Le Bonheur Children's Hospital Successfully Creates Airway and Voice Box for Child
World's first recorded case of a successful total voice box reconstruction in a child
MEMPHIS, Tenn., Aug. 6, 2019 /PRNewswire/ -- Le Bonheur Children's Hospital reconstructed an airway and voice box in the world's first successful surgery of its kind for 2-year-old Cooper Kilburn from Adamsville, Tenn.
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A team of pediatric experts, led by Le Bonheur Children's Hospital and The University of Tennessee Health Science Center Otolaryngologist Jerome Thompson, M.D. used a rib graft to create a voice box and establish a viable airway for Cooper.
When his mother Brooke was 16 weeks pregnant with Cooper, she was in a car wreck that prompted her to visit the obstetrician for an ultrasound to make sure all was well with her baby. "The doctor saw something wrong but didn't know what it was," said Brooke. The ultrasound revealed that fluid was building in Cooper's chest because of a rare condition – total laryngeal agenesis due to congenital high airway obstruction syndrome (CHAOS).
Cooper had no airway, no larynx and therefore no voice or way to breathe outside the womb. Their doctor referred Brooke and Brad Kilburn to Le Bonheur Children's and Dr. Thompson in hopes of saving Cooper's life.
Laryngeal agenesis occurs when larynx development is halted during pregnancy. The reasons for this condition are unknown.
- Larynx development begins in the fourth week of fetal growth. The windpipe starts as a solid tube and hollows out from the top and bottom to create an airway.
- About 50 documented cases of total laryngeal agenesis exist throughout history.
- Most babies do not survive to term due to lack of diagnosis.
- Diagnosis depends on the discovery of indirect problems – like Cooper's fluid-filled lungs. A lack of airway is rarely identified in fetal screenings.
- Survival depends on immediate diagnosis in utero and a rapid tracheostomy at birth to provide an airway.
Le Bonheur Children's Fetal Center, along with Dr. Thompson and his team, put together a plan for Cooper to survive the difficult delivery. As planned, Cooper was delivered next door to Le Bonheur at Regional One Health. During delivery, Dr. Thompson performed an ex utero intrapartum treatment (EXIT) procedure, a partial caesarean section that allowed Cooper to continue to receive oxygen via his mother's placenta. While Brooke was recovering, he was transported to Le Bonheur's Neonatal Intensive Care Unit (NICU) so he could continue treatment.
Cooper stayed in Le Bonheur's NICU for 324 days and had beaten the odds for survival. Once home, he still depended on help to breathe 24 hours a day. Any health issue threatened his young life.
Two years and eight surgeries later, the Kilburn family was back at Le Bonheur. Cooper had developed well and continued to follow developmental milestones, despite never being able to make a sound. According to Dr. Thompson, "our goal was to create an anatomical airway, get him off the trach and, possibly, give him a voice."
There have been only a handful of attempts to create an anatomical airway from scratch and all have been unsuccessful.
The team at Le Bonheur included pediatric experts from ENT, neonatology, pulmonology, pediatric surgery and critical care. "We planned for this surgery from day one of Cooper's life," said Thompson. "Everyone from the nurses to surgery technicians to the neonatal team rose to the challenge and worked together for this surgery to be a success."
The four-hour surgery was conducted in tandem with pediatric surgeon Ying Weatherall, M.D. and Thompson. Weatherall removed two of Cooper's ribs to use to construct his new voice box.
After navigating through complicated throat anatomy, Thompson and fellow otolaryngologist Jennifer McLevy, M.D. began to create the new voice box. Thomspon used the ribs to create the walls of a voice box.
The Kilburn family and Le Bonheur experts had to wait six weeks to determine if the surgery successfully created an airway for Cooper.
According to Dr. Thompson our goal was to create an anatomical airway, give him an alternative airway and hopefully an opportunity to find his voice
To learn more about Cooper's journey, visit www.lebonheur.org/promise.
About Le Bonheur Children's Hospital
Le Bonheur Children's Hospital in Memphis, Tenn., treats children each year through community programs, regional clinics and a 255 bed state-of-the-art hospital. Le Bonheur serves as a primary teaching affiliate for the University Tennessee Health Science Center and trains more than 350 pediatricians and specialists each year. Nationally recognized, Le Bonheur is ranked by U.S. News & World Report as a Best Children's Hospital.
For more information, please call (901) 287-6030 or visit lebonheur.org. Connect with us at facebook.com/lebonheurchildrens, twitter.com/lebonheurchild or on Instagram at lebonheurchildrens.
CONTACT:
David Henson
(423) 304-9400
[email protected]
SOURCE Le Bonheur Children's Hospital
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