoSafe
Genovac
GenScript
Genuv
Gen-Y Biologics
GigaGen
Gilead Sciences
Gladstone Institutes
Glenmark Pharmaceuticals
Glythera
Gmax Biopharm
Government of British Columbia
Government of Canada
Green Mountain Antibodies
Grenoble Hospital
GSK
Gustave Roussy
GV20 Therapeutics
HaemaLogiX
Hangzhou Qiantang River Electric
Harbour Antibodies
Harbour BioMed
Harpoon Therapeutics
HD Biosciences
Helix BioPharma
Jiangsu Hengrui Pharmaceuticals
Henlix Biotech
Heptares Therapeutics
HI-Bio
HiFiBiO Therapeutics
Himalaya Therapeutics
H-Immune Therapeutics (Acquired by HiFiBiO Therapeutics)
HJB
Holzel Diagnostika Handels
Horizon Discovery
Hualan Genetic Engineering
Hubrecht Institute
Humanigen
Hummingbird Bioscience
I&L Biosystems
i2 Pharmaceuticals
IAMA France
IASO Biotherapeutics
Ibex Biosciences
iBio
Icagen
Icosagen
IGEM Therapeutics
IgGenix
IGM Biosciences
I-Mab Biopharma
iMetabolic Biopharma
Immatics Biotechnologies
Immorna
Immune Biosolutions
Immune Pharmaceuticals
Immunitas Therapeutics
immunitoAI
Immunochem
ImmunoChina Pharmaceuticals
ImmunoGenes
Immunome
Immunomic Therapeutics
ImmunoPrecise Antibodies
ImmunoQure
Immusmol
Immutep
In-Cell-Art
Incyte
Indivumed
InflaRx
Inhibrx
Innate Pharma
InnoBation Bio
Innovagen
Innovative Targeting Solutions
Innovent
Inotiv
InstaDeep
Institute for Research in Biomedicine
Intarcia Therapeutics (Acquired by i2o Therapeutics)
Integral Molecular
Integrated DNA Technologies
International Livestock Research Institute
Invenra
Invetx
IONTAS
IRBM
Isogenica
Italian National Institute of Health
ITBMed
iTeos Therapeutics
Janssen
Jazz Pharmaceuticals
Johnson & Johnson Innovation
Jotbody
Jounce Therapeutics
Juno Therapeutics
Junshi Biosciences
Just Biotherapeutics
JW Pharmaceuticals
Kadmon
Kairos Therapeutics
KAKEN PHARMACEUTICAL
Kanwhish Biotechnology
KareBay Biochem
Karolinska University Hospital
Kemp Proteins
KGbio
Kite Pharma
KMD Bioscience
Kodiak Sciences
KYinno
Kymab
Kyoritsuseiyaku
Kyowa Kirin
La Jolla Institute for Immunology
LabGenius
Labtoo
LakePharma
LamKap Bio
LAMPIRE Biological Labs
Lanier Biotherapeutics
Lava Therapeutics
Leadgene Biomedical
Leading Biology
Leads Biolabs
LegoChem Biosciences
Leica Microsystems
LEO Pharma
LG Chem
LifeArc
LifeTein
Ligand Pharmaceuticals
Light Chain Bioscience
Lineage Cell Therapeutics
Lonza
Loxo Oncology
Lunaphore
Lundbeck
Luye Pharma
MAB Discovery
MabGenesis
Mablytics
Mabpharm
MAbSilico
mAbsolve
MabSpace Biosciences
Mabtech
MabVax
Mabworks
MacroGenics
Magenta Therapeutics
Maine Biotechnology Services
Maravai LifeSciences
Masaachusetts General Hospital
Mass Biologics
Maverick Therapeutics
Beijing Mede Taikang Biotechnology
MedAbome
MedGenome
Medicilon
MedImmune
Medix Biochemica
MEDx
MEMO Therapeutics
Memorial Sloan Kettering Cancer Center
Merck
Merus
Mila
MI-mAbs
Mithra Pharmaceuticals
Mitsubishi Tanabe Pharma Corporation
Moderna
ModeX Therapeutics
ModiQuest
Molcure
Molecular Devices
Molecular Templates
MolMed
Mologic
Moradec
MorphoSys
Mount Sinai
MSD
MSM Protein Technologies
Mycenax Biotech
Myrio Therapeutics
Mythic Therapeutics
Nanjing Chia-Tai Tianqing Pharmaceutical Company
Nanocarry Therapeutics
NanoCellect Biomedical
NanoString Technologies
National Cancer Institute
National Research Council of Canada's Human Health Therapeutics Research Centre
National, Heart, Lung, and Blood Institute
NaturalAntibody
Nautilus Systems
NB Health Laboratory
NBE Therapeutics
Nelum
NeoBiotechnologies
NeoClone
Neon Therapeutics
neoX Biotech
Neurimmune
Nexum
Nidus MB Technologies
Nidus BioSciences
Nkarta
Nona BioSciences
Nordic Society of Gynaecological Oncology
Normunity
North Dakota State University
Northway Biotech
NovaRock Biotherapeutics
Novartis
Novo Holdings
Novo Nordisk
Numab Therapeutics
NYU Langone Health
Oak BioSciences
Oblique Therapeutics
Olympic Protein Technologies
OmniAb
OncoC4
OncoOne
OncoResponse
Oncothyreon
Onena Medicines
Ono Pharmaceuticals
Open Monoclonal Technology
Optimeos Life Sciences
OREGA Biotech
OriCell
OriGene Technologies
OriMAbs
Orion
OSE Immunotherapeutics
Ossianix
Oxford Biomedica
OXGENE
Pandion Therapeutics
Panoply Bio
Paragon Therapeutics
Pascal Biosciences
Pediatric Brain Tumor Consortium
Penn Medicine
PerkinElmer
Perseus Proteomics
Pfizer
pH Pharma
Phanes Therapeutics
PharmAbcine
PharmAbs
PharmaEssentia Innovation Research Center
PharmaLegacy
Pharmsynthez
Pierre Fabre
Pinteon Therapeutics
Pioneering Medicines
Pionyr Immunotherapeutics
Potenza Therapeutics
Precision Antibody
Prellis Biologics
ProMab Biotechnologies
Prometheus Authors
Prosci
Protein Alternatives
Proteogenix
ProteoNic
ProtTech
Purdue Pharma
Pure Biologics
PX'Therapeutics
QIMR Berghofer Medical Research Institute
QoolAbs
Quadira Biosciences
Queen's University
Rallybio
Rapid Novor
RayBiotech
RD Biotech
ReCentrics Biotechnology
Regeneron Pharmaceuticals
Resonant Therapeutics
Retrogenix
RevMab Biosciences
Revolve Biotechnologies
Rezolute
Roche
Rockland Immunochemicals
RubrYc Therapeutics
Rx Biosciences
RxBiologics
SAb Biotherapeutics
Saccharo
Salipro Biotech
San Diego Biomedical Research Institute
Sanders Tri-Institutional Therapeutics Discovery Institute
Sanofi
Sanyou Biopharmaceuticals
Sartorius
SBH Sciences
Scandion Oncology
Scotia Biologics
Sea Lane Biotechnologies
Selecxine
Sema4
Sensei Biotherapeutics
Serum Institute of India
Servier
Severance Hospital
Sevion Therapeutics
Shanghai Henlius Biotech
Shanghai KangaBio
Shanghai Pidu Biotechnology
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS
Shire
Sichuan Kelun-Biotech Biopharmaceutical
Siegfried Holding
Simcere
Simon Fraser University
Single Cell Technology
Sino Biological
Sinobioway
Sinopharm
SmartPharm Therapeutics
Sorrento Therapeutics
SOTIO
SouthernBiotech
Specialised Therapeutics
Specifica
Sphere Fluidics
Stanford University
Straterx
Summit Therapeutics
Sunshine Guojian
Surface Oncology
Surrozen
Sutro Biopharma
Suzhou Bright Scistar Biotechnology Company
Syd Labs
Symphogen
Synaffix
Synbio Technologies
Syngene
Synthelis
Tachyon Therapeutics
Takeda
Tanabe Research Laboratories
Tasgen Biotech (Acquried by I-Mab Biopharma)
Tasly Biopharmaceuticals
Taurus Biosciences
TC BioPharm
Technical University of Denmark
Telesis Bio
Telix Pharmaceuticals
Tempus Labs
TeneoBio
TESARO
Tetra Partner Network
Tetragenetics
Teva Pharmaceuticals
TG Therapeutics
The Antibody Company
The Wistar Institute
Theraclone Sciences
Theranyx
ThermoFisher Scientific
Third Venture Biopharma
ThromboGenics
Tizona Therapeutics
Tmunity Therapeutics
Torch Biosciences
TRACON Pharmaceuticals
TRANSCENTA
Transgene
TRIANNI
Tsinghua University
Tubulis
Twist Bioscience
U.S. Naval Medical Research Unit No. 3
UCLA Technology Development Group
Universiti Sains Malaysia
University College London
University of Manchester
University of Oxford
University of Pennsylvania
University of Southampton
University of Surrey
University of Texas MD Anderson Cancer Center
University of Tokyo
University of Zurich
U-Protein (Acquired by ImmunoPrecise Antibodies)
Utrecht University
Vaccinex
ValenzaBio (Acquired by ACELYRIN)
Vall d'Hebron Institute of Oncology
Valneva
VBI Vaccines
VectorB2B
venBio Partners
VERAXA Biotech
Vir Biotechnology
ViralClear Pharmaceuticals
Visterra
Viva Biotech
Voyager Therapeutics
Washington University
Washington University School of Medicine
Westlake Pharmaceuticals Services
Westlake Therapeutics
Wisconsin Alumni Research Foundation
Worg Pharmaceuticals
WuXi AppTec
WuXi Biologics
WuXi STA
Wyss Institute
XBiotech
xCella Biosciences
X-Chem
Xencor
XOMA
Y- Biologics
Yale Cancer Center
Yangyang
YenZym Antibodies
Yinuoke
Ymmunobio
YUMAB
Yurogen Biosystems
Zai Lab
Zebra Biologics
Zhejiang Doer Biologics
Zhejiang Teruisi Biopharmaceuticals
Zoetis
ZoonBio Biotechnology
Zumutor Biologics
Zydus
Zymeworks

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