Global Commercial Biotechnology Separation Systems Industry

LONDON, Feb. 29, 2016 /PRNewswire/ -- This report analyzes the worldwide markets for Commercial Biotechnology Separation Systems in US$. The Global market is further analyzed by the following Types: DNA Microarray, Flow Cytometry, Liquid Chromatography, Membrane Filtration, Protein Microarray, and Others. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Middle East & Africa, and Latin America. Annual estimates and forecasts are provided for the period 2014 through 2020. Also, a seven-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs. The report profiles 46 companies including many key and niche players such as -

3M Purification, Inc.
AB Sciex
Affymetrix, Inc.
Agilent Technologies, Inc.
Alfa Laval AB



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I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations I-1 Disclaimers.............. I-2 Data Interpretation & Reporting Level I-2 Quantitative Techniques & Analytics I-3 Product Definitions and Scope of Study I-3

II. EXECUTIVE SUMMARY

1. OUTLOOK.............. II-1 Separation Technologies Drive Biotechnology Industry II-1 Developed Markets Lead the Way while Emerging Markets Promise Growth.............. II-1 Liquid Chromatography Leads Biotechnology Separation Technologies II-2

2. INDUSTRY OVERVIEW, TRENDS & DRIVERS II-3 Bioseparation Systems - Invaluable Tools in Biopharmaceutical Manufacturing.............. II-3 A Peek into Biopharmaceutical Manufacturing II-3 Downstream Processing of Biosynthetic Products - An Overview II-4 Growing Biopharmaceuticals Market Drives Demand for Bioseparation Systems..............II-5 2014-15: A Launch-Driven Period for Biopharmaceuticals II-6 Recently Approved Biopharmaceuticals: 2013, 2014 & 2015 II-7 Evolving Biopharmaceutical Industry Emphasizes on Novel Technologies.............. II-8 Increasing Competition Spurs Renewed Focus on Efficiencies II-9 Growing Orphan Drugs Market Draws Attention towards Manufacturing Flexibility..............II-9 Downstream Processing - A Major Trend among Biopharmaceutical Manufacturers.............. II-10 Upstream and Downstream Mismatch Turns Focus towards Innovative Technologies..............II-11 Protein Separation in Biopharmaceutical Space Assumes Greater Significance.............. II-11 Growing Market for Monoclonal Antibodies - Review of Current Status and Future Prospects..............II-12 Approved Monoclonal Antibodies for Therapeutic Use: 1986-2014 II-13 An Insight into Bioseparation of mAbs II-14 Market Potential for Biosimilars - A Case for Substantial Demand for Separation Technologies II-14 Table 1: Global Biosimilars Market in US$ Billion for 2012-2018 (includes corresponding Graph/Chart) II-15 2015: A Year of Patent Expiries for Biologics II-15 Patent Expiries of Major Biopharmaceutical Drugs in the US and Europe.............. II-16 Huge Biopharmaceutical Pipeline - A Clear Indicator of Future Prospects.............. II-17 Table 2: Biopharmaceutical Products Pipeline by Therapeutic Category (2015) (includes corresponding Graph/Chart) II-17

Table 3: Number of Pipeline Biopharmaceuticals for Cancer by Site (2015) (includes corresponding Graph/Chart) II-18

Table 4: Number of Pipeline Biopharmaceuticals for HIV/AIDS Treatment by Type of Therapy (2015) (includes corresponding Graph/Chart).............. II-18 Disposables to Infuse Cost Effectiveness in Biopharmaceutical Production.............. II-19 Single-Use Products Gain Significant Attention II-19 Market Prospects for Single-Use Disposable Technologies II-20 Select Commercial Disposable/Single-Use Technologies by Process Technique..............II-21 Innovations in Single-use Systems II-21 Modular Bioprocessing - An Emerging Trend II-22 Leachables and Extractables Trounce Enthusiasm around Disposables.............. II-22

3. SEPARATION TECHNOLOGIES - MARKET ANALYSIS II-23 Chromatography - the Gold Standard Separation and Purification Technology.............. II-23 Market Outlook.............. II-23 Ongoing Developments and Innovations Create Strong Demand for Columns.............. II-24 Superior Efficiency Drives Use of Synthetic Ligands in Affinity Chromatography..............II-25 Pre-packed Disposable Columns in Chromatography Gain Attention II-25 Clinical Trials - the Largest Market for Pre-packed Disposable Columns..............II-26 GE Leads Pre-packed Disposable Columns Market for Chromatography.............. II-27 Table 5: Leading Players in the Global Pre-packed, Disposable Columns for Chromatography (2014): Percentage Breakdown of Revenues for Atoll Bio, EMD-Millipore, GE Healthcare, Repligen and Others (includes corresponding Graph/Chart).............. II-27 SMBC - An Old Approach Gaining Significant Attention II-28 Major Advantages and Disadvantages of SMBC II-28 Twin-Column SMB - An Emerging Alternative to Protein A Columns II-28 Growing Focus on Alternatives to Protein A Chromatography II-29 Precipitation and Crystallization - Techniques with Major Use in Protein Purification II-30 Reversible Precipitation - A Novel Bioseparation Technology II-30 Alternatives to Protein A-based Chromatography to See Significant Adoption..............II-31 Inherent Benefits of Membrane Chromatography to Drive its Use in Bioprocessing..............II-31 Microarrays Witness Tremendous Growth II-31 Protein Biochips - Set for Robust Expansion II-32 Lab-on-a-Chip: Fusion of Nanotechnology & Genetic Engineering II-32 Current Approaches to Biochips..............II-32 Advancements in Biochip Technology II-33 Technological Differentiation in Demand II-33 Biochip Technology Boosts Personalized Medicine II-34 Biochip Technology Spreads beyond Pharma Industry II-34 Data on Specificity of Effect Drives Use of Microarrays in Cosmetics and Personal Healthcare II-34 Need for Alternative Techniques - The Key Drawback II-36 Membrane Separation - A Promising Separation Technology II-36 Growing Use of Membrane Filtration in Biopharmaceutical Manufacturing.............. II-36 Membrane Adsorbers Gain Ground in Biopharmaceutical Downstream Purification..............II-36 Prospering Vaccine Market Drives Use of Ultrafiltration Techniques.............. II-37 Membrane Filtration Gains Widespread Application in Food Industry.............. II-37 Membrane Separation in Dairy Industry II-38 A Note on Applications of Select Other Membrane Technologies in Dairy Industry II-38 Ultrafiltration - A Widely Used Technique for Mineral Separation from Milk Products II-39 Polymeric Membrane-based Separations Gain Attention in Dairy Sector.............. II-39 Novel Techniques Emerge to Prevent Solubility of Milk Protein Concentrate..............II-39 Flow Cytometry - A Key Laboratory Analytical Technology II-40 Developing Countries Present Growth Opportunities II-41 Cell-based Flow Cytometry Lead the Pack II-42 Research & Clinical Laboratories - Largest End-Use Segments II-42 A Gist of Major Growth Drivers II-42 Growth Barriers/Key Challenges II-43 Technological Advances Boost Cytometric System Sales II-43 Novel Cytometers Advance Technological Evolution II-44 Mass Cytometry - A New Technology in Flow Cytometry II-45 Microfluidics Take Cell Sorting to a New Level II-45 Flow Cytometer Faces Competition from Alternative Instruments II-46 Increasing Role of Flow Cytometry in Disease Diagnosis II-47 IVD Application Market Set to Rise II-47 Large-Scale Screening Operations - Untapped Domain II-47 Rising Use of Image Flow Cytometry in Clinical Applications II-48 Rising HIV Prevalence Provides Growth Opportunities for POC Flow Cytometry.............. II-48 Competitive Scenario in the Global Flow Cytometry Market II-49 Table 6: Leading Players in the Global Flow Cytometers Market (2013): Percentage Breakdown of Value Sales for Becton Dickinson and Company (BD), Danaher/Beckman Coulter, and Others (includes corresponding Graph/Chart) II-50 Centrifugation - A Key Separation Technology in Biopharmaceutical Production..............II-50 Growing Proteomic Research Drives Demand for Electrophoresis Equipment.............. II-51 Major Application Areas of Electrophoresis Equipment II-51 Table 7: Global Capillary Electrophoresis Equipment Market by Application Sector (2013): Percentage Share Breakdown of Value Sales for Pharmaceutical, Bioscience, Chemical, Food/Beverages and Other Application Sectors (includes corresponding Graph/Chart)..............II-52 Capillary Electrophoresis Gains Prominence II-52 2D Gel Electrophoresis Market Gains Ground II-53 Overview of the 2D Gel Electrophoresis Market II-53 Advent of 2D-DIGE.............. II-53 Table 8: World 2D Gel Electrophoresis Market by Segment (2013): Percentage Share Breakdown of Value Sales for Reagents, Instruments/ Apparatus and Informatics (includes corresponding Graph/Chart)..............II-54 Factors Driving Growth of Two-Dimensional Gel Electrophoresis Market..............II-54 Reconfigured by Technology..............II-54 Product Innovations Sustain Sales II-55 Advanced Gel-Imaging Systems: An Emerging Market with Promising Growth..............II-55 High Level of Fragmentation Typifies Electrophoresis Competitive Landscape..............II-55 Magnetic Separations - An Overview II-56

4. PRODUCT OVERVIEW.............. II-57 Biotechnology Separation Systems - An Overview II-57 Flow Cytometry - An Introduction II-57 Flow Cytometers.............. II-58 Fluidics System..............II-58 Optical System.............. II-59 Electronics System..............II-59 Application Areas - An Overview II-59 Versatile Use.............. II-59 Clinical Applications..............II-59 Research Applications..............II-60 Drug Discovery..............II-60 Biomedical Research..............II-60 Fetal Cell Separation..............II-60 Stem Cell Sorting..............II-61 Marine Biology and Environmental Sciences II-61 Microbiology.............. II-61 Chromatography: A Popular Separation Technology II-61 Liquid Chromatography - An Overview II-62 General Scheme.............. II-63 Column Chromatography..............II-63 Chromatography Components..............II-64 Mobile Phase.............. II-64 Stationary Phase..............II-64 Advantages and Disadvantages of Different Types of Liquid Chromatography..............II-64 Membrane Separation..............II-65 Biochips - Complex Blend of Biochemistry and Electronics II-65 Classification of Biochips..............II-66 Microarrays.............. II-67 Centrifuges - A Technical Overview II-67 Batch and Semi-Batch Centrifugation II-68 Types of Preparative Centrifuges II-68 Tubular Bowl Centrifuge..............II-68 Disk Stack Centrifuge..............II-68 Chamber Bowl.............. II-69 Ultracentrifuge..............II-69 Decanter Centrifuge..............II-69 Centrifugal Filter..............II-69 Electrophoresis.............. II-69 Types of Electrophoresis..............II-70 Conventional/Gel Electrophoresis II-70 Slab Gel Electrophoresis..............II-70 Polyacrylamide Gel Electrophoresis (PAGE) II-70 Two-Dimensional Gel Electrophoresis II-70 Capillary Electrophoresis..............II-71 Advantages of Capillary Electrophoresis Instruments II-71 Enables Sizing of a Piece of DNA Down to a Single Base II-71 Exhibits High Resolution and Fluorescently Labels Multiplexed PCR Products II-72 Allow Rapid Separations Due to Generation of High Voltages II-72 Produces Reliable Analysis Results II-72 Allows Residual Disease Testing of Engraftment Studies of Bone Marrow Transplant..............II-72 Allows Testing for FLT3 Mutation II-72 Separation Techniques Employed in CE II-72

5. PRODUCT INNOVATIONS/INTRODUCTIONS II-74 EMD Millipore Launches Sterilizing-Grade Millipore Express® PHF Hydrophilic Filters..............II-74 Novasep Unveils BioSC® Lab..............II-74 EMD Millipore Unveils Pellicon® Tangential Flow Filtration System II-74 ImmunoReagents and ProteoVec Launch PV-Pure Ig™ Antibody Purification Kits..............II-74 BASF Launches PRODIAS Project in Collaboration with Eight Partners.............. II-74 AMSBIO Introduces MagSi-Direct for Bioseparations II-74 EMD Millipore Rolls Out PureFlex™ Plus Disposable Process Container Film.............. II-75 EMD Millipore Rolls Out New Resins for Chromabolt® Chromatography Columns..............II-75 Thermo Fisher Scientific Launches New Chromatography Resin II-75 Thermo Fisher Scientific to Introduce GlycanPac AXR-1 Column at Pittcon 2014.............. II-75 Purolite to Develop Bioseparation Resins for Chromatography II-75 EMD Millipore Unveils Innovative Single-Stage Clarification Clarisolve® Depth Filters..............II-75 Novasep Rolls Out Sius™ Single-Use TFF Skid II-75 Thermo Fisher Scientific Introduces New 3000 BioRS System II-76 Thermo Fisher Scientific Launches SEC-300 and SEC-1000 HPLC Columns.............. II-76 EMD Millipore Introduces Smart Flexware® Assemblies Along with Mobius® FlexReady Solution..............II-76

6. RECENT INDUSTRY ACTIVITY..............II-77 Merck Acquires Sigma-Aldrich..............II-77 Novasep and CPI Install BioSC Lab at UK National Biologics Manufacturing Centre..............II-77 Anteo Diagnostics Inks South Korean Distribution Agreement with KomaBiotech.............. II-77 GE Healthcare and Sartorius Stedim Biotech Ink OEM Supply Agreement for Sartobind™ Technology II-77 Pall Inks Exclusive License for AWS Technology from FDS II-77 Novasep Inks Partnership with Allied Laboratories and AR Brown II-77 Pall Acquires Tarpon's BioSMB Platform II-78 Stora Enso Takes Over Virdia..............II-78 Pall Corporation Acquires ATMI's Life Sciences Business Division II-78 AB Sciex and Beckman Coulter Combine CE and Chromatography Businesses.............. II-78

7. FOCUS ON SELECT PLAYERS..............II-79 3M Purification, Inc. (US)..............II-79 AB Sciex (US).............. II-79 Affymetrix, Inc. (US)..............II-79 Agilent Technologies, Inc. (US)..............II-80 Alfa Laval AB (Sweden)..............II-80 Alfa Wassermann Inc. (US)..............II-81 Atoll GmbH (Germany)..............II-81 Beckman Coulter, Inc. (US)..............II-81 Becton, Dickinson and Company (US) II-82 Bio-Rad Laboratories, Inc. (US)..............II-82 Flottweg SE (Germany)..............II-82 Fluidigm Corporation (US)..............II-83 GE Healthcare (UK)..............II-83 Groupe Novasep (France)..............II-84 Hitachi Koki Co., Ltd. (Japan) II-84 Illumina, Inc. (US).............. II-84 Merck KGaA (Germany)..............II-85 Pall Corporation (US)..............II-85 PerkinElmer, Inc. (US)..............II-86 ProMetic Life Sciences, Inc. (Canada) II-86 Repligen Corporation (US)..............II-87 Sartorius Stedim Biotech SA (France) II-87 SEPMAG Technologies (Spain)..............II-87 Shimadzu Scientific Instruments (US) II-88 Spectrum Laboratories, Inc. (US) II-88 Sysmex Partec GmbH (Germany)..............II-88 Thermo Fisher Scientific, Inc. (US) II-89

8. GLOBAL MARKET PERSPECTIVE..............II-90 Table 9: World Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East & Africa and Latin American Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. II-90

Table 10: World Historic Review for Commercial Biotechnology Separation Systems by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East & Africa and Latin American Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) II-91

Table 11: World 14-Year Perspective for Commercial Biotechnology Separation Systems by Geographic Region - Percentage Breakdown of Revenues for US, Canada, Japan, Europe, Asia-Pacific (excluding Japan), Middle East & Africa and Latin American Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) II-92

Table 12: World Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems by Type - DNA Microarray, Flow Cytometry, Liquid Chromatography, Membrane Filtration, Protein Microarray and Others Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. II-93

Table 13: World Historic Review for Commercial Biotechnology Separation Systems by Type - DNA Microarray, Flow Cytometry, Liquid Chromatography, Membrane Filtration, Protein Microarray and Others Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............II-94

Table 14: World 14-Year Perspective for Commercial Biotechnology Separation Systems by Type - Percentage Breakdown of Revenues for DNA Microarray, Flow Cytometry, Liquid Chromatography, Membrane Filtration, Protein Microarray and Others Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............II-95

III. MARKET

1. THE UNITED STATES.............. III-1 A.Market Analysis.............. III-1 Current & Future Analysis..............III-1 United States: The Largest Biopharmaceutical Market Globally III-1 Table 15: No. of Biologics Approved by the Center for Biologics Evaluation and Research (CBER): 2003-2013 (includes corresponding Graph/Chart) III-1 Impending Patent Expiries Signal Growth Prospects III-2 Table 16: Leading US Biopharmaceuticals by Revenue (in US$ Billion) and Year of Patent Expiry (includes corresponding Graph/Chart).............. III-3 Select Trends in Biopharmaceutical Market III-3 Manufacturers Shift Focus to Small Bioreactors III-3 Biosimilar Drug Developers Face Higher Litigation Risks III-4 US Flow Cytometry Market - An Overview III-4 Table 17: Leading Players in the US Flow Cytometry Market (2014): Percentage Breakdown of Sales for Becton Dickinson, Beckman Coulter, and Others (includes corresponding Graph/Chart).............. III-5 Growth in Protein Electrophoresis Segment to Persist III-5 Factors Influencing Purchasing Decisions in Protein Electrophoresis Equipment Market III-5 Major Factors Influencing Purchasing Decision for Protein Electrophoresis..............III-6 Key Trends in the US PE Market III-6 Ready-Made Gels Grow at the Expense of Hand-Cast Gels III-6 Product Launches..............III-7 Strategic Corporate Developments III-8 Key Players.............. III-9 B.Market Analytics..............III-17 Table 18: US Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-17

Table 19: US Historic Review for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-18

2. CANADA.............. III-19 A.Market Analysis.............. III-19 Current & Future Analysis..............III-19 Canada - A Lucrative Biopharmaceutical Industry III-19 Key Player.............. III-19 B.Market Analytics..............III-20 Table 20: Canadian Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-20

Table 21: Canadian Historic Review for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-21

3. JAPAN.............. III-22 A.Market Analysis.............. III-22 Current & Future Analysis..............III-22 Strategic Corporate Development III-22 Key Player.............. III-22 B.Market Analytics..............III-23 Table 22: Japanese Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-23

Table 23: Japanese Historic Review for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-24

4. EUROPE.............. III-25 A.Market Analysis.............. III-25 Current & Future Analysis..............III-25 European Biopharmaceutical Industry - Select Trends III-25 Funding Challenges Faced by Biopharmaceutical Startups III-25 Healthcare Agencies Looking to Embrace Biosimilars to Cut Healthcare Costs..............III-25 B.Market Analytics..............III-27 Table 24: European Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems by Geographic Region - France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-27

Table 25: European Historic Review for Commercial Biotechnology Separation Systems by Geographic Region - France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-28

Table 26: European 14-Year Perspective for Commercial Biotechnology Separation Systems by Geographic Region - Percentage Breakdown of Revenues for France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-29

4a. FRANCE.............. III-30 A.Market Analysis.............. III-30 Current & Future Analysis..............III-30 Product Launches..............III-30 Key Players.............. III-30 B.Market Analytics..............III-31 Table 27: French Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-31

Table 28: French Historic Review for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-32

4b. GERMANY.............. III-33 A.Market Analysis.............. III-33 Current & Future Analysis..............III-33 Strategic Corporate Development III-33 Key Players.............. III-33 B.Market Analytics..............III-35 Table 29: German Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-35

Table 30: German Historic Review for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-36

4c. ITALY.............. III-37 Market Analysis.............. III-37 Table 31: Italian Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-37

Table 32: Italian Historic Review for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-38

4d. THE UNITED KINGDOM..............III-39 A.Market Analysis.............. III-39 Current & Future Analysis..............III-39 Product Launch.............. III-39 Strategic Corporate Developments III-39 Key Player.............. III-40 B.Market Analytics..............III-41 Table 33: UK Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-41

Table 34: UK Historic Review for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-42

4e. SPAIN.............. III-43 A.Market Analysis.............. III-43 Current & Future Analysis..............III-43 Key Player.............. III-43 B.Market Analytics..............III-44 Table 35: Spanish Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-44

Table 36: Spanish Historic Review for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-45

4f. RUSSIA.............. III-46 A.Market Analysis.............. III-46 Current & Future Analysis..............III-46 Russia Sets Eyes on Emerging as a Notable Pharmaceutical Industry.............. III-46 Encouragement for Local Manufacturing to Drive Demand III-46 Challenges - Need for Extensive R&D III-47 B.Market Analytics..............III-48 Table 37: Russian Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-48

Table 38: Russian Historic Review for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-49

4g. REST OF EUROPE.............. III-50 A.Market Analysis.............. III-50 Current & Future Analysis..............III-50 Key Player.............. III-50 B.Market Analytics..............III-51 Table 39: Rest of Europe Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-51

Table 40: Rest of Europe Historic Review for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-52

5. ASIA-PACIFIC.............. III-53 A.Market Analysis.............. III-53 Current & Future Analysis..............III-53 Asia Set to Emerge as Preferred Outsourcing Destination for Biopharma Manufacturing..............III-53 B.Market Analytics..............III-54 Table 41: Asia-Pacific Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems by Geographic Region - China, India and Rest of Asia-Pacific Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-54

Table 42: Asia-Pacific Historic Review for Commercial Biotechnology Separation Systems by Geographic Region - China, India and Rest of Asia-Pacific Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-55

Table 43: Asia-Pacific 14-Year Perspective for Commercial Biotechnology Separation Systems by Geographic Region - Percentage Breakdown of Revenues for China, India and Rest of Asia-Pacific Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-56

5a. CHINA.............. III-57 Market Analysis.............. III-57 Table 44: Chinese Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-57

Table 45: Chinese Historic Review for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-58

5b. INDIA.............. III-59 A.Market Analysis.............. III-59 Current & Future Analysis..............III-59 Favorable End-use Market Dynamics Drive Demand for Flow Cytometers.............. III-59 Table 46: Flow Cytometry Market in India (2014): Percentage Breakdown of Sales by End-Use Industry - Life Sciences, Clinical Research and Pharmaceutical (includes corresponding Graph/Chart)..............III-59

Table 47: Indian Market for Flow Cytometers by Product (2013): Percentage Share Breakdown of Value Sales for Instruments and Reagents (includes corresponding Graph/Chart).............. III-60

Table 48: Indian Market for Flow Cytometers Reagents (2013): Percentage Share Breakdown of Value Sales by Application (includes corresponding Graph/Chart) III-60 Factors Affecting the Market..............III-60 Competitive Landscape in the Indian Flow Cytometry Market III-61 Indian Electrophoresis Market - An Overview III-61 Key Growth Drivers of The Electrophoresis Market III-62 Drug Production Requirements Boost Growth III-62 Competitive Landscape..............III-62 B.Market Analytics..............III-63 Table 49: Indian Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-63

Table 50: Indian Historic Review for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-64

5c. REST OF ASIA-PACIFIC..............III-65 A.Market Analysis.............. III-65 Current & Future Analysis..............III-65 Strategic Corporate Development III-65 B.Market Analytics..............III-65 Table 51: Rest of Asia-Pacific Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-65

Table 52: Rest of Asia-Pacific Historic Review for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-66

6. MIDDLE EAST & AFRICA.............. III-67 Market Analysis.............. III-67 Table 53: Middle East & African Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-67

Table 54: Middle East & African Historic Review for Commercial Biotechnology Separation Systems Market Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-68

7. LATIN AMERICA.............. III-69 Market Analysis.............. III-69 Table 55: Latin American Recent Past, Current & Future Analysis for Commercial Biotechnology Separation Systems by Geographic Region - Brazil and Rest of Latin American Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-69

Table 56: Latin American Historic Review for Commercial Biotechnology Separation Systems by Geographic Region - Brazil and Rest of Latin American Markets Independently Analyzed with Annual Revenue Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-70

Table 57: Latin American 14-Year Perspective for Commercial Biotechnology Separation Systems by Geographic Region - Percentage Breakdown of Revenues for Brazil and Rest of Latin American Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-71

IV. COMPETITIVE LANDSCAPE

Total Companies Profiled: 46 (including Divisions/Subsidiaries - 51)

The United States (27) Canada (1) Japan (4) Europe (16) - France (2) - Germany (8) - The United Kingdom (1) - Spain (2) - Rest of Europe (3) Asia-Pacific (Excluding Japan) (3)
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