Amgen To Present Data From Four Phase 2 Studies At Upcoming American Heart Association Scientific Sessions 2012

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Nov 02, 2012, 09:17 ET

THOUSAND OAKS, Calif., Nov. 2, 2012 /PRNewswire/ -- Amgen (NASDAQ:AMGN) will present data from four Phase 2 trials of AMG 145, an investigational fully human monoclonal antibody directed against PCSK9, a protein that reduces the liver's ability to remove low density lipoprotein cholesterol (LDL-C), or "bad" cholesterol from the blood, at the upcoming American Heart Association (AHA) Scientific Sessions 2012.

Selected abstracts of interest that will be presented at the meeting include:

Reduction of LDL-C with PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder (RUTHERFORD): Results from a Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial
Late-Breaking Clinical Trials, Monday, Nov. 05, 10:50 a.m. – 11:00 a.m. (Hall G)
Goal Achievement after Utilizing an Anti-PCSK9 in Statin Intolerant Subjects (GAUSS): Results from a Randomized, Double-blind, Placebo controlled Study
Late-Breaking Clinical Trials, Monday, Nov. 05, 11:00 a.m. – 11:10 a.m. (Hall G)
LAPLACE-TIMI 57 Primary Results
Clinical Science: Special Reports, Tuesday, Nov. 06, 7:45 a.m. – 7:55 a.m. (Petree Hall D)
Efficacy and Safety of a Fully Human Monoclonal Antibody Against PCSK9 as Monotherapy for Hypercholesterolemia: Results from the MENDEL Study, a Global Phase 2 Trial of AMG 145
Clinical Science: Special Reports, Tuesday, Nov. 06, 7:55 a.m. – 8:05 a.m. (Petree Hall D)

About Amgen

Amgen discovers, develops, manufactures and delivers innovative human therapeutics. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the new science's promise by bringing safe, effective medicines from lab to manufacturing plant to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, bone disease and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people's lives. For more information, visit www.amgen.com and follow us on www.twitter.com/amgen.

Forward-Looking Statements

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CONTACT: Amgen, Thousand Oaks
Christine Regan, 805-559-0718 (media)
Arvind Sood, 805-447-1060 (investors)

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SOURCE Amgen