Leading Generic Drug Makers Unite to Pledge Capacity for Developing and Delivering Affordable COVID-19 Interventions as Pandemic Intensifies
18 companies join the effort by Medicines Patent Pool to accelerate global access to effective COVID-19 treatments via a pool for voluntary product licences
GENEVA, Nov. 12, 2020 /PRNewswire/ -- With COVID-19 infections surging worldwide, a united group of 18 companies representing a large portion of the world's generic pharmaceutical manufacturers pledged to work together to accelerate access to hundreds of millions of doses of new interventions for low- and middle-income countries via the non-profit Medicines Patent Pool (MPP).
"This unprecedented cooperation from companies that are typically competitors represents a breakthrough in our efforts to level the playing field for access to drugs that will be crucial to controlling and defeating this pandemic," said Charles Gore, Executive Director of MPP. "These are companies with an excellent track record of working with originators to ensure generic versions of their innovations meet high standards for quality—while answering the need for more affordable, accessible therapies."
Gore noted that collectively the 18 companies joining the pledge have the capacity to deliver substantial amounts of conventional drugs, technically known as "small molecules" in industry parlance, and an increasing ability to produce more molecules known as biologics. Biologics include monoclonal antibodies targeting COVID-19 that have shown promise as potential ways to either treat or prevent infections—but cost and manufacturing capacity pose substantial barriers to deploying them globally.
Gore said he hopes the pledge by such a respected group of generic industry players to produce large volumes of high-quality COVID-19 treatments will encourage firms now developing either new or re-purposed therapies to negotiate agreements allowing rapid access to those in need. This can be either through licensing of their intellectual property, or where licences are not needed, facilitating ways to scale up manufacturing capacity to meet the high demands.
"We welcome this pioneering collaboration and encourage others to join. Making sure there is enough supply capacity of potential game-changing treatments for COVID-19 is critical to ensure equitable access in low- and middle-income countries. Using the proven MPP model to ensure access to effective and affordable health solutions not only makes sense in this COVID-19 emergency but is the right thing to do," said Dr Philippe Duneton, Executive Director of Unitaid.
The companies joining the effort are connected by their past work with MPP, an organisation created in 2010 by the global health initiative Unitaid to negotiate patent licence agreements with pharmaceutical companies that are placed in a pool to make them more easily accessible for generic manufacturers. Thus far, agreements negotiated by MPP with companies such as ViiV Healthcare, Bristol Myers Squibb and AbbVie have allowed generic producers to provide over 15 billion doses of HIV and hepatitis C medicines to low- and middle-income countries. Despite the logistical challenges of the pandemic, in the first six months of 2020 alone, MPP's licensees have delivered three billion doses.
Combining the capacity of generic firms with patent agreements negotiated by MPP is increasingly viewed as an important addition to efforts to ensure COVID-19 interventions are available outside of the world's wealthiest countries. For example, the European Union has called for "maximizing accessibility" to the fruits of COVID-19 R&D via initiatives that include "the pooling of technology to any UN-endorsed patent pool, such as the Medicines Patent Pool." The G20 joint Finance and Health Ministers' statement in September, also cited voluntary licensing of intellectual property as one of the key tools in the COVID-19 response.
Several signatories have stepped forward to underscore the importance of the pledge, their quotes can be found here: read all.
Full list of first signees of the open pledge:
- Adcock Ingram
- Arene
- Aurobindo
- Beximco
- Celltrion
- Desano
- Emcure
- Hetero
- Langhua Pharma
- Laurus Labs
- Lupin
- Macleods
- Mangalam
- Micro Labs
- Natco
- Strides Shasun
- Sun Pharma
- Zydus Cadila
About the Medicines Patent Pool
The Medicines Patent Pool (MPP) is a United Nations-backed public health organisation working to increase access to, and facilitate the development of, life-saving medicines for low- and middle-income countries.
Through its innovative business model, MPP partners with civil society, governments, international organisations, industry, patient groups and other stakeholders, to prioritise and license needed medicines and pool intellectual property to encourage generic manufacture and the development of new formulations.
To date, MPP has signed agreements with ten patent holders for thirteen HIV antiretrovirals, one HIV technology platform, three hepatitis C direct-acting antivirals and a tuberculosis treatment. MPP was founded by Unitaid, which continues to be MPP's main funder. MPP's work on access to essential medicines is also funded by the Swiss Agency for Development and Cooperation (SDC).
https://medicinespatentpool.org
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SOURCE Medicines Patent Pool
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https://medicinespatentpool.org
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