MediPoint: Knee Replacement - Global Analysis and Market Forecasts

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MediPoint: Knee Replacement - Global Analysis and Market Forecasts

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MediPoint: Knee Replacement - Global Analysis and Market Forecasts

Summary

The current knee replacement market is a crowded space, with an increasing number of companies offering a myriad of partial, primary/total, and revision prostheses to meet orthopedic surgeons' demands in the management of knee diseases, primarily osteoarthritis. Worldwide, the primary/total knee segment represents about 80–90% of the entire knee market, with the remainder being partial knee and revision knee. Overall, clinical data show that short- to medium-term survivorship is excellent after almost all common types of knee replacement, regardless of fixation, constraint, and bearing type. Future competition among vendors will be more likely to center on the instrumentation and the ancillary equipment, such as patient-specific instruments, navigation systems, and robotic systems.

The expanding patient population for surgical treatments, widespread appreciation of the clinical efficacy of knee replacements, and technological advancement from the supply side have all contributed to a stable increase in the procedure volume of knee replacements. However, the recent global economic downturn has resulted in intensified budget constraints in the US and EU (European Union) healthcare systems, with a particular focus on limiting spending on high-volume surgeries. As the downward pricing pressures continuously offset the rise in procedure volume, and cost-containment initiatives directly impact the adoption of premium-priced devices and technologies, the market revenue is only going to grow at a slower pace.

Highlights

Key Questions Answered

- While medical innovations that cater to younger, more physically active patients have led to an expanded adoption of knee replacement in treating degenerative knee diseases, the modest growth in procedure volume is largely offset by the lingering softness in the global economy. How are governments' cost-containment measures affecting the procedure volume and market revenue of knee replacement?
- In the years to come, launching and marketing a comprehensive knee portfolio with a clear value proposition will remain critical to companies' success as they jockey for market position. What are the most important product features and designs surgeons like about current systems? What features would they like to see in future product iterations?
- Orthopedic surgeons hold varied opinions upon adopting computer-assisted technologies in knee replacement surgeries. What are the current adoption levels of these technologies in different countries? What are the major drivers behind companies' current focus on patient-specific instruments?
- Orthopedic giants dominate more than 80% of the global knee market. Who are the current and future players in this market? How will small- to mid-cap companies leverage their portfolios to navigate the competitive landscape?
- As the US healthcare system is under increasing pressure to create efficiencies across the entire supply chain, there are a growing number of newcomers bringing in the concept of 'generic' implants. What are surgeons' attitudes about these generic implants? How will the influx of generic implants impact the global knee space?

Reasons to buy

- "What Do Physicians Think" quotes provide a unique insight into how healthcare professionals are reacting to events within the industry, and what their responses could mean for industry strategists. This information is essential for all strategic decision makers in every organization allowing them to act on high quality information.

Table of Contents

1 Table of Contents 7
1.1 List of Tables 14
1.2 List of Figures 20
2 Introduction 24
2.1 Catalyst 25
2.2 Related Reports 25
3 Disease Overview 26
3.1 Anatomy and Physiology 26
3.2 Pathophysiology 28
3.2.1 Overview 28
3.2.2 Primary Osteoarthritis 28
3.2.3 Rheumatoid Arthritis 29
3.2.4 Post-Traumatic Arthritis 30
3.2.5 Avascular Necrosis 30
3.3 Clinical Presentation 31
3.3.1 Diagnosis 31
3.4 Clinical Outcomes 32
3.4.1 Overview 32
3.4.2 Conservative Treatments 32
3.4.3 Joint-Preserving Treatments 34
3.4.4 Joint Replacement 36
3.5 Economic Impact 47
3.5.1 United States 48
3.5.2 5EU 49
3.5.3 Asia-Pacific 50
3.5.4 South America 50
4 Industry Overview 51
4.1 Procedural Trends 51
4.1.1 United States 51
4.1.2 5EU 55
4.1.3 Asia-Pacific 61
4.1.4 South America 65
4.2 Market Access 68
4.2.1 United States 68
4.2.2 5EU 84
4.2.3 Asia-Pacific 98
4.2.4 South America 107
4.3 Regulatory Issues/Recalls 114
4.3.1 DePuy Orthopaedic's Diaphyseal Sleeve Components of the Limb Preservation System (LPS) 114
4.3.2 Stryker's ShapeMatch Cutting Guides 114
4.3.3 B. Braun's Columbus Total Knee System's Cementless Version 115
4.3.4 Smith & Nephew's Journey Uni Tibial Insert, Right Medial/Left Lateral 115
4.4 Mergers and Acquisitions/Key Partnerships 116
4.4.1 Stryker's Acquisition of MAKO Surgical 116
4.4.2 MicroPort Medical B.V.'s Acquisition of Wright Medical's OrthoRecon Business 116
4.4.3 Stryker's Extension of Co-Marketing Agreement with OrthoSensor 117
4.4.4 Blue Belt Technologies' Co-Marketing Agreement with DJO Surgical 117
4.4.5 Biomet and OrthoSensor Enter Into Co-Promotion Partnership 117
4.4.6 Italian Consortium 2IL Orthopaedics Acquires Corin Group 118
4.4.7 Smith & Nephew Acquires LifeModeler, Inc. (LMI) 118
4.5 Market Drivers, Opportunities, and Barriers 119
4.5.1 Market Drivers 119
4.5.2 Market Opportunities 124
4.5.3 Market Barriers 130
5 Competitive Assessment 135
5.1 Overview 135
5.2 Global Market Share 137
5.3 B. Braun 138
5.3.1 Primary Knee Replacement 138
5.3.2 Partial Knee Replacement 140
5.3.3 Revision Knee Replacement 141
5.3.4 SWOT Analysis 141
5.4 Biomet 142
5.4.1 Primary Knee Replacement 142
5.4.2 Partial Knee Replacement 145
5.4.3 Revision Knee Replacement 146
5.4.4 SWOT Analysis 147
5.5 DePuy Synthes 148
5.5.1 Primary Knee Replacement 148
5.5.2 Partial Knee Replacement 153
5.5.3 Revision Knee Replacement 154
5.5.4 SWOT Analysis 155
5.6 DJO Surgical 156
5.6.1 Primary Knee Replacement 156
5.6.2 Partial Knee Replacement 159
5.6.3 Revision Knee Replacement 159
5.6.4 SWOT Analysis 160
5.7 Exactech 161
5.7.1 Primary Knee Replacement 161
5.7.2 Partial Knee Replacement 162
5.7.3 Revision Knee Replacement 163
5.7.4 SWOT Analysis 163
5.8 Smith & Nephew 164
5.8.1 Primary Knee Replacement 164
5.8.2 Partial Knee Replacement 168
5.8.3 Revision Knee Replacement 169
5.8.4 SWOT Analysis 170
5.9 Stryker 171
5.9.1 Primary Knee Replacement 171
5.9.2 Partial Knee Replacement 174
5.9.3 Revision Knee Replacement 175
5.9.4 SWOT Analysis 176
5.10 Wright Medical (MicroPort) 177
5.10.1 Primary Knee Replacement 177
5.10.2 Revision Knee Replacement 179
5.10.3 SWOT Analysis 180
5.11 Zimmer 181
5.11.1 Primary Knee Replacement 181
5.11.2 Partial Knee Replacement 187
5.11.3 Revision Knee Replacement 187
5.11.4 SWOT Analysis 189
6 Unmet Needs 190
6.1 Availability of Long-Term Clinical Data 190
6.2 Complete Knee Platform 192
6.3 Need for Cost-Containment 194
6.4 Training for Computer Navigation Technologies 195
6.5 Continued Innovations in Instrumentation 197
6.6 Advanced Materials 198
6.7 Implants for Metal-Sensitive Patients 199
6.8 National Joint Registry 200
7 Pipeline Products 202
7.1 Overview 202
7.2 Biomet's Vanguard XP Total Knee System 202
7.3 Corentec's Lospa Total Knee System 203
7.4 NovoSource's NovoKnee 203
7.5 Pipeline Orthopedics' NEO PS Knee System 203
7.6 Bonovo Orthopedics' JMM Total Knee System 203
7.7 Corin Group's Unity Knee Systems 204
7.8 Kinamed's GEM Total Knee System 204
7.9 Emerge Medical 204
8 Current and Future Players 205
8.1 Trends in Corporate Strategy 205
8.2 Established Players 207
8.2.1 B. Braun 207
8.2.2 Biomet 210
8.2.3 Corin Group 214
8.2.4 DePuy Synthes 217
8.2.5 DJO Global 221
8.2.6 Exactech 224
8.2.7 Lima Corporate 227
8.2.8 Medacta 229
8.2.9 Smith & Nephew 231
8.2.10 Stryker 235
8.2.11 Waldemar LINK 239
8.2.12 Wright Medical Group (MicroPort) 242
8.2.13 Zimmer Holdings 246
8.2.14 Other Established Players 250
8.3 Emerging Players 251
8.3.1 Blue Belt Technologies 251
8.3.2 ConforMIS 254
8.3.3 MAKO Surgical 257
8.3.4 OmniLife science 260
8.3.5 Other Emerging Players 263
9 Market Outlooks 264
9.1 Overview 264
9.2 US 269
9.3 France 272
9.4 Germany 275
9.5 Italy 278
9.6 Spain 280
9.7 United Kingdom 282
9.8 Japan 285
9.9 Brazil 288
9.10 China 291
9.11 India 294
10 Appendix 297
10.1 Abbreviations 297
10.2 Bibliography 300
10.3 Report Methodology 319
10.3.1 Overview 319
10.3.2 Coverage 319
10.3.3 Secondary Research 320
10.3.4 Forecasting Methodology 321
10.3.5 Primary Research - Key Opinion Leader Interviews 322
10.3.6 Expert Panel Validation 322
10.4 Physicians and Specialists Included in This Study 323
10.5 Physician Survey 325
10.6 About the Authors 326
10.6.1 Analysts 326
10.6.2 Bonnie Bain, Ph.D., Global Head of Healthcare 327
10.7 About MediPoint 328
10.8 About GlobalData 328
10.9 Disclaimer 328

List of Tables

Table 1: Risk Factors for Primary OA of the Knee 29
Table 2: Common Clinical Symptoms of Knee Arthritis 31
Table 3: Common Reasons for Failed Knee Implants 43
Table 4: Advantages of CAS 45
Table 5: Direct, Indirect, and Intangible Costs of Arthritis 47
Table 6: Medicare Reimbursement Coding Guide for Knee Arthroplasty, 2013 80
Table 7: Medicare National Average Reimbursement Rates for Knee Arthroplasty, 2012-2013 81
Table 8: Differences Between US FDA Approval and EU CE-Marking 84
Table 9: Common Reasons for Revision After Total and Partial Knee Replacement 131
Table 10: Product Profile - Columbus Total Knee System 139
Table 11: Product Profile - e.motion Total Knee System 140
Table 12: Product Profile - univation Unicondylar Knee System 140
Table 13: Product Profile - B. Braun's Revision Knee Replacement Systems 141
Table 14: SWOT Analysis - B. Braun's Knee Portfolio 141
Table 15: Product Profile - Vanguard Complete Knee System 143
Table 16: List of Select Clinical Studies - Vanguard Complete Knee System 143
Table 17: Product Profile - AGC Total Knee System 144
Table 18: List of Select Clinical Studies - AGC Total Knee System 145
Table 19: Product Profile - Biomet's Partial Knee Replacement Systems 146
Table 20: Product Profile - Biomet's Revision Knee Replacement Systems 146
Table 21: Select Clinical Study - Biomet's Revision Knee Replacement Systems 147
Table 22: SWOT Analysis - Biomet's Knee Portfolio 147
Table 23: Product Profile - LCS Complete Knee Systems 149
Table 24: List of Select Clinical Studies - LCS Complete Knee System 149
Table 25: Product Profile - Sigma Knee System 151
Table 26: List of Select Clinical Studies - Sigma Knee System 151
Table 27: Product Profile - Attune Knee System 152
Table 28: List of Select Clinical Studies - Attune Knee System 153
Table 29: Product Profile - Sigma HP Partial Knee System 153
Table 30: Product Profile - DePuy's Revision Knee Replacement Systems 154
Table 31: List of Select Clinical Studies - DePuy's Revision Knee Replacement Systems 155
Table 32: SWOT Analysis - DePuy's Knee Portfolio 155
Table 33: Product Profile - Movation Knee System 156
Table 34: Product Profile - 3D Knee System 157
Table 35: Product Profile - Foundation Knee System 158
Table 36: Product Profile - EPIK Knee System 159
Table 37: Product Profile - Foundation Revision Knee System 159
Table 38: SWOT Analysis - DJO's Knee Portfolio 160
Table 39: Product Profile - Optetrak Knee System 162
Table 40: Product Profile - Optetrak Unicondylar Knee System 162
Table 41: Product Profile - Optetrack Constrained Condylar (CC) Knee System 163
Table 42: SWOT Analysis - Exactech's Knee Portfolio 163
Table 43: Product Profile - LEGION Knee System 165
Table 44: List of Select Clinical Studies - GENESIS II Total Knee System 165
Table 45: Product Profile - JOURNEY Knee System 167
Table 46: List of Select Clinical Studies - JOURNEY Knee System 167
Table 47: Product Profile - Smith & Nephew's Partial Knee Replacement Systems 168
Table 48: Product Profile - Smith & Nephew's Revision Knee Systems 169
Table 49: SWOT Analysis - Smith & Nephew's Knee Portfolio 170
Table 50: Product Profile - Triathlon Total Knee System 172
Table 51: List of Select Clinical Studies - Triathlon Total Knee System 172
Table 52: Product Profile - Scorpio Knee System 173
Table 53: Product Profile - Stryker's Partial Knee Replacement Systems 174
Table 54: Product Profile - Stryker's Revision Knee Replacement Systems 175
Table 55: Select Clinical Study - Stryker's Revision Knee Replacement System 175
Table 56: SWOT Analysis - Stryker's Knee Portfolio 176
Table 57: Product Profile - Advance Knee System 178
Table 58: Product Profile - Evolution Medial-Pivot Knee System 179
Table 59: Product Profile - Wright Medical's Revision Knee Replacement Systems 179
Table 60: SWOT Analysis - Wright Medical's Knee Portfolio 180
Table 61: Product Profile - NexGen Knee System 182
Table 62: List of Select Clinical Studies - NexGen Knee System 183
Table 63: Product Profile - Gender Solutions Knee Systems 184
Table 64: List of Select Clinical Studies - Gender Solutions Knee System 185
Table 65: Product Profile - Persona Knee System 186
Table 66: List of Select Clinical Studies - Persona Knee System 186
Table 67: Product Profile - Zimmer's Partial Knee Replacement Systems 187
Table 68: Product Profile - Zimmer's Revision Knee Replacement Systems 188
Table 69: SWOT Analysis - Zimmer's Knee Portfolio 189
Table 70: Pipeline Products in the Global Knee Replacement Market, 2013 202
Table 71: Company Profile - B. Braun 207
Table 72: Portfolio Assessment - B. Braun 208
Table 73: SWOT Analysis - B. Braun 209
Table 74: Company Profile - Biomet 211
Table 75: Portfolio Assessment - Biomet 212
Table 76: SWOT Analysis - Biomet 213
Table 77: Company Profile - Corin Group 214
Table 78: Portfolio Assessment - Corin Group 215
Table 79: SWOT Analysis - Corin Group 216
Table 80: Company Profile - DePuy Synthes 217
Table 81: Portfolio Assessment - DePuy Synthes 219
Table 82: SWOT Analysis - DePuy Synthes 220
Table 83: Company Profile - DJO Global 221
Table 84: Portfolio Assessment - DJO Global 222
Table 85: SWOT Analysis - DJO Global 223
Table 86: Company Profile - Exactech 224
Table 87: Portfolio Assessment - Exactech 225
Table 88: SWOT Analysis - Exactech 226
Table 89: Company Profile - Lima Corporate 227
Table 90: Portfolio Assessment - Lima Corporate 228
Table 91: SWOT Analysis - Lima Corporate 228
Table 92: Company Profile - Medacta 229
Table 93: Portfolio Assessment - Medacta 230
Table 94: SWOT Analysis - Medacta 230
Table 95: Company Profile - Smith & Nephew 232
Table 96: Portfolio Assessment - Smith & Nephew 233
Table 97: SWOT Analysis - Smith & Nephew 234
Table 98: Company Profile - Stryker 236
Table 99: Portfolio Assessment - Stryker 237
Table 100: SWOT Analysis - Stryker 238
Table 101: Company Profile - Waldemar LINK 239
Table 102: Portfolio Assessment - Waldemar LINK 240
Table 103: SWOT Analysis - Waldemar LINK 241
Table 104: Company Profile - Wright Medical Group 243
Table 105: Portfolio Assessment - Wright Medical Group 244
Table 106: SWOT Analysis - Wright Medical Group 245
Table 107: Company Profile - Zimmer Holdings 247
Table 108: Portfolio Assessment - Zimmer Holdings 248
Table 109: SWOT Analysis - Zimmer Holdings 249
Table 110: Other Established Players in the Global Knee Replacement Market, 2013 250
Table 111: Company Profile - Blue Belt Technologies 251
Table 112: Portfolio Assessment - Blue Belt Technologies 252
Table 113: SWOT Analysis - Blue Belt Technologies 253
Table 114: Company Profile - ConforMIS 254
Table 115: Portfolio Assessment - ConforMIS 255
Table 116: SWOT Analysis - ConforMIS 256
Table 117: Company Profile - MAKO Surgical 257
Table 118: Portfolio Assessment - MAKO Surgical 258
Table 119: SWOT Analysis - MAKO Surgical 259
Table 120: Company Profile - OMNIlife science 260
Table 121: Portfolio Assessment - OMNIlife science 261
Table 122: SWOT Analysis - OMNIlife science 262
Table 123: Other Emerging Players in the Global Knee Replacement Market, 2013 263
Table 124: Global Knee Replacement Market Sales Forecast ($m) in the 10MM, 2010-2019 264
Table 125: Global Primary Knee Replacement Market Sales Forecast ($m) in the 10MM, 2010-2019 267
Table 126: Global Partial Knee Replacement Market Sales Forecast ($m) in the 10MM, 2010-2019 268
Table 127: US Knee Replacement Market Sales Forecast ($m), 2010-2019 270
Table 128: France Knee Replacement Market Sales Forecast ($m), 2010-2019 272
Table 129: Germany Knee Replacement Market Sales Forecast ($m), 2010-2019 275
Table 130: Italy Knee Replacement Market Sales Forecast ($m), 2010-2019 278
Table 131: Spain Knee Replacement Market Sales Forecast ($m), 2010-2019 280
Table 132: UK Knee Replacement Market Sales Forecast ($m), 2010-2019 282
Table 133: Japan Knee Replacement Market Sales Forecast ($m), 2010-2019 285
Table 134: Brazil Knee Replacement Market Sales Forecast ($m), 2010-2019 288
Table 135: China Knee Replacement Market Sales Forecast ($m), 2010-2019 291
Table 136: India Knee Replacement Market Sales Forecast ($m), 2010-2019 294
Table 137: Abbreviations 297
Table 138: Physicians Surveyed, By Country 325

1.2 List of Figures
Figure 1: Schematic Diagram of Knee Anatomy 26
Figure 2: Unicompartmental Knee Replacement 37
Figure 3: Patellofemoral Knee Replacement 39
Figure 4: Bicompartmental Knee Replacement 40
Figure 5: CR and PS Designs 41
Figure 6: Knee Replacement Procedure Volume, US, 2010-2019 51
Figure 7: Partial Knee Replacement Procedure Volume, US, 2010-2019 52
Figure 8: Primary Knee Replacement Procedure Volume, US, 2010-2019 53
Figure 9: Revision Knee Replacement Procedure Volume, US, 2010-2019 54
Figure 10: Knee Replacement Procedure Volume, 5EU, 2010-2019 57
Figure 11: Partial Knee Replacement Procedure Volume, 5EU, 2010-2019 58
Figure 12: Primary Knee Replacement Procedure Volume, 5EU, 2010-2019 59
Figure 13: Revision Knee Replacement Procedure Volume, 5EU, 2010-2019 60
Figure 14: Knee Replacement Procedure Volume, APAC, 2010-2019 61
Figure 15: Partial Knee Replacement Procedure Volume, APAC, 2010-2019 62
Figure 16: Primary Knee Replacement Procedure Volume, APAC, 2010-2019 63
Figure 17: Revision Knee Replacement Procedure Volume, APAC, 2010-2019 64
Figure 18: Knee Replacement Procedure Volume, Brazil, 2010-2019 65
Figure 19: Partial Knee Replacement Procedure Volume, Brazil, 2010-2019 66
Figure 20: Primary Knee Replacement Procedure Volume, Brazil, 2010-2019 66
Figure 21: Revision Knee Replacement Procedure Volume, Brazil, 2010-2019 67
Figure 22: Adoption Trend for Total Knee Implants in the US, Fixed-Bearing vs. Mobile-Bearing, 2011-2015 72
Figure 23: Adoption Trend for Total Knee Implants in the US, Cruciate-Retaining vs. Cruciate-Sacrificing, 2011-2015 73
Figure 24: Adoption Trend for Revision Knee Implants in the US, 2011-2015 74
Figure 25: Adoption Trend for Computer-Assisted Technologies in the US, 2012 75
Figure 26: Medicare Payment Trend for Hip and Knee Replacements, 1985-2009 83
Figure 27: Adoption Trend for Total Knee Implants in the 5EU, Fixed-Bearing vs. Mobile-Bearing, 2011-2015 88
Figure 28: Adoption Trend for Total Knee Implants in the 5EU, Cruciate Retaining vs. Cruciate Sacrificing, 2011-2015 89
Figure 29: Adoption Trend for Revision Knee Implants in the 5EU, 2011-2015 90
Figure 30: Adoption Trend for Computer-Assisted Technologies in the 5EU, 2012 91
Figure 31: Adoption Trend for Total Knee Implants in APAC, Fixed-Bearing vs. Mobile-Bearing, 2011-2015 99
Figure 32: Adoption Trend for Total Knee Implants in APAC, Cruciate-Retaining vs. Cruciate-Sacrificing, 2011-2015 100
Figure 33: Adoption Trend for Revision Knee Implants in APAC, 2011-2015 101
Figure 34: Adoption Trend for Computer-Assisted Technologies in APAC, 2012 103
Figure 35: Adoption Trend for Total Knee Implants in Brazil, Fixed-Bearing vs. Mobile-Bearing, 2011-2015 108
Figure 36: Adoption Trend for Total Knee Implants in Brazil, Cruciate-Retaining vs. Cruciate- Sacrificing, 2011-2015 109
Figure 37: Adoption Trend for Revision Knee Implants in Brazil, 2011-2015 110
Figure 38: Adoption Trend for Computer-Assisted Technologies in Brazil, 2012 111
Figure 39: Global Knee Replacement Market, Competitive Landscape by Sales Revenue, 2012 137
Figure 40: Columbus Total Knee System 138
Figure 41: e.motion Total Knee System 139
Figure 42: Vanguard Complete Knee System 142
Figure 43: AGC Total Knee System 144
Figure 44: LCS Complete Knee System 148
Figure 45: Sigma Knee System 150
Figure 46: Attune Knee System 152
Figure 47: Movation Knee System 156
Figure 48: 3D Knee System 157
Figure 49: Foundation Knee System 158
Figure 50: Optetrak Logic Knee System 161
Figure 51: GENESIS II Total Knee System 164
Figure 52: Journey Knee System 166
Figure 53: Triathlon Total Knee System 171
Figure 54: Scorpio Knee System 173
Figure 55: Advance Knee System 177
Figure 56: Evolution Medial-Pivot Knee System 178
Figure 57: NexGen Knee System 181
Figure 58: Gender Solutions' NexGen High-Flex Knee 184
Figure 59: Persona Knee System 186
Figure 60: Level of Impact of the Availability of Long-Term Clinical Data Upon Decision-Making (n=103) 191
Figure 61: Level of Impact of a Complete Knee System Upon Decision-Making (n=103) 192
Figure 62: Global Knee Replacement Market Sales Forecast ($m) in the 10MM, 2010-2019 265
Figure 63: Global Knee Replacement Market by Major Market, 2012 and 2019 266
Figure 64: Global Primary Knee Replacement Market Sales Forecast ($m) in the 10MM, 2010-2019 267
Figure 65: Global Partial Knee Replacement Market Sales Forecast ($m) in the 10MM, 2010-2019 268
Figure 66: US Knee Replacement Market Sales Forecast ($m), 2010-2019 270
Figure 67: US Primary Knee Replacement Market Segmentation by Type, 2012 and 2019 271
Figure 68: France Knee Replacement Market Sales Forecast ($m), 2010-2019 273
Figure 69: France Primary Knee Replacement Market Segmentation by Type, 2012 and 2019 274
Figure 70: Germany Knee Replacement Market Sales Forecast ($m), 2010-2019 276
Figure 71: Germany Primary Knee Replacement Market Segmentation by Type, 2012 and 2019 277
Figure 72: Italy Knee Replacement Market Sales Forecast ($m), 2010-2019 278
Figure 73: Italy Primary Knee Replacement Market Segmentation by Type, 2012 and 2019 279
Figure 74: Spain Knee Replacement Market Sales Forecast ($m), 2010-2019 280
Figure 75: Spain Primary Knee Replacement Market Segmentation by Type, 2012 and 2019 281
Figure 76: UK Knee Replacement Market Sales Forecast ($m), 2010-2019 282
Figure 77: UK Primary Knee Replacement Market Segmentation by Type, 2012 and 2019 283
Figure 78: UK Primary Knee Replacement Competitive Landscape, 2011 284
Figure 79: UK Partial Knee Replacement Competitive Landscape, 2011 284
Figure 80: Japan Knee Replacement Market Sales Forecast ($m), 2010-2019 286
Figure 81: Japan Primary Knee Replacement Market Segmentation by Type, 2012 and 2019 287
Figure 82: Brazil Knee Replacement Market Sales Forecast ($m), 2010-2019 289
Figure 83: Brazil Primary Knee Replacement Market Segmentation by Type, 2012 and 2019 290
Figure 84: China Knee Replacement Market Sales Forecast, 2010-2019 292
Figure 85: China Primary Knee Replacement Market Segmentation by Type, 2012 and 2019 293
Figure 86: India Knee Replacement Market Sales Forecast ($m), 2010-2019 295
Figure 87: India Primary Knee Replacement Market Segmentation by Type, 2012 and 2019 296

Companies Mentioned

B. Braun
Biomet
Corin Group
DePuy Synthes
DJO Global
Exactech
Lima Corporate
Medacta
Smith & Nephew
Stryker
Waldemar LINK
Wright Medical Group (MicroPort)
Zimmer Holdings
Other Established Players
erging Players
Blue Belt Technologies
ConforMIS
MAKO Surgical
OmniLife science