Global Matrigel Market Soars with a CAGR of 11.5% | Insights on Phenol Red and Phenol Red-Free Applications - Valuates Reports

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Jan 23, 2025, 10:20 ET

BANGALORE, India, Jan. 23, 2025 /PRNewswire/ -- Matrigel Market is Segmented by Type (Contains Phenol Red, Phenol Red Free), by Application (Biotechnology and Pharmaceutical Companies, Research and Academic Institutes).

The Global Matrigel Market is projected to grow from USD 85 Million in 2024 to USD 163.3 Million by 2030, at a Compound Annual Growth Rate (CAGR) of 11.5% during the forecast period.

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Major Factors Driving the Growth of Matrigel Market:

The Matrigel market is experiencing robust growth, driven by its critical role in advanced research and development across biotechnology, pharmaceutical, and academic sectors. Matrigel's ability to mimic the extracellular matrix makes it indispensable for 3D cell culture, cancer modeling, and stem cell research.

The market benefits from collaborations between research organizations and private companies, accelerating innovations in personalized medicine and biotherapeutics. As the demand for precision and predictive preclinical models grows, Matrigel continues to expand its applications in regenerative medicine, oncology, and drug discovery.

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TRENDS INFLUENCING THE GROWTH OF THE MATRIGEL MARKET:

The inclusion of phenol red in Matrigel formulations has significantly contributed to the growth of the Matrigel market by enhancing its utility in cell culture applications. Phenol red acts as a pH indicator, providing researchers with a visual cue of the culture medium's pH levels, ensuring an optimal environment for cell growth and differentiation.

This feature is particularly valuable in regenerative medicine, stem cell research, and drug discovery, where consistent results are critical. Additionally, phenol red-containing Matrigel is widely used in 3D cell culture systems for studying cancer, organoids, and tissue engineering due to its ability to mimic in vivo environments effectively. The demand for reliable and reproducible research tools in biotechnology and pharmaceutical industries has further boosted the adoption of phenol red-enhanced Matrigel.

The increasing demand for phenol red-free Matrigel is a significant growth driver in the Matrigel market, particularly in applications requiring minimal interference with cellular signaling pathways. Phenol red-free formulations are preferred in sensitive experiments, including hormone research, stem cell differentiation, and cancer studies, where the presence of phenol red may alter experimental outcomes. This type of Matrigel ensures accurate and reproducible results, making it an essential tool for precision research. The rising adoption of phenol red-free Matrigel in pharmaceutical and biotechnology sectors reflects the growing emphasis on high-quality, interference-free reagents for drug discovery and therapeutic development. Additionally, its widespread use in in vitro fertilization (IVF) procedures highlights its importance in clinical and diagnostic applications.

Matrigel provides an extracellular matrix (ECM)-like environment that supports cell attachment, proliferation, and differentiation, making it indispensable for drug discovery, toxicology studies, and tissue engineering. Pharmaceutical companies utilize Matrigel to evaluate drug efficacy and safety in 3D cell culture systems, enabling more accurate predictions of in vivo responses. In the biotechnology sector, Matrigel is widely used for stem cell research, organoid development, and cancer modeling, driving innovations in regenerative medicine and oncology. The increasing focus on personalized medicine and biotherapeutics has further heightened the demand for high-quality Matrigel formulations. Collaborations between research organizations and industry players, along with rising investments in life sciences, continue to expand the applications of Matrigel, contributing significantly to market growth.

The growing adoption of 3D cell culture models is a key factor driving the Matrigel market. Unlike traditional 2D cultures, 3D systems mimic the in vivo cellular environment, offering more accurate and physiologically relevant results. Matrigel, with its ECM-like composition, provides an ideal scaffold for 3D cultures, enabling the study of complex cellular behaviors such as migration, invasion, and differentiation.

This capability has made Matrigel indispensable for cancer research, drug discovery, and tissue engineering. Additionally, regulatory agencies emphasize the need for more predictive preclinical models, further fueling the demand for 3D culture systems. Pharmaceutical and biotechnology companies are increasingly incorporating Matrigel into their workflows to improve the success rate of drug development pipelines.

Stem cell research represents a significant growth area for the Matrigel market. Matrigel provides a supportive microenvironment for the proliferation and differentiation of stem cells, making it essential for regenerative medicine and therapeutic applications. Researchers use Matrigel to culture pluripotent and mesenchymal stem cells, ensuring their stability and functionality for downstream applications. Its role in organoid development has further expanded its utility in studying organ-specific diseases and developing personalized treatment options.

Additionally, the ability of Matrigel to support 3D stem cell cultures has enhanced its importance in tissue engineering and cellular therapy research. As global research into stem cell-based therapies intensifies, the demand for reliable and high-quality Matrigel formulations continues to grow, contributing significantly to market expansion.

The expanding scope of cancer research has significantly boosted the demand for Matrigel, particularly in studying tumor biology and developing anti-cancer therapies. Matrigel provides an ECM-like environment that supports the growth of tumor spheroids and organoids, enabling researchers to model the tumor microenvironment in vitro. This capability is critical for understanding tumor progression, metastasis, and resistance mechanisms, driving the development of targeted therapies. Pharmaceutical companies use Matrigel-based models to evaluate the efficacy of novel cancer drugs, reducing the reliance on animal studies and improving translational outcomes. Additionally, Matrigel is widely used in invasion and migration assays to study the behavior of cancer cells under different conditions. The increasing prevalence of cancer worldwide and the push for personalized oncology solutions continue to drive investments in cancer research. Consequently, the role of Matrigel in advancing cancer studies remains integral to its market growth.

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MATRIGEL MARKET SHARE

The Matrigel market exhibits strong growth across regions, with North America leading due to its advanced research infrastructure, significant investments in biotechnology, and a strong pharmaceutical sector. US & Canada is the largest market, with a share of about 38%, which is driven by extensive funding for cancer and stem cell research.

In terms of application, Biotechnology and Pharmaceutical Companies has a share about 73 percent.

In terms of product type, Contains Phenol Red is the largest segment, occupied for a share of about 68%.

Global key players of Matrigel include Corning and Thermo Fisher Scientific, etc. The top two players hold a share over 73%.

Key Companies:

Corning Inc
Yeasen Biotechnology
Solarbio Science & Technology
R&D Systems
MEGAROBO
ACROBiosystems
Beyotime
Live Biotechnology
Mogengel Biotechnology
Thermo Fisher Scientific

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