The increasing demand for cancer monoclonal antibodies is mainly driven by the rising incidence of cancer, the growing prevalence of risk factors like smoking, radiation exposure, unhealthy lifestyles, and other contributing factors. Additionally, the surge in research and development activities by market players is expected to further fuel this demand throughout the forecast period from 2024 to 2030.
LAS VEGAS, Sept. 2, 2024 /PRNewswire/ -- DelveInsight's Cancer Monoclonal Antibodies Market Insights report provides the current and forecast market analysis, individual leading cancer monoclonal antibodies companies' market shares, challenges, cancer monoclonal antibodies market drivers, barriers, trends, and key market cancer monoclonal antibodies companies in the market.
Key Takeaways from the Cancer Monoclonal Antibodies Market Report
- As per DelveInsight estimates, North America is anticipated to dominate the global cancer monoclonal antibodies market during the forecast period.
- In the application segment of the cancer monoclonal antibodies market, the breast cancer category had a significant revenue share in the cancer monoclonal antibodies market in 2023.
- Notable cancer monoclonal antibodies companies such as GSK plc, F. Hoffmann-La Roche Ltd., Merck & Co., Inc., Novartis AG, Johnson and Johnson Services Inc., Spectrum Pharmaceuticals Inc., Eurofins Scientific, Genmab AS, Bristol Myers Squibb Company, Elli Lilly and Company, Amgen, Inc., AbbVie Inc., AstraZeneca Plc., CStone Pharmaceuticals, HiFiBiO Therapeutics, and several others, are currently operating in the cancer monoclonal antibodies market.
- In April 2024, CE approved the VENTANA® HER2 (4B5) Rabbit Monoclonal Primary Antibody RxDx* to identify metastatic breast cancer patients with low HER2 expression for whom ENHERTU® (trastuzumab deruxtecan) may be considered as a targeted treatment.
- In December 2023, CStone Pharmaceuticals announced that the National Medical Products Administration (NMPA) of China approved the supplemental biologics license application (sBLA) for sugemalimab (Cejemly®) in combination with fluorouracil and platinum-based chemotherapy as first-line treatment of unresectable locally advanced, recurrent, or metastatic esophageal squamous cell carcinoma (ESCC). Sugemalimab became the world's first anti-PD-L1 monoclonal antibody approved for the first-line ESCC indication.
To read more about the latest highlights related to the cancer monoclonal antibodies market, get a snapshot of the key highlights entailed in the Global Cancer Monoclonal Antibodies Market Report
Cancer Monoclonal Antibodies Overview
Monoclonal antibodies (mAbs) have revolutionized cancer treatment by offering highly targeted therapies that specifically attack cancer cells while sparing healthy tissue. These antibodies are laboratory-made molecules designed to bind to specific antigens on the surface of cancer cells. By recognizing these unique markers, monoclonal antibodies can interfere with the growth and spread of cancer in several ways. For example, they can block signals that stimulate cancer cell proliferation, mark cancer cells for destruction by the immune system, or deliver toxic substances directly to the cancer cells. This specificity reduces the side effects typically associated with conventional chemotherapy and radiation, making mAbs an essential component of modern oncology.
There are several types of monoclonal antibodies used in cancer treatment, including naked mAbs, which work by themselves, and conjugated mAbs, which are linked to drugs or radioactive particles. Some well-known examples include Rituximab, used in the treatment of certain types of lymphoma, and Trastuzumab, which targets HER2-positive breast cancer. These therapies have shown significant success in improving survival rates and quality of life for many patients. However, challenges remain, such as the development of resistance by cancer cells and the high cost of production. Ongoing research aims to overcome these hurdles by developing more effective and affordable mAbs, as well as combining them with other treatments to enhance their efficacy.
Cancer Monoclonal Antibodies Market Insights
North America held the largest share of the cancer monoclonal antibodies market in 2023, driven by several factors. The region's leading position is attributed to the rising incidence of cancers, greater exposure to carcinogens such as smoking, radiation, and viruses, and recent regulatory approvals that favor the growth of the cancer monoclonal antibodies market in North America.
Furthermore, the increasing number of regulatory approvals for these antibodies is expected to further stimulate market growth. For instance, in October 2022, the FDA approved the combination of durvalumab (IMFINZI), a human monoclonal antibody, with the experimental drug tremelimumab for treating unresectable hepatocellular carcinoma.
The large patient population in North America is likely to drive demand for cancer monoclonal antibodies, leading to market expansion in the coming years. Therefore, the combined influence of these factors is expected to contribute significantly to the growth of the cancer monoclonal antibodies Market in North America from 2024 to 2030.
To know more about why North America is leading the market growth in the cancer monoclonal antibodies market, get a snapshot of the Cancer Monoclonal Antibodies Market Outlook
Cancer Monoclonal Antibodies Market Dynamics
The global market for cancer monoclonal antibodies has experienced significant growth over the past decade, driven by the increasing incidence of cancer, advancements in biotechnology, and the rising demand for targeted therapies. Monoclonal antibodies, which are designed to specifically target cancer cells while sparing healthy tissue, have become a cornerstone in the treatment of various cancers. Their specificity and reduced side effects compared to traditional chemotherapy have made them an attractive option for both patients and healthcare providers.
One of the key dynamics shaping the cancer monoclonal antibodies market is the ongoing innovation in antibody engineering. Techniques such as antibody-drug conjugates, bispecific antibodies, and immune checkpoint inhibitors have expanded the therapeutic potential of mAbs, leading to the development of more effective and versatile cancer treatments. These innovations have not only enhanced the efficacy of existing therapies but have also opened up new avenues for addressing previously untreatable or resistant forms of cancer.
The competitive landscape of the market is also influenced by the expiration of patents on several blockbuster mAbs, paving the way for biosimilars to enter the market. Biosimilars, which are essentially generic versions of biologic drugs, offer similar efficacy at a lower cost, making cancer treatment more accessible. However, the introduction of biosimilars has also intensified competition among pharmaceutical companies, driving the need for continuous innovation and the development of next-generation therapies to maintain market share.
Regulatory and reimbursement challenges also play a crucial role in the market dynamics. The stringent regulatory requirements for the approval of mAbs, coupled with the high costs associated with their development and manufacturing, can pose barriers to market entry. Additionally, securing favorable reimbursement from healthcare systems is critical for the widespread adoption of these therapies. As healthcare budgets become increasingly strained, especially in the wake of the COVID-19 pandemic, the cost-effectiveness of mAbs will likely be a focal point in discussions between pharmaceutical companies, regulators, and payers.
In conclusion, the cancer monoclonal antibodies market is poised for continued growth, driven by technological advancements, the entry of biosimilars, and the rising demand for personalized cancer therapies. However, the market will need to navigate challenges related to regulation, competition, and cost-effectiveness to sustain its momentum. As research and development in the field of immuno-oncology continue to advance, the landscape of cancer treatment is likely to evolve, offering new hope for patients and further solidifying the role of monoclonal antibodies in cancer care.
Get a sneak peek at the cancer monoclonal antibodies market dynamics @ Cancer Monoclonal Antibodies Market Dynamics Analysis
Report Metrics |
Details |
Coverage |
Global |
Study Period |
2021–2030 |
Cancer Monoclonal Antibodies Market CAGR |
~10% |
Cancer Monoclonal Antibodies Market Size by 2030 |
~USD 157 Billion |
Key Cancer Monoclonal Antibodies Companies |
GSK plc, F. Hoffmann-La Roche Ltd., Merck & Co., Inc., Novartis AG, Johnson and Johnson Services Inc., Spectrum Pharmaceuticals Inc., Eurofins Scientific, Genmab AS, Bristol Myers Squibb Company, Elli Lilly and Company, Amgen, Inc., AbbVie Inc., AstraZeneca Plc., CStone Pharmaceuticals, HiFiBiO Therapeutics, among others |
Cancer Monoclonal Antibodies Market Assessment
- Cancer Monoclonal Antibodies Market Segmentation
- Cancer Monoclonal Antibodies Market Segmentation By Type: Humanized Antibodies, Chimeric Antibodies, Murine Antibodies
- Cancer Monoclonal Antibodies Market Segmentation By Application: Blood Cancer, Breast Cancer, Liver Cancer, Colorectal Cancer, and Others
- Cancer Monoclonal Antibodies Market Segmentation By End Users: Hospitals, Research Institutions & Laboratories, and Others
- Cancer Monoclonal Antibodies Market Segmentation By Geography: North America, Europe, Asia-Pacific, and Rest of World
- Porter's Five Forces Analysis, Product Profiles, Case Studies, KOL's Views, Analyst's View
Which MedTech key players in the cancer monoclonal antibodies market are set to emerge as the trendsetter explore @ Cancer Monoclonal Antibodies Companies
Table of Contents
1 |
Cancer Monoclonal Antibodies Market Report Introduction |
2 |
Cancer Monoclonal Antibodies Market Executive Summary |
3 |
Competitive Landscape |
4 |
Regulatory Analysis |
5 |
Cancer Monoclonal Antibodies Market Key Factors Analysis |
6 |
Cancer Monoclonal Antibodies Market Porter's Five Forces Analysis |
7 |
Cancer Monoclonal Antibodies Market Layout |
8 |
Cancer Monoclonal Antibodies Market Company and Product Profiles |
9 |
KOL Views |
10 |
Project Approach |
11 |
About DelveInsight |
12 |
Disclaimer & Contact Us |
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SOURCE DelveInsight Business Research, LLP
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