Exploring RNAi Drug Delivery Innovations in the Global Market 2023-2028 - Unveiling Orphan Drug Opportunities and Novel Nanoparticle Delivery Breakthroughs

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Aug 24, 2023, 14:00 ET

DUBLIN, Aug. 24, 2023 /PRNewswire/ -- The "RNAi Drug Delivery: Technologies and Global Markets" report has been added to ResearchAndMarkets.com's offering.

The global RNAi drug delivery market is projected to reach a value of $2.7 billion by 2028 from $1.08 billion in 2023, growing at a CAGR of 20.5%

This comprehensive research report ventures into the intricate categorization of the nucleic acid drugs market, meticulously dissecting it by type and delving into major product segments, conjugated and encapsulated.

In recent years, the landscape of nucleic acid drugs has undergone a remarkable transformation, ushering in a new era of therapeutic possibilities. A closer examination reveals the intricate web of non-viral vectors employed for encapsulation, ranging from polymers and lipids to other intriguing entities like inorganic materials and hybrid systems.

This captivating market analysis doesn't stop there; it further fragments the terrain based on molecule types, delivery modes, and therapeutic areas. With a discerning eye, the report segregates applications into therapeutic and research-based domains, shedding light on the multifaceted realm these drugs inhabit.

The groundwork for nucleic acid drugs may have been laid over the course of history, but recent breakthroughs have propelled them into the forefront of medical innovation. Among the catalysts, two pivotal forces stand out: the triumphant advent of COVID-19 vaccines, founded upon mRNA and lipid-based delivery, and the escalating endorsement of nucleic acid drugs, ready to confront erstwhile "undruggable" and rare diseases.

The last five years saw approval of siRNA-based drugs. These comprise a different class of nucleic acid drugs that cannot be delivered naked in the human body. Hence there is a need for these molecules to be attached to a delivery agent. The market for nucleic acid drugs is expanding, so a growing demand for the drug delivery agents is also increasing. Drug delivery has been a restricting point in the application of nucleic acid drugs. There is therefore constant research and development regarding the drug delivery systems of nucleic acid drugs.

The major driver of the market includes the increasing investment in the nucleic acid drug segment. The nucleic acid companies have been attracting investments from various sources, such as venture capitalists and seed investments. Even big pharmaceutical companies are keeping a close watch on new companies for mergers and acquisitions.

The drugs currently available on the market are targeted toward rare diseases, and such drugs are allocated orphan drug status. They enjoy many benefits such as faster approval and even tax benefits, which are major drivers for the market. The opportunity to target undruggable diseases is also huge and will spur the market forward.

The major restraint affecting market growth is the addition of other technologies, such as CSPIR. The regulations are also not globally uniform, and they vary drastically for nucleic acid drugs. Another major restraint is the high prices of such drugs, which limit their access. The awareness level for such diseases is also low, which negatively impacts the market.

Report Includes

An up-to-date overview and industry analysis of the global markets for RNA interference (RNAi) drug delivery technologies
Analyses of the global market trends, with historic market revenue (sales figures) from 2020 to 2022, estimates for 2023, and projections of compound annual growth rates (CAGRs) through 2028
Estimation of the actual market size and revenue forecast for the RNAi drug delivery technologies market, and corresponding market share analysis based on type of RNAi, therapeutic area, and region
Discussion of major growth drivers, industry-specific challenges, regulatory aspects, and technology advancement that will shape the market for RNAi drug delivery technologies as a basis for projecting demand in the next few years (2023-2028)
Review of key patent grants and patent applications on RNAi drug delivery markets, and emerging technologies and new developments within the marketplace
Latest information on the mergers and acquisition deals, partnerships, agreements, collaborations, and other strategic alliances within the marketplace
Insight into the recent industry structure, competitive aspects of each product segments, increasing investment on R&D activities, market growth strategies, and company revenue share analysis
A look at commercial opportunities in the RNAi research tools and reagents, recent progress and future opportunities for RNAi therapeutics in various disease classifications, clinical trial applications, and potential markets for future developments
Identification of the major stakeholders and analysis of the competitive landscape based on recent developments, segmental revenues, and operational integration
Descriptive company profiles of the leading global players of the industry, including Alnylam Pharmaceuticals, Benitec Biopharma, Ionis Phamaceutical, Novo Nordisk and Sirnaomics Inc.

Company Profiles

Alnylam Pharmaceuticals Inc.
Arcturus Therapeutics Inc.
Arbutus Biopharma Corp.
Arrowhead Pharmaceuticals Inc.
Benitec Biopharma
Cellecta Inc.
Eleven Therapeutics
Genevant Sciences Corp.
Ionis Pharmaceuticals Inc.
Mirimus, Inc.
Novo Nordisk
Nanode Therapeutics Inc.
Olix Pharmaceuticals
Phio Pharmaceuticals Corp.
Silence Therapeutics plc
Sirnaomics Inc.
Somagenics, Inc.

Key Topics Covered:

Chapter 1 Introduction

Study Goals and Objectives
Reasons for Doing the Study
Scope of Report
What's New in this Update?
Research Methodology
Geographic Breakdown

Chapter 2 Summary and Highlights

Market Outlook

Chapter 3 Market Overview

Introduction
History of Nucleic Acid Drugs
Antisense Oligonucleotides
Rna
Drug Delivery System
Nucleic Acid Drugs
Inhibition Type
Antisense Oligonucleotide
Regulations
Pre-Clinical IND
Covid-19 Impact Analysis on the Rnai Drug Delivery Markets
Positive Impact of Covid-19
Negative Effect of Covid-19

Chapter 4 Market Dynamics

Market Drivers
Approved Rnai Drugs
Venture Funding Increased in Rnai Drugs
Rnai Drugs Designated as Orphan Drugs
New Nanoparticle Technologies for Drug Delivery Systems
Market Restraints
High Drug Costs
Lack of Awareness Regarding Rare Diseases
Clustered Regularly Interspaced Short Palindromic Repeats Technology Application Growing
Market Opportunities
Application in Cancer Treatment
Infectious Disease and Rnai Drugs

Chapter 5 Nucleic Acid Drug Delivery Technology Market by Type

Encapsulation
Viral Vector-Based
Non-Viral Vector-Based Delivery System
Conjugates

Chapter 6 Market Breakdown by Application

Drug Development and Discovery
Process of Rna-Based Drug Discovery
Design of Rnai Drugs
Sequence Optimization
Chemical Modification
Targeted Delivery
Therapeutic Application

Chapter 7 Market Breakdown by Route of Administration

Chapter 8 Market Breakdown by Molecules

Small Interfering Ribonucleic Acid
Antisense Oligonucleotide
Fomivirsen (Vitravene)
Mipomersen
Nusinersen (Spinraza)
Inotersen (Tegsedi)
Eteplirsen (Exondys 51)
Golodirsen (Vyondys 53)
Milasen: a Unique Personalized Medicine
Messenger Rna
Others
Aptamers
Micro Rna

Chapter 9 Market Breakdown by Therapeutic Area

Oncology
Rare and Genetic Diseases
Central Nervous System
Respiratory
Other Disease

Chapter 10 Market Breakdown by Region

North America
Europe
Asia-Pacific
Japan
South Korea
China
India
Australia
Rest of the World

Chapter 11 Environmental, Social and Governance in the Biotechnology Sector

Key Environmental, Social and Governance Issues in the Biotechnology Industry
Biotechnology Industry Environmental, Social and Governance Performance Analysis
Environmental Performance
Social Performance
Governance Performance
Consumer Perspective on Esg in Biotechnology
Case Study
Concluding Remarks

Chapter 12 Emerging Technologies and Developments

Drug Delivery to Lungs
Nanotechnology
Use of Artificial Intelligence and Machine Learning

Chapter 13 Clinical Trial and Patent Analysis

Clinical Trials Analysis
Patent Analysis

Chapter 14 Mergers and Acquisitions and Funding Outlook

Start-Up Funding in Nucleic Acid Delivery Technology

Chapter 15 Competitive Intelligence

For more information about this report visit https://www.researchandmarkets.com/r/a9jkg9

Source: BCC Research

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