MediPoint: Total Wrist Reconstruction - APAC Analysis and Market Forecasts
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MediPoint: Total Wrist Reconstruction - APAC Analysis and Market Forecasts
MediPoint: Total Wrist Reconstruction - APAC Analysis and Market Forecasts
Summary
Injuries to any of the bones, ligaments, tendons or nerves in the wrist joint can cause pain. Severe arthritis is the most common condition for patients considering a total wrist replacement surgery. Two major categories of arthritis may affect the wrist joint, namely osteoarthritis and rheumatoid or inflammatory arthritis. Post traumatic arthritis is another reason for the onset of osteoarthritis years later after trauma to the joint. Finally another indication for wrist pain and dysfunction includes carpal tunnel syndrome.
The TWR market in APAC is expected to only have moderate growth, while TWF will be steady. The market is based on and will be driven by the rising prevalence of osteoarthritis and the rising aging population. Countries to watch are India and China, but these markets depend heavily on physician training and the distribution networks and market entry of major players.
Scope
- An overview of arthritis, which includes epidemiology, etiology, symptoms, diagnosis, pathology and treatment guidelines.
- Annualized APAC TWR market revenue and future forecasts from 2009 to 2011, forecast for 7 years to 2018.
- Investigation of current and future market competition for TWR
- Insightful review of the key industry drivers, restraints and challenges as well as predicted impact of key events.
- Competitor assessment including device approval analysis and device sales forecasts.
- Marketed and pipeline product profiles covering efficiency, safety, clinical study details, device approvals, product positioning and device sales forecast.
- Analysis of unmet needs within the market and opportunities for future players.
- Technology trends evaluation to assess strength of pipeline.
- An overview of all devices in development including clinical study details, design and material selection considerations, efficacy reports, and device approval timelines.
- Company profiles including business description, financial overview and SWOT analysis.
- Coverage of key market players.
- Strategic assessment of the TWR device sector through market impact analysis, future market scenario and company analysis.
- Direct quotes from Key Opinion Leaders (KOL) as well as orthopedists
Reasons to buy
- Understand the trends shaping and driving the APAC TWR Market.
- Realize device preferences of physicians who have performed the tests already.
- Access market sizing, forecasts and quantified growth opportunities in the APAC TWR Market through 2018.
- Quantify candidate patient populations to better design product pricing & launch plans.
- Drive revenues, formulate effective sales and marketing strategies and gain in-depth understanding of the competitive landscape.
- Perform benchmarking analysis of growth opportunities against currently marketed products.
- Assess competitiveness of products in market by understanding the strengths and weaknesses of current competition.
- Take a comprehensive look at the market's device pipeline and identify promising, paradigm-shifting products.
- Create an effective counter-strategy to gain a competitive advantage against those currently in the market.
- Organize your sales and marketing efforts by identifying the market categories and segments that present the best opportunities for growth.
- What's the next big thing in APAC TWR market landscape? Identify, understand and capitalize.
Table of Contents
1 Table of Contents 5
1.1 List of Tables 11
1.2 List of Figures 13
2 Introduction 14
2.1 Catalyst 14
3 Disease Overview 15
3.1 Anatomy and Physiology 15
3.2 Pathophysiology 16
3.2.1 Overview 16
3.2.2 Osteoarthritis 16
3.2.3 Rheumatoid Arthritis 17
3.2.4 Carpal Tunnel Syndrome 17
3.2.5 Others 18
3.3 Clinical Presentation 18
3.4 Clinical Outcomes 19
3.4.1 Overview 19
3.4.2 Conservative Therapy 20
3.4.3 Arthroscopic Debridement 20
3.4.4 Proximal Row Carpectomy 20
3.4.5 Total Wrist Fusion 21
3.4.6 Total Wrist Replacement 23
3.4.7 Wrist Fusion Versus Total Wrist Replacement 25
3.5 Epidemiology 27
3.6 Economic Impact 29
3.6.1 Economic Impact of Treating Arthritis 29
3.6.2 Cost Effectiveness of Orthopedic Implants 30
4 Competitive Assessment 31
4.1 Total Wrist Implant 31
4.1.1 Overview of Historical Designs 31
4.1.2 Current Designs 31
4.2 Total Wrist Fusion 44
4.2.1 Overview of Historical Designs 44
4.2.2 Current Designs 44
5 Unmet Needs 53
5.1 Long-Term Clinical Data 53
5.2 Limited Product Offerings 54
5.3 Failure and Revision Rate 55
5.4 Minimal Bone Resection and Other Complications 56
5.5 Lack of Pipeline Products 57
5.6 Need for Better Physician Training 58
6 Pipeline Products 59
6.1 Overview 59
7 Industry Overview 60
7.1 Procedure Volumes 60
7.1.1 Asia-Pacific 61
7.2 Market Access 63
7.2.1 Asia-Pacific 64
7.3 Reimbursement Trends 65
7.3.1 Japan 65
7.3.2 China 66
7.3.3 India 67
7.4 Regulatory Issues/Recalls 67
7.5 Mergers & Acquisitions / Key Partnerships 68
8 Company Profiles 70
8.1 Small Bone Innovation Inc. 70
8.1.1 Overview 70
8.1.2 Portfolio Assessment 70
8.1.3 SWOT Analysis 71
8.2 Depuy Synthes International 71
8.2.1 Overview 71
8.2.2 Portfolio Assessment 72
8.2.3 SWOT Analysis 72
8.3 Integra LifeSciences Inc. 73
8.3.1 Overview 73
8.3.2 Portfolio Assessment 73
8.3.3 SWOT Analysis 74
8.4 Biomet Orthopedics 74
8.4.1 Overview 74
8.4.2 Portfolio Assessment 75
8.4.3 SWOT Analysis 75
8.5 Medartis AG 76
8.5.1 Overview 76
8.5.2 Portfolio Assessment 76
8.5.3 SWOT Analysis 76
8.6 Acumed 77
8.6.1 Overview 77
8.6.2 Portfolio Assessment 77
8.6.3 SWOT Analysis 78
8.7 Tornier N.V. 78
8.7.1 Overview 78
8.7.2 Portfolio Assessment 78
8.7.3 SWOT Analysis 79
8.8 Swemac Orthopaedics AB 80
8.8.1 Overview 80
8.8.2 Portfolio Assessment 80
8.8.3 SWOT Analysis 81
8.9 Zimmer Holdings Inc. 81
8.9.1 Overview 81
8.9.2 Portfolio Assessment 82
8.9.3 SWOT Analysis 82
8.10 Skeletal Dynamics 83
8.10.1 Overview 83
8.10.2 Portfolio Assessment 83
8.10.3 SWOT Analysis 83
9 Market Drivers & Opportunities 84
9.1 Market Drivers 84
9.1.1 Rise in Osteoarthritis 84
9.1.2 Aging 84
9.1.3 Trauma 84
9.1.4 Patient Demand and Awareness 85
9.1.5 Availability of Long-Term Clinical Data 85
9.1.6 Further Technological Advancement 86
9.1.7 Corporate Promotions and Teaching Seminars 87
9.2 Opportunities 87
9.2.1 Expanding Aging and Arthritis Indication 87
9.2.2 Revision Surgery 87
9.2.3 Emerging Markets 88
9.2.4 Capitalizing on Market Fragmentation 88
10 Market Threats & Substitutes 89
10.1 Market Threats 89
10.1.1 Slow Technological Advancement 89
10.1.2 Physician Perception and Learning Curve 89
10.1.3 Complications 90
10.1.4 Cost 90
10.1.5 Lack of Long-Term Studies 91
10.2 Substitutes 91
10.2.1 Therapeutic Options and Fusion 91
11 Country Outlooks & Forecasts 92
11.1 Major Markets Overview 92
11.2 Japan 96
11.2.1 Overview 96
11.2.2 Japan Market Analysis 96
11.3 China 97
11.3.1 Overview 97
11.3.2 China Market Analysis 97
11.4 India 99
11.4.1 Overview 99
11.4.2 India Market Analysis 99
12 Appendix 101
12.1 Abbreviations 101
12.2 Bibliography 102
12.3 Report Methodology 108
12.3.1 Overview 108
12.3.2 Coverage 108
12.3.3 Secondary Research 108
12.3.4 Forecasting Methodology 109
12.3.5 Primary Research – Key Opinion Leader Interviews 110
12.3.6 Primary Research – Physician Survey 110
12.3.7 Expert Panel Validation 110
12.4 Physicians and Specialists Included in this Study 111
12.4.1 Dr. Philippe Bellemère 111
12.4.2 Dr. Vikas Gupta, MBBS, MS 111
12.4.3 William H. Seitz, Jr., MD 111
12.4.4 Robert M. Szabo, MD, MPH 111
12.4.5 David Warwick, MD, BM, DIMC, FRCS (Orth) 111
12.5 About the Authors 112
12.5.1 Analysts 112
12.5.2 Global Head of Healthcare 113
12.6 About MediPoint 113
12.7 About GlobalData 113
12.8 Contact Us 114
12.9 Disclaimer 114
List of Tables
Table 1: Clinical Symptoms and Descriptions 18
Table 2: Advantages and Disadvantages of Wrist Fusion and Total Wrist Replacement 26
Table 3: Direct and Indirect Costs of Arthritis 29
Table 4: Universal 2 Total Wrist Implant System (Integra LifeSciences Inc.) 33
Table 5: SWOT Universal 2 Total Wrist Implant System 34
Table 6: ReMotion Total Wrist (Small Bone Innovations, Inc.) 35
Table 7: SWOT ReMotion Total Wrist 35
Table 8: Maestro Total Wrist System (Biomet Orthopedics) 37
Table 9: SWOT Maestro Total Wrist System 37
Table 10: Tornier Resurfacing Capitate Pyrocarbon Implant 39
Table 11: SWOT:Tornier Resurfacing Capitate Pyrocarbon Wrist Implant 39
Table 12: Motec Wrist Joint Prosthesis (Swemac Orthopaedics AB) 41
Table 13: SWOT Motec Wrist Joint Prosthesis 42
Table 14: MWP III Total Wrist Prosthesis (Zimmer Inc.) 43
Table 15: SWOT MWP III Total Wrist Prosthesis 43
Table 16: LCP Wrist Fusion Set (DePuy Synthes, Johnson & Johnson Co.) 46
Table 17: SWOT LCP Wrist Fusion Set 46
Table 18: Integra Total Wrist Fusion System (Integra LifeSciences Inc.) 48
Table 19: SWOT Integra Total Wrist Fusion System 48
Table 20: Arthrodesis System 2.0/2.3, 2.5 APTUS Wrist (Medartis AG) 50
Table 21: SWOT Arthrodesis System 2.0/2.3, 2.5 APTUS Wrist 50
Table 22: Arthrodesis System 2.0/2.3, 2.5 APTUS Wrist (Medartis AG) 52
Table 23: SWOT Implate Wrist Arthrodesis Nail 52
Table 24: Complications and Risks for TWR and TWF 56
Table 25: Product Components and Costs 63
Table 26: Company Profile – Small Bone Innovation Inc. 70
Table 27: SWOT Analysis – Small Bone Innovations Inc. 71
Table 28: Company Profile – Depuy Synthes International 72
Table 29: SWOT Analysis – Depuy Synthes International 72
Table 30: Company Profile – Integra LifeSciences Inc. 73
Table 31: SWOT Analysis – Integra LifeSciences Inc. 74
Table 32: Company Profile – Biomet Orthopedics 75
Table 33: SWOT Analysis – Biomet Orthopedics 75
Table 34: Company Profile – Medartis AG 76
Table 35: SWOT Analysis – Medartis AG 76
Table 36: Company Profile – Acumed LLC 77
Table 37: SWOT Analysis – Acumed LLC 78
Table 38: Company Profile – Tornier N.V. 79
Table 39: SWOT Analysis – Tornier N.V. 79
Table 40: Company Profile – Swemac Orthopaedics AB 80
Table 41: SWOT Analysis – Swemac Orthopaedics AB 81
Table 42: Company Profile – Zimmer Holdings Inc. 82
Table 43: SWOT Analysis – Zimmer Holdings, Inc. 82
Table 44: Company Profile – Skeletal Dynamics LLC 83
Table 45: SWOT Analysis – Skeletal Dynamics LLC 83
Table 46: APAC Sales ($m) Forecast for TWF and TWR, 2009–2018 92
Table 47: Japan Sales ($m) Forecast for TWF and TWR, 2009–2018 96
Table 48: China Sales ($m) Forecast for TWF and TWR, 2009–2018 97
Table 49: India Sales ($m) Forecast for TWF and TWR, 2009–2018 100
List of Figures
Figure 1: Anatomy of the Wrist 15
Figure 2: Treatment Paradigm for Wrist Arthritis 19
Figure 3: Wrist Arthrodesis with a Fusion Plate 22
Figure 4: Total Wrist Arthroplasty 24
Figure 5: Population with Wrist Arthritis in Major Markets, 2009–2018 27
Figure 6: Disease Segments of Wrist Arthritis 28
Figure 7: Universal 2 Total Wrist Implant System (Integra LifeSciences Inc.) 32
Figure 8: ReMotion Total Wrist (Small Bone Innovations, Inc.) 34
Figure 9: Maestro Total Wrist System (Biomet Orthopedics) 36
Figure 10: Tornier Resurfacing Capitate Pyrocarbon Implant 38
Figure 11: Motec Wrist Joint Prosthesis (Swemac Orthopaedics AB) 41
Figure 12: MWP III Total Wrist Prosthesis (Zimmer Inc.) 42
Figure 13: LCP Wrist Fusion Set (DePuy Synthes, Johnson & Johnson Co.) 45
Figure 14: Integra Total Wrist Fusion System (Integra LifeSciences Inc.) 47
Figure 15: Arthrodesis System 2.0/2.3, 2.5 APTUS Wrist (Medartis AG) 49
Figure 16: Implate Wrist Arthrodesis Nail (Skeletal Dynamics LLC) 51
Figure 17: Importance of Safety of Arthrodesis and Arthroplasty Implants 57
Figure 18: Asia-Pacific Arthrodesis and Arthroplasty Procedure Volumes (2009–2018) 62
Figure 19: APAC Sales ($m) Forecast for TWR and TWF, 2009–2018 93
Figure 20: TWR Revenue by APAC Market, 2009 and 2018 94
Figure 21: TWF Revenue by APAC Market, 2009 and 2018 95
Figure 22: Japan TWR and TWF Market, 2009–2018 96
Figure 23: China TWR and TWF Market, 2009–2018 98
Figure 24: India TWR and TWF Market, 2009–2018 100
Companies Mentioned
Small Bone Innovation Inc.
Depuy Synthes International
Integra LifeSciences Inc.
Biomet Orthopedics
Medartis AG
Acumed
Tornier N.V.
Swemac Orthopaedics AB
Zimmer Holdings Inc.
Skeletal Dynamics
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Orthopedic Industry: MediPoint: Total Wrist Reconstruction - APAC Analysis and Market Forecasts
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