Global Deep Brain Stimulation Devices Industry

News provided by

Nov 18, 2015, 12:45 ET

NEW YORK, Nov. 18, 2015 /PRNewswire/ -- This report analyzes the worldwide markets for Deep Brain Stimulation Devices in US$ Thousand. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World. Annual estimates and forecasts are provided for the period 2014 through 2020. Also, a seven-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs. The report profiles 14 companies including many key and niche players such as -

Aleva Neurotherapeutics SA
Boston Scientific Corp.
Deep Brain Innovations, LLC
Medtronic, plc
St. Jude Medical, Inc.

Read the full report: http://www.reportlinker.com/p03180735-summary/view-report.html

I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations I-1 Disclaimers.............. I-2 Data Interpretation & Reporting Level I-2 Quantitative Techniques & Analytics I-3 Product Definitions and Scope of Study I-3 DBS Devices.............. I-3 Implantable Pulse Generator (IPG) I-3 The Extension.............. I-4 Leads/Electrodes..............I-4 Other Devices.............. I-4 Programmers.............. I-4 Accessories.............. I-4

II. EXECUTIVE SUMMARY

1. INDUSTRY OVERVIEW.............. II-1 A Foreword.............. II-1 Introduction to Deep Brain Stimulation Procedure & Devices II-1 Deep Brain Stimulation - Then and Now II-2 Sizing the Market for DBS Devices II-3 Recent Innovations and the Way Ahead II-3

2. MARKET DYNAMICS.............. II-5 Burgeoning Global Population Offers Significant Growth Opportunities.............. II-5 Table 1: Top 25 Countries Worldwide in Terms of Population (2010 & 2013) (includes corresponding Graph/Chart) II-5 Aging Population and Rising Disease Prevalence: The Cornerstone for DBS..............II-6 Table 2: Global Population Statistics for 65+ Age Group (2014) (includes corresponding Graph/Chart) II-7

Table 3: Elderly Population (65+ Years) Worldwide by Geographic Region on the Basis of Economic Status (2000 & 2025): % of Total Population for More Developed Countries, Less Developed Countries and Least Developed Countries (includes corresponding Graph/Chart) II-8 Increasing Healthcare Spending in Emerging Markets: Opportunities in Store..............II-8 Table 4: Healthcare Spending as % of GDP in Select Countries (2013) (includes corresponding Graph/Chart) II-9 Novel Applications Bode Tremendous Prospects II-9 Technical Advancements Aid in Progress of DBS II-10 Questions Arise on the Current Pace of Innovation II-10 Closed-Loop Functionality Gaining Favor over Open Loop in Neurostimulation.............. II-11 Investigational DBS Device Inches towards Closed-Loop Functionality.............. II-12 Closed-Loop Stimulation - A Potential Solution for Gait Disturbances in DBS Treated PD Patients II-13 Steering Brain Stimulation - An Emerging Concept in DBS II-13 Novel Investigational Leads Target Selective and Fractional Stimulation.............. II-14 Novel Electrode Configurations Aid in Localization and Side Effect Reduction.............. II-14 Nanotechnology - The Future of DBS Electrodes II-15 On-Demand Stimulators Promise to Contribute to Superior Therapeutic Outcomes..............II-15 Advances in Programming Promise Ease of Treatment II-16 Visual Depiction of Electrical Field Comes to the Aid of Programming.............. II-16 Device Programmability Gains Precedence in Device Choice II-17 Brain Imaging - Gaining Prominence in DBS II-17 Novel Imaging Techniques Come to the Fore II-17 New DBS Technique Promises Superior Outcomes II-17 Lack of Large Scale Study Results Subdue Asleep DBS; for Now II-18 Concerns Remain Afloat - Affecting Adoption II-19 Hardware-related Infections - A Major Concern II-20 Battery Life - A Bone of Contention for DBS II-20

3. TARGETED INDICATIONS FOR DBS..............II-21 Parkinson's Disease - The Largest Application Market for DBS II-21 A Note on Incidence and Prevalence of Parkinson's Disease II-22 Table 5: Global Prevalence of Parkinson's Disease (2014): Number of Patients Affected in Thousands for Select Countries/Regions (includes corresponding Graph/Chart) II-22 Research Suggests Greater Benefits of DBS in Parkinson's II-22 DBS - A Highly Effective Therapy for Essential Tremor II-23 Incidence and Prevalence of Essential Tremor II-23 DBS in Dystonia.............. II-23 Clinical Evidence of DBS in Dystonia: An Overview of Results from Select Clinical Studies and Meta-Analyses II-24 Dystonia Patient Selection Criteria for DBS II-25 DBS in OCD.............. II-26 DBS in Epilepsy Treatment..............II-26 Table 6: Global Prevalence of Epilepsy (2014): Number of Patients Affected in Thousands for Select Countries/Regions (includes corresponding Graph/Chart) II-27 DBS in Tourette Syndrome - Research Progress So Far II-27 Clinical Evidence of DBS in Tourette Syndrome: An Overview of Results from Select Clinical Studies and Meta-Analyses II-28 Paucity of Effective Drugs Drives Shift in Psychiatric Disorder Treatment.............. II-30 Multiple Possible Targets Marr Progress of DBS in Depression Treatment.............. II-30 Overview of Select Studies on DBS in Depression Treatment II-31 SCC - A Promising Target for Stimulation in Depression II-32 Eating Disorders - A Note on Potential of DBS II-32 DBS in Obesity - Animal Models Show Promise II-33 Anorexia Treatment - Where Does DBS Stand? II-33 DBS in Dementia Treatment - Animal Studies Bode Well for Efficacy in Humans.............. II-34 Prospects of DBS in Chronic Pain Management II-34

4. COMPETITIVE LANDSCAPE..............II-35 Leading Players.............. II-35 A Comparison of DBS Devices on the Market II-36 Timeline for Approvals of Major DBS Systems by Indication in US and EU.............. II-36 Player Strategies to Market - An Overview II-37 Timeline for Medtronic DBS Therapy II-37

5. PRODUCT OVERVIEW.............. II-39 Deep Brain Stimulation - An Overview II-39 A Brief Note on Birth and Evolution of DBS II-39 Devices in Deep Brain Stimulation II-40 Components of DBS System..............II-40 Implantable Pulse Generator (IPG) II-40 The Extension.............. II-40 Leads/Electrodes..............II-40 Other Products used in DBS Procedures II-40 Programmers.............. II-40 Accessories.............. II-40 DBS Procedure - A Brief Overview II-41 DBS Placement and Calibration..............II-41 Common Lead Targets for Select Neurological and Psychiatric Conditions in DBS.............. II-42 A Peek into Indications of DBS and Other Uses II-42 DBS Complications.............. II-42 A Gist of Common Complications Associated with DBS II-43

6. PRODUCT APPROVALS/INTRODUCTIONS II-44 Medtronic Obtains EU Clearance for Full-Body MR Conditional DBS Systems.............. II-44 Boston Scientific Obtains CE Mark for Vercise™ DBS System for Treating Tremor.............. II-44 Boston Scientific Obtains CE Mark for Vercise™ DBS System for Dystonia Treatment.............. II-44 St. Jude Medical Obtains CE Mark Approval for its DBS Systems in Dystonia Treatment..............II-44 EBS Technologies Secures CE Mark Approval for Next Wave DBS System.............. II-44 Boston Scientific Secures CE Mark Approval for GUIDE™ DBS Visualization System..............II-45 Boston Scientific Obtains CE Mark for Vercise™ DBS System for Parkinson's Disease..............II-45

7. RECENT INDUSTRY ACTIVITY..............II-46 Boston Scientific and Brainlab Team Up for DBS Therapy II-46 Medtronic to Refile for FDA Approval for its DBS System in Epilepsy Treatment.............. II-46 Medtronic Publishes Positive Results from SANTE Trial Evaluating DBS in Epilepsy..............II-46 Kelyniam Takes Over MED-ALLY..............II-46 Medtronic Acquires Sapiens SBS II-46 Boston Scientific Publishes Interim Results from VANTAGE Trial Evaluating Vercise DBS System for Parkinson's Disease II-47 Boston Scientific Publishes Positive Results from CUSTOM DBS Clinical Study on Vercise™ DBS System II-47 Aleva Publishes Positive Results from Intraoperative Study using directSTIM™ Directional Lead II-47 Boston Scientific Commences New Clinical Trial for its DBS System in Parkinson's Disease Treatment II-47 Medtronic Announces First Research Implant of Activa® PC+S DBS System in US.............. II-47 Functional Neuromodulation Obtains FDA Clearance to Expand DBS Study for Alzheimer's..............II-48 Venture Firm NDI Medical Commences New Portfolio Company Deep Brain Innovations, LLC..............II-48

8. FOCUS ON SELECT PLAYERS..............II-49 Aleva Neurotherapeutics SA (Switzerland) II-49 Boston Scientific Corp. (US)..............II-49 Deep Brain Innovations, LLC (US) II-50 Medtronic, plc (US).............. II-50 St. Jude Medical, Inc. (US)..............II-51

9. GLOBAL MARKET PERSPECTIVE..............II-53 Table 7: World Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) II-53

Table 8: World Historic Review for Deep Brain Stimulation Devices by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart)..............II-54

Table 9: World 14-Year Perspective for Deep Brain Stimulation Devices by Geographic Region - Percentage Breakdown of Value Sales for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Latin America and Rest of World Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) II-55

III. MARKET

1. THE UNITED STATES.............. III-1 A.Market Analysis.............. III-1 Current & Future Analysis..............III-1 Aging Population and Rising Prevalence of Neurological Disorders: A Strong Market Driver III-1 Table 10: US Population Breakdown by Age Group (2014) (includes corresponding Graph/Chart) III-1

Table 11: Prevalence of Major Neurological Disorders in the US (includes corresponding Graph/Chart) III-2

Table 12: North American Elderly Population in Thousands by Age Group (1975-2050) (includes corresponding Graph/Chart) III-2 Increasing Research Funding to Help DBS III-3 DBS Reimbursement Scenario in the US III-3 Medicare ICD-9-CM Diagnosis Codes for DBS III-3 Medicare ICD 9 CM Diagnosis Procedure Codes for DBS III-4 Medicare HCPCS II Device Codes for DBS III-4 CPT® Procedure Codes and Facility Payment for DBS for the period January to March 2015 III-5 CPT® Procedure Codes and Hospital Outpatient Payment for the period January to December 2015 III-7 CPT® Procedure Codes and Hospital Inpatient Payment for the Period October 2014 to September 2015 III-8 CPT® Procedure Codes and Ambulatory Surgical Center (ASC) Payment for the period January to December 2015 III-9 Strategic Corporate Developments III-10 Select Key Players..............III-12 B.Market Analytics..............III-15 Table 13: US Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-15

Table 14: US Historic Review for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart).............. III-16

2. CANADA.............. III-17 A.Market Analysis.............. III-17 An Overview.............. III-17 B.Market Analytics..............III-17 Table 15: Canadian Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-17

Table 16: Canadian Historic Review for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-18

3. JAPAN.............. III-19 A.Market Analysis.............. III-19 Current & Future Analysis..............III-19 Graying Population Spurs Growth of CNS Therapeutics III-19 Table 17: Japanese Elderly (65+ Years) Population: 2000-2020 (includes corresponding Graph/Chart) III-19 DBS Approvals in Japan..............III-20 List of Approved and Investigational Indications for Deep Brain Stimulation..............III-20 B.Market Analytics..............III-21 Table 18: Japanese Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-21

Table 19: Japanese Historic Review for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-22

4. EUROPE.............. III-23 A.Market Analysis.............. III-23 Current & Future Analysis..............III-23 Ageing Population Boost DBS Devices Demand III-23 Table 20: European Country-wise Statistics of 60+ Population as % of Total Population: 2013 (includes corresponding Graph/Chart)..............III-24 A Brief Note on German DBS Devices Market III-25 Product Approvals/Launches..............III-25 Strategic Corporate Developments III-26 Aleva Neurotherapeutics SA - A Switzerland- based DBS Device Developer.............. III-27 B.Market Analytics..............III-28 Table 21: European Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices by Geographic Region - France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-28

Table 22: European Historic Review for Deep Brain Stimulation Devices by Geographic Region - France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart).............. III-29

Table 23: European 14-Year Perspective for Deep Brain Stimulation Devices by Geographic Region - Percentage Breakdown of Value Sales for France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-30

5. ASIA-PACIFIC.............. III-31 A.Market Analysis.............. III-31 Current & Future Analysis..............III-31 India & China Offer Significant Growth Opportunities III-31 Table 24: China and India Lead Global Population (2014): Table Depicting China and India's Huge Population Vis-à-vis Other Countries' Population (in Thousands) by Age Group (includes corresponding Graph/Chart) III-32 B.Market Analytics..............III-33 Table 25: Asia-Pacific Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices by Geographic Region - China, India and Rest of Asia-Pacific Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-33

Table 26: Asia-Pacific Historic Review for Deep Brain Stimulation Devices by Geographic Region - China, India and Rest of Asia-Pacific Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-34

Table 27: Asia-Pacific 14-Year Perspective for Deep Brain Stimulation Devices by Geographic Region - Percentage Breakdown of Value Sales for China, India and Rest of Asia-Pacific Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-35

5a. CHINA.............. III-36 A.Market Analysis.............. III-36 Current & Future Analysis..............III-36 Market Overview.............. III-36 Breaking the Monopoly of Global Giants III-36 B.Market Analytics..............III-37 Table 28: Chinese Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-37

Table 29: Chinese Historic Review for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart).............. III-38

5b. INDIA.............. III-39 A.Market Analysis.............. III-39 Current & Future Analysis..............III-39 Indian DBS Market on the Roll..............III-39 Growing Medical Tourism to Support DBS Market in India III-39 B.Market Analytics..............III-40 Table 30: Indian Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-40

Table 31: Indian Historic Review for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart).............. III-41

5c. REST OF ASIA-PACIFIC..............III-42 A.Market Analysis.............. III-42 Current & Future Analysis..............III-42 Overview of the Australian DBS Market III-42 Competitive Landscape..............III-42 B.Market Analytics..............III-43 Table 32: Rest of Asia-Pacific Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-43

Table 33: Rest of Asia-Pacific Historic Review for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-44

6. LATIN AMERICA.............. III-45 Market Analysis.............. III-45 Table 34: Latin American Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices by Geographic Region - Brazil and Rest of Latin American Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-45

Table 35: Latin American Historic Review for Deep Brain Stimulation Devices by Geographic Region - Brazil and Rest of Latin American Markets Independently Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-46

Table 36: Latin American 14-Year Perspective for Deep Brain Stimulation Devices by Geographic Region - Percentage Breakdown of Value Sales for Brazil and Rest of Latin American Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-47

7. REST OF WORLD.............. III-48 Market Analysis.............. III-48 Table 37: Rest of World Recent Past, Current & Future Analysis for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2014 through 2020 (includes corresponding Graph/Chart) III-48

Table 38: Rest of World Historic Review for Deep Brain Stimulation Devices Market - Analyzed with Annual Sales Figures in US$ Thousand for Years 2007 through 2013 (includes corresponding Graph/Chart) III-49

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 14 (including Divisions/Subsidiaries - 15)

The United States (8) Canada (1) Europe (5) - France (1) - Germany (2) - Rest of Europe (2) Asia-Pacific (Excluding Japan) (1)
Read the full report: http://www.reportlinker.com/p03180735-summary/view-report.html

About Reportlinker
ReportLinker is an award-winning market research solution. Reportlinker finds and organizes the latest industry data so you get all the market research you need - instantly, in one place.

http://www.reportlinker.com

__________________________
Contact Clare: [email protected]
US: (339)-368-6001
Intl: +1 339-368-6001