RMANJ To Present 24 Abstracts At The American Society for Reproductive Medicine Annual Meeting

BASKING RIDGE, N.J., Oct. 16, 2012 /PRNewswire/ -- Reproductive Medicine Associates of New Jersey (http://www.rmanj.com) will be presenting 24 abstracts at the upcoming American Society for Reproductive Medicine Annual Meeting to be held October 20-24, 2012, in San Diego, California.

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"We are very proud of the outstanding research conducted by the team at RMANJ.  This year, our research covers important topics in reproductive medicine ranging from the continued validation of genetic screening to the reality of single embryo transfer in IVF," said Richard T. Scott, Jr., M.D., F.A.C.O.G., H.C.L.D., founding partner of RMANJ.  "We are particularly excited to present the findings from our BEST Trial, the first well-controlled clinical trial comparing IVF pregnancy rates in a group of women receiving a single embryo transfer with comprehensive chromosome screening compared to a group receiving traditional morphology-based double embryo transfer.  These findings are poised to fundamentally change the way IVF is practiced."

2012 ASRM ABSTRACT LIST

Monday, October 22, 2012

Morphology plus ploidy: a prospective study comparing traditional morphology-based selection for single embryo transfer (SET) with comprehensive chromosome screening (CCS) results (O-57)
Eric Forman
Oral – Monday 5:15-5:30 p.m. Outcome Predictors-Lab: ART

Comparison of clinical outcomes between genetically similar groups of in vitro fertilization patients (O-83)
Shefali Shastri
Oral – Monday 5:45-6:00 p.m. Reproductive Endocrinology: Research

Tuesday, October 23, 2012

Blastocyst euploid selective transfer (BEST): an RCT of comprehensive chromosome screening-single embryo transfer (CCS-SET) vs. double embryo transfer (DET) – equivalent pregnancy rates, eliminates twins (O-161)
Eric Forman
Oral – Tuesday 4:15-4:30 p.m. Outcome Predictors-Clinical: ART

Trophectoderm is predictive of the inner cell mass and newborn mitochondrial DNA mutation load (O-194)
Nathan Treff
Oral – Tuesday 4:30-4:45 p.m. Reproductive Biology: Human Studies

Development and validation of next-generation sequencing (NGS) based PGD (O-178)
Anastasia Fedick
Oral – Tuesday 4:30-4:45 p.m. Preimplantation Genetic Diagnosis

Embryos whose polar bodies had a reciprocal chromosomal abnormality are almost always euploid: a result of correction of premature separation of sister chromatids (PSSC) (O-203)
Eric Forman
Oral – Tuesday 4:55-5:15 p.m. Reproductive Endocrinology: Fellows Research

Development of a novel next-gen sequencing (NGS) methodology for accurate characterization of genome-wide mitochondrial heteroplasmy in human embryo (O-196)
Kathleen Hong
Oral – Tuesday 5:00-5:15 p.m. Reproductive Biology: Human Studies

Trophectoderm (TE) biopsy, blastocyst vitrification, and simultaneous single gene disorder (SGD) and comprehensive chromosome screening (CCS) results in excellent ongoing pregnancy rates (P-76)
Eric Forman
Poster Session – Tuesday: Preimplantation Genetic Diagnosis

Optimizing the temperature for embryo culture in IVF: a randomized controlled trial (RCT) comparing standard culture temperature of 37C to the reduced more physiologic temperature of 36C (P-189)
Kathleen Hong
Poster Session – Tuesday: Embryo Culture

Telomere DNA length is not predictive of embryonic reproductive potential (P-177)
Ndeye-Aicha Gueye
Poster Session – Tuesday: Embryo Biology

Development of a 4 hour protocol for simultaneous single gene disorder (SGD) and comprehensive chromosomal aneuploidy screening (CCS) from a single trophectoderm (TE) biopsy (P-74)
Russell Pepe
Poster Session – Tuesday: Preimplantation Genetic Diagnosis

Single nucleotide polymorphism (SNP) microarrays (MA) may be valuable in detecting small genomic imbalances and distinguishing balanced from normal embryos for carriers of reciprocal translocations (P-65)
Marie Werner
Poster Session – Tuesday: Genetic Counseling

Quantitative real-time (q) PCR based embryonic DNA fingerprinting successfully distinguishes sibling human embryos: a practical tool for biomarker development (P-97)
Xin Tao
Poster Session – Tuesday: Preimplantation Genetic Diagnosis

Wednesday, October 24, 2012

Oocyte vitrification does not result in a decrement in mitochondrial DNA (mtDNA) copy number in resulting embryos: a paired randomized controlled trial (RCT) (O-300)
Eric Forman
Oral – Wednesday 4:00-4:15 p.m. Cryopreservation and Frozen Embryo Transfer – Laboratory/Basic: ART

Analysis of the earliest appearance of cell free fetal DNA in maternal circulation (O-372)
Heather Garnsey
Oral – Wednesday 4:00-4:15 p.m. Reproductive Endocrinology: Clinical

Variation within the normal range in fragile x mental retardation 1 (FMR1) gene CGG repeat number is not predictive of ovarian responsiveness during IVF (O-352)
Marie Werner
Oral – Wednesday 5:00-5:15 p.m. Ovarian Stimulation: ART

GnRH antagonist (GnRHant) does not have a negative effect on endometrial receptivity: a comparison of outcomes of high quality euploid blastocysts in fresh antagonist vs. agonist cycles (O-353)
Kathleen Hong
Oral – Wednesday 5:15-5:30 p.m. Ovarian Stimulation: ART

Trophectoderm (TE) biopsy for aneuploidy screening results in lower initial hCG levels with altered predictive values: low initial levels still have high delivery rates and normal pregnancy outcomes (O-378)
Meir Olcha
Oral – Wednesday 5:30-5:45 p.m. Reproductive Endocrinology: Clinical

FMR1 gene CGG repeat number variation within the normal range is not predictive of embryonic aneuploidy rate (AR) in IVF (P-321)
Kathleen Hong
Poster Session – Wednesday: Ovarian Function

Monozygotic twinning (MZT) rates increase with embryo cohort quality and are not directly related to cleavage (CL) stage or blastocyst (BL) stage transfer (P-563)
Kathleen Hong
Poster Session – Wednesday: Outcome Predictors-Lab: ART

Cohort aneuploidy rates are not predictive of sustained implantation rate of euploid blastocysts: give that blastocyst a chance! (P-578)
Kathleen Hong
Poster Session – Wednesday: ART-In Vitro Fertilization

Among patients of similar ages, a low serum anti-mullerian hormone (AMH) does not predict a higher incidence of aneuploidy in embryos tested with comprehensive chromosomal screening (CCS) (P-490)
Thomas Molinaro
Poster Session – Wednesday: ART-Clinical

Embryology training for reproductive endocrinology (RE) fellows in the clinical human embryology laboratory: comprehensive training on actual clinical cases with excellent patient outcomes (P-587)
Richard Scott
Poster Session – Wednesday: ART-In Vitro Fertilization

Body mass index (BMI) does not impact endometrial receptivity in fresh IVF cycles: evaluation of implantation rates (IR) and ongoing pregnancy rates (PR) following the transfer of euploid blastocysts (P-591)
Marie Werner
Poster Session – Wednesday: ART-In Vitro Fertilization

Joint Abstracts with CCRM

The incidence of chromosome errors differs at the preimplantation stage from that observed later in pregnancy (O-34)
Shane Mitchell
Oral – Monday 4:15-6:15 p.m. Genetic Counseling

Time lapse observation of embryo development identifies later stage morphology based parameters associated with blastocyst quality but not chromosome constitution (O-98)
John Stevens
Oral – Monday 4:15-6:15 p.m. Reproductive Laboratory Technology

Comprehensive chromosome screening (CCS) with vitrification results in improved clinical outcome in women >35 years: a randomized control trial (O-1)
William Schoolcraft
Oral – Monday 11:15-1:00 p.m. Scientific Program Prize Paper Oral Abstract Presentations I

About Reproductive Medicine Associates of New Jersey
Reproductive Medicine Associates of New Jersey have pioneered and successfully implemented a cutting-edge technology, known as Comprehensive Chromosome Screening (CCS) to more accurately detect healthy embryos that will lead to successful pregnancies and ultimately healthy babies. Other centers have attempted similar testing methods, but RMANJ is the only fertility center in the world to have developed a system of unprecedented accuracy, fully validated through years of rigorous clinical research. RMANJ's Comprehensive Chromosome Screening offers advanced embryo selection with extreme accuracy by detecting and avoiding use of embryos with chromosomal abnormalities prior to transfer and pregnancy.

The fertility experts at RMANJ have among the highest IVF success rates in the country. Since 1999, they have helped bring more than 20,000 babies to loving families.  In addition to serving as the Division of Reproductive Endocrinology at Robert Wood Johnson University Medical School in New Brunswick, NJ, the practice has seven locations in New Jersey. For more information please call RMANJ at 973-656-2089, or visit www.rmanj.com.

SOURCE Reproductive Medicine Associates of New Jersey

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