Global Blood Banking and Blood Products Industry

LONDON, Dec. 9, 2015 /PRNewswire/ -- This report analyzes the worldwide markets for Blood Banking and Blood Products in US$ Million by the following Product Group/Types: Blood Components and Plasma Products (Whole Blood & Cellular Components; and Plasma Fractions), and Equipment, Blood Tests and Other Consumables. The report provides separate comprehensive analytics for the US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World. Annual estimates and forecasts are provided for the period 2014 through 2020. Also, a seven-year historic analysis is provided for these markets. Market data and analytics are derived from primary and secondary research. Company profiles are primarily based on public domain information including company URLs. The report profiles 235 companies including many key and niche players such as -

AABB
Americas Blood Centers
American Red Cross
Canadian Blood Services
Japan Red Cross Society



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I. INTRODUCTION, METHODOLOGY & PRODUCT DEFINITIONS

Study Reliability and Reporting Limitations I-1 Disclaimers.............. I-2 Data Interpretation & Reporting Level I-2 Quantitative Techniques & Analytics I-3 Product Definitions and Scope of Study I-3 Blood Components and Plasma Products I-3 Whole Blood & Cellular Components I-3 WBCs.............. I-4 RBCs.............. I-4 Platelets.............. I-4 Plasma Fractions..............I-4 Fresh Frozen Plasma..............I-4 Albumin Fractions..............I-4 Factor VIII.............. I-4 Factor IX and Factor IX Complex I-5 Fibrin/Thrombin..............I-5 Equipment, Blood Tests and Consumables I-5 Automated Analyzers for Blood Analysis I-5 Blood Test Consumables..............I-5

II. EXECUTIVE SUMMARY

1. MARKET OVERVIEW.............. II-1 Prelude.............. II-1 Blood Transfusion Worldwide: A Kaleidoscope of Stark Contrasts II-1 Safety and Availability: The Core Issues II-2 Table 1: Prevalence of Major Transfusion-transmitted Infections by Economic Group (H2 2014): Percentage of HIV, HBV and HCV in High Income, Middle-income and Low Income Countries (includes corresponding Graph/Chart) II-3 Current and Future Analysis..............II-4 Analysis of World Blood Banking & Blood Products by Value Sales II-4 Analysis by Geographic Region..............II-4 Analysis by Product Group/Type II-4 Plasma and Plasma Derivatives Continue to Dominate Blood Components Market..............II-4 Table 2: Global Plasma Derivatives Market by Product (2015E & 2017P): Percentage Breakdown of Consumption Value for Albumin, Alpha-1, FVIII, IVIg, and Others (includes corresponding Graph/Chart) II-5 Equipment, Blood Tests & Other Consumables to Display Steady Growth.............. II-6 World Blood Components and Plasma Market Analysis II-7 Table 3: World Recent Past, Current & Future Analysis for Blood Components and Plasma by Region/Country - US, Europe, Japan, and Rest of World Markets Independently Analyzed with Annual Consumption in Million Units for Years 2014 through 2020 (includes corresponding Graph/Chart) II-8

Table 4: World 7-Year Perspective for Blood Components and Plasma by Region/ Country - Percentage Breakdown of Volume Consumption for US, Europe, Japan, and Rest of World Markets for Years 2014, 2015 & 2020 (includes corresponding Graph/Chart).............. II-9 Red Blood Cells - A Key Blood Component II-10 Table 5: World Recent Past, Current & Future Analysis for Red Blood Cells by Region/ Country - US, Europe, Japan, and Rest of World Markets Independently Analyzed with Annual Consumption in Million Units for Years 2014 through 2020 (includes corresponding Graph/Chart) II-10

Table 6: World 7-Year Perspective for Red Blood Cells by Region/Country - Percentage Breakdown of Volume Consumption for US, Europe, Japan, and Rest of World Markets for Years 2014, 2015 & 2020 (includes corresponding Graph/Chart) II-11

2. MARKET TRENDS & ISSUES..............II-12 Blood Plasma Demand Exceeds Supply: Self-Sufficiency is the New Mantra.............. II-12 Manufacturers Step Up Production Capacity to Meet Growing Demand for Plasma Derivative Products II-12 Platelet Rich Plasma Therapy Market Scales New Heights II-12 Increasing Awareness of PID and CIPD Disorders to Drive IVIg Market.............. II-13 Indications Addressed by Major Global IVIg Manufacturers II-14 Table 7: Comparative Costs between Plasma Protein Therapies and Artificially Synthesized Pharmaceuticals (includes corresponding Graph/Chart)..............II-14 Growing Affinity for Home Care Unlocks Opportunities for Home-based IVIg Therapy..............II-15 Table 8: Worldwide Home Healthcare Services Market by Type of Service (2015E & 2020P): Percentage Breakdown of Service Revenues for Infusion Therapy Services, Rehabilitation Services, Respiratory Therapy Services, Telemetry, and Unskilled Homecare (includes corresponding Graph/Chart) II-17 Unsuccessful Clinical Trials for Alzheimer's a major Setback for IVIg Market.............. II-17 Huge Under-Diagnosed Pool of AAT Patients Highlights High Potential for Alpha-1 Protein..............II-18 Rising Incidence of Cancer Drives Demand for Apheresis Systems II-18 PrIME: An Innovative High-Yield Process to Address Supply Dearth II-19 Present State of Plasma Fractionating Industry II-19 Plasma Fractionation Industry Concentrated in Developed Countries.............. II-20 PrIME Tackles the Issue of Currently Unprocessable Plasma II-20 Industry Grappling with Blood Safety & Availability Issues II-20 New Infections - A Continuous Threat II-21 Synthetic Substitutes to Bridge Demand-Supply Gap in Blood II-21 Autologous Transfusion Gearing up for High Growth II-22 Out-of-Hospital Transfusions: An Emerging Phenomenon II-22 Automation Tapping into Blood Market II-23 Automated in Pre-Transfusion Diagnostics II-23 Penetration of Automated Equipment in the Plasma Market II-23 The Red Blood Cell Collection Opportunity II-23 Robots in Blood Banking..............II-24 Blood Banks Switching from Manual to Automated Cooler Validation.............. II-24 Automated Blood Processing Systems in Open Heart Surgeries II-24 Automated Systems in Cancer..............II-25 Pooling: Economical HIV Testing..............II-25 Ballooning Global Geriatric Populace to Drive Demand for Blood Products`.............. II-25 Table 9: Elderly Population (65+ Years) as a Percentage of the Total Population: 2014 & 2025 (includes corresponding Graph/Chart).............. II-26

Table 10: Life Expectancy at Age 60 and 80 Years - (2010-2015), (2020-2025) & (2045-2050) (includes corresponding Graph/Chart)..............II-26 Improving Healthcare Expenditure to Foster Growth of Blood Banking Sector.............. II-27 Table 11: Global Intravenous Immunoglobulin Consumption in Kilograms per Million Residents for Select Countries (includes corresponding Graph/Chart) II-28

Table 12: Per-Capita Healthcare Expenditure in US$ for Select Regions (2014) (includes corresponding Graph/Chart) II-29

3. COMPETITIVE LANDSCAPE..............II-30 Leaders in Global Blood Plasma Ramp Up Market Share II-30 Table 13: Global Plasma Fractionation Capacity by Leading Producers (2016 & 2020): Percentage Breakdown of Production Capacity for Baxter, Biotest, CSL, Grifols, Kedrion, Octapharma, and Others (includes corresponding Graph/Chart) II-30 IVIg - A Highly Consolidated Market II-31 Table 14: Global Market for Immunoglobulin (IVIg and SCIg) by Leading Players (2014): Percentage Breakdown of Value Sales for Baxter, CSL, Grifols, Kedrion, Octapharma, and Others (includes corresponding Graph/Chart) II-31

Table 15: Global IVIg Market by Leading Players (2014): Percentage Breakdown of Value Sales for Baxter, CSL, Grifols, Kedrion, Octapharma, and Others (includes corresponding Graph/Chart)..............II-32 Select IVIg Products Offered by Global Leading Players II-32 Table 16: Global Subcutaneous Immunoglobulin Market by Leading Player (2014): Percentage Market Share Breakdown of Revenue for Baxter, CSL, and Grifols (includes corresponding Graph/Chart).............. II-32 Big Three Corner Majority of Blood Collection Systems Market II-33 Table 17: Global Whole Blood Collection Systems Market (2015E): Percentage Breakdown of Value Sales for Fresenius/Fenwal, Haemonetics, MacoPharma, Terumo, WEGO, and Others (includes corresponding Graph/Chart) II-33

Table 18: Global Apheresis Systems Market (2015E): Percentage Breakdown of Value Sales for Fresenius/Fenwal, Haemonetics, Terumo, and Others (includes corresponding Graph/Chart) II-34 Key Statistics.............. II-34 Table 19: Global Human Albumin Market by Leading Players (2014): Percentage Breakdown of Value Sales for Baxter, CSL, Grifols, Octapharma, and Others (includes corresponding Graph/Chart).............. II-34

Table 20: Global Plasma-Derived Factor VIII Market by Leading Players (2014): Percentage Breakdown of Value Sales for Baxter, Biotest, CSL, Grifols, Kedrion, Octapharma, and Others (includes corresponding Graph/Chart) II-34

Table 21: Global Alpha-1 Market by Leading Players (2014): Percentage Breakdown of Value Sales for Baxter, CSL, Grifols, and Others (includes corresponding Graph/Chart) II-35

Table 22: Global In-Vitro Diagnostics Instruments, Reagents & Supplies Market by Leading Players (2015E): Percentage Breakdown of Value Sales for Abbott, bioMérieux, Danaher, Johnson & Johnson, Roche, Siemens, and Others (includes corresponding Graph/Chart)..............II-35

Table 23: Global Molecular Diagnostics Instruments, Reagents & Supplies Market by Leading Players (2015E): Percentage Breakdown of Value Sales for Abbott, Becton Dickinson, Gen-Probe/Hologic, Novartis, Qiagen, Roche, and Others (includes corresponding Graph/Chart) II-35

4. PRODUCT OVERVIEW.............. II-36 Blood Banking and Blood Products Industry II-36 Blood Components and Plasma Products II-36 Equipment, Blood Tests and Consumables II-36 Automated Analyzers for Blood Analysis II-36 Blood Tests.............. II-36 Consumables.............. II-37 Blood Collection Equipment..............II-37 Blood Collection Monitors..............II-37 Blood Donor Couches..............II-37 Blood Processing Equipment..............II-37 Blood Bank Centrifuges..............II-37 Plasma Thawing..............II-37 Blood Cell Separators..............II-38 Blood Storage Equipment..............II-38 Blood Bags.............. II-38 Platelet Agitators..............II-38 Blood Bank Refrigerators..............II-38 Blood - A Primer.............. II-38 Ionic Structure.............. II-38 Blood Components and their Applications II-39 Blood Constituents..............II-40 Plasma.............. II-40 Red Blood Cells (RBC)..............II-40 Blood Count.............. II-41 Platelets.............. II-41 White Blood Cells (WBC)..............II-41 Derivative Products of Blood or Plasma Fractions II-42 Albumin Fractions..............II-42 Immunoglobulins.............. II-42 Hyper-Immune Immunoglobulin..............II-42 Factor VIII.............. II-43 Factor IX and Factor IX Complex II-43 Fibrin/Thrombin.............. II-43 Consumption of Blood Based on Type of Surgery/Accident (In Units).............. II-43 Table 24: Worldwide Market for Plasma Derivative Products by Product Type (2014): Percentage Breakdown of Revenue Sales for A1PI, Albumin, Coagulation Factor, Hyperimmunes, IVIG, Plasma Derived Factor VIII, Prothrombin Complex Concentrate, and Others (includes corresponding Graph/Chart) II-44 Recombinant Products..............II-44 Development Pipeline of Select rFVIII Products Developed for Hemophilia Therapy..............II-45 Blood Plasma Sourcing..............II-45 Table 25: Global Plasma Derivatives Market: Percentage Breakdown of Costs Associated with Production (includes corresponding Graph/Chart)..............II-45 Plasma Protein and Fractionation II-46 Plasma Fractionation: Origins and Development II-46 Table 26: Plasma Fractionation Processes: Comparison of Cohn IVIG and PrIME IVIG Based on Specific Characteristics II-47 The Need.............. II-47 Fresh Frozen Plasma..............II-47 Other Plasma Fractions..............II-48 IVIG.............. II-48 Factor VIII.............. II-48 Albumin.............. II-48 Therapeutic Uses of Plasma Products II-48 Albumin Products.............. II-48 Immunoglobulins.............. II-49 Intravenous Immunoglobulin (IVIg) II-49 Normal Immunoglobulin (IMIg) II-49 CMV Immunoglobulin..............II-49 Hepatitis B Immunoglobulin..............II-49 Rh (D) Immunoglobulin..............II-49 Tetanus Immunoglobulin IM..............II-49 Zoster Immunoglobulin..............II-50 Plasma Derived Coagulant Products II-50 Biostate®.............. II-50 Ceprotin®.............. II-50 Factor VII Concentrate..............II-50 Factor XI Concentrates..............II-50 Feiba VH® Inhibitor Treatment..............II-50 Fibrogammin P®.............. II-50 Monofix®-VF.............. II-50 ProthrombinexTM-HT..............II-51 Thrombotrol®-VF.............. II-51

5. BLOOD COLLECTION METHODS..............II-52 Banking the Natural Blood Resources II-52 Blood Banks.............. II-52 Blood Banking.............. II-52 Blood Transfusion..............II-52 Role of Blood Banks..............II-52 Blood Donor: The Epicenter of the Process II-52 Eligibility Criteria for the Donor II-53 The Basics of Blood Donation - Myths & Facts II-53 Table 27: Active Donors of Whole Blood and Apheresis per 1,000 of Population by Country/ Agency (includes corresponding Graph/Chart)..............II-54

Table 28: Percentage Breakdown of Apheresis and Whole Blood Donations by Country (includes corresponding Graph/Chart) II-55 Collection Methods..............II-55 Blood Donation: The Process..............II-55 Types of Blood Donation..............II-55 Directed Blood Donations..............II-55 Autologous Blood Donation..............II-56 Alternative Usage of Patient's Own Blood II-56 General Blood Donation..............II-56 Hemodilution.............. II-56 Wound Drainage.............. II-56 Cell Saver.............. II-56 The Method.............. II-57 Blood Salvaging.............. II-57 Blood Collection Centers..............II-57 Blood Collection Management System II-57 A Historical Retrospective..............II-57 Blood Collection Centers..............II-57 Types of Blood Collection Centers II-58 Cord Blood Banks.............. II-58 Profit Collection Centers..............II-58 Military Blood Banks..............II-58 Hospital Blood Banks..............II-58 Community Blood Banks..............II-59 Non-Profit Collection Centers II-59 Blood Processing.............. II-59 Blood Typing.............. II-60 Rh Blood Group System..............II-60 ABO Blood Group System..............II-60 Blood Types and their Compatibility II-61 Table 29: Occurrence of Blood Groups Worldwide (In %) (includes corresponding Graph/Chart) II-61 Blood Test.............. II-61 Blood Culture.............. II-62 The Costs.............. II-62 History of Blood Banking..............II-62

6. THE DYNAMIC LANDSCAPE OF TRANSFUSION TECHNOLOGIES & TESTS II-65 Blood Transfusion: A Backdrop..............II-65 Massive Transfusion.............. II-65 Complications and Risks Due to Transfusion II-65 Circulatory Overload..............II-66 Graft Versus Host Disease (GVHD) II-66 Hemolytic Transfusion Reactions II-66 Iron Overload.............. II-66 Bacterial Contamination..............II-66 Thrombophlebitis.............. II-66 Allergic Reactions.............. II-66 Air Embolism.............. II-67 Hyperkalaemia.............. II-67 Changing Role of Blood Banking Technology II-67

7. BLOOD TRANSFUSION: THE PROCESS, TESTS/TECHNOLOGIES II-68 Cross Matching.............. II-68 Blood Donor/Recipient Screening..............II-68 Blood Typing.............. II-68 Leukoreduction.............. II-68 Leukocyte Reduction Specification Standards/Filters II-69 Coombs Test.............. II-69

8. ALTERNATIVES TO BLOOD TRANSFUSION: A REAL THREAT TO THE INDUSTRY II-70 Bloodless Surgery.............. II-70 Therapeutic Apheresis..............II-70 Plasmapheresis.............. II-70 Plateletpheresis.............. II-70 Leukapheresis.............. II-71 Volume Expanders.............. II-71 Colloids.............. II-71 Albumin.............. II-71 Dextrans.............. II-71 Hydroxyethyl Starch..............II-71 Crystalloids.............. II-72 Blood Growth Factor Therapies - Newer Alternatives to Transfusion II-72

9. RECENT INDUSTRY ACTIVITY..............II-73 OneBlood to Merge with The Blood Alliance II-73 Cerus Corporation Inks Purchase Agreement with Karolinska University Hospital..............II-73 Cerus Corporation Signs Purchase Agreement with Blood Bank of Delmarva.............. II-73 Canadian Blood Services Closes 3 Permanent Clinics, Terminates Bloodmobile Program..............II-73 Roche Releases Elecsys HTLV-I/II Immunoassay II-73 Roche Receives USFDA Approval for cobas TaqScreen MPX Test v2 .0 for HIV, HCV, and HBV Tests..............II-73 China Biologic Products Purchases Additional Stake in Guizhou Taibang Biological Products..............II-73 Community Blood Center Merges with New York Blood Center II-74 Cerus Corp. Partners with Kawasumi Laboratories for Developing Intercept Platelets Kits..............II-74 Vascular Solutions Collaborates with US AMMDA to Develop Plasma Products for Treating Hemorrhage II-74 The San Diego Blood Bank Collaborates with Clinical and Translational Research Institute II-74 Affinity Biologicals Unveils Factor VIII Deficient, Factor IX Deficient Plasmas..............II-74 AABB Collaborates with AATM for Promoting Blood and Cellular Therapies Standards in Asia..............II-74 bioCSL Partners with Immucor for Distributing Transfusion Technology in Australia and New Zealand II-75 PrIME Biologics Opens Plasma Fractionation Plant in Singapore II-75 Terumo BCT Acquires Medservice II-75 Grifols Acquires Transfusion Diagnostics Unit of Novartis II-75 Lab21 Divests Blood Bank Screening, Molecular Assets to Trinity Biotech.............. II-75 New York Blood Center Acquires Coral Blood Services II-75 Entegrion Inks Licensing Agreement with Kedrion Melville for Developing Resusix.............. II-75 Davao del Norte Opens New Blood Banking Facility II-75

10. FOCUS ON SELECT GLOBAL PLAYERS II-76 Leading Blood Banks.............. II-76 AABB (USA).............. II-76 America's Blood Centers (USA) II-76 American Red Cross (USA)..............II-77 Canadian Blood Services (Canada) II-77 Japan Red Cross Society (Japan) II-78 New York Blood Center (USA)..............II-78 Sanquin Blood Supply Foundation (The Netherlands) II-78 Leading Players in Blood Bank Technology and Supplies II-79 Abbott Diagnostics, Inc. (USA)..............II-79 Beckman Coulter, Inc. (USA)..............II-79 Becton, Dickinson and Company (USA) II-80 bioMérieux SA (France)..............II-81 Bio-Rad Laboratories, Inc. (USA) II-81 Cerus Corporation (USA)..............II-82 CSL Behring LLC (USA)..............II-82 Fresenius Kabi AG (Germany)..............II-83 Fenwal Inc. (USA).............. II-83 Gen-Probe, Inc. (USA)..............II-84 Haemonetics Corporation (USA) II-84 Immucor Inc. (USA).............. II-85 Kawasumi Laboratories, Inc. (Japan) II-86 MacoPharma SA (France)..............II-86 Ortho-Clinical Diagnostics, Inc. (USA) II-86 Terumo BCT Inc. (USA)..............II-87 Leading Players in Plasma Fractionation II-87 Baxter International Inc. (USA) II-87 Beijing Tiantan Biological Products Co., Ltd (China) II-88 Bharat Serums and Vaccines Ltd (India) II-88 Bio Products Laboratory Ltd (UK) II-88 Biotest AG (Germany)..............II-89 China Biologic Products, Inc. (China) II-89 Grifols S.A. (Spain)..............II-89 Huanlan Biological Engineering Inc. (China) II-91 Kedrion S.p.A. (Italy)..............II-91 LFB Group (France).............. II-91 Octapharma AG (Switzerland)..............II-92 OMRIX Biopharmaceuticals Ltd (Israel) II-92 Shanghai RAAS Blood Products Co., Ltd. (China) II-93 Sichuan Yuanda Shuyang Pharmaceutical Co., Ltd. (China) II-93

11. GLOBAL MARKET PERSPECTIVE..............II-94 Table 30: World Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............II-94

Table 31: World Historic Review for Blood Banking and Blood Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart).............. II-95

Table 32: World 14-Year Perspective for Blood Banking and Blood Products by Geographic Region - Percentage Breakdown of Value Sales for US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) II-96 Blood Banking and Blood Products Market by Product Group/Type II-97 Table 33: World Recent Past, Current & Future Analysis for Blood Components and Plasma Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) II-97

Table 34: World Historic Review for Blood Components and Plasma Products by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............II-98

Table 35: World 14-Year Perspective for Blood Components and Plasma Products by Geographic Region - Percentage Breakdown of Value Sales for US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) II-99

Table 36: World Recent Past, Current & Future Analysis for Blood Components and Plasma Products by Product Type - Whole Blood & Cellular Components, and Plasma Fractions Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. II-100

Table 37: World Historic Review for Blood Components and Plasma Products by Product Type - Whole Blood & Cellular Components, and Plasma Fractions Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) II-101

Table 38: World 14-Year Perspective for Blood Components and Plasma Products by Product Type - Percentage Breakdown of Value Sales for Whole Blood & Cellular Components, and Plasma Fractions Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............II-102

Table 39: World Recent Past, Current & Future Analysis for Whole Blood & Cellular Components by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............II-103

Table 40: World Historic Review for Whole Blood & Cellular Components by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World Markets Independently Analyzed with Annual Sales in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) II-104

Table 41: World 14-Year Perspective for Whole Blood & Cellular Components by Geographic Region - Percentage Breakdown of Value Sales for US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) II-105

Table 42: World Recent Past, Current & Future Analysis for Plasma Fractions by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............II-106

Table 43: World Historic Review for Plasma Fractions by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) II-107

Table 44: World 14-Year Perspective for Plasma Fractions by Geographic Region - Percentage Breakdown of Value Sales for US, Canada, Japan, Europe, Asia-Pacific, Latin America, and Rest of World Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............II-108

Table 45: World Recent Past, Current & Future Analysis for Equipment, Blood Tests and Other Consumables by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) II-109

Table 46: World Historic Review for Equipment, Blood Tests and Other Consumables by Geographic Region - US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............II-110

Table 47: World 14-Year Perspective for Equipment, Blood Tests and Other Consumables by Geographic Region - Percentage Breakdown of Value Sales for US, Canada, Japan, Europe, Asia-Pacific, Latin America and Rest of World Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) II-111

III. MARKET

1. THE UNITED STATES.............. III-1 A.Market Analysis.............. III-1 Current and Future Analysis..............III-1 Demand for Blood Transfusion Continues to Wane III-1 Table 48: US Blood and Organ Banks by Leading Players (2014): Percentage Share Breakdown of Revenues for American Red Cross, Baxter International Inc., Blood Systems, Musculoskeletal Transplant Foundation, New York Blood Center, and Others (includes corresponding Graph/Chart) III-2

Table 49: US Blood Banking Market by Leading Suppliers (2015): Percentage Breakdown of Unit Volumes for American Red Cross, Blood Centers of America, and Others (includes corresponding Graph/Chart)..............III-3

Table 50: American Red Cross Dominates US Blood Platelet Production (2014): Percentage Share Breakdown of Production Volume for American Red Cross, and Others (includes corresponding Graph/Chart)..............III-3 Aging Baby-Boomer Demography: A Key Market Driver III-3 Table 51: North American Elderly Population by Age Group: 1975-2050 (includes corresponding Graph/Chart) III-4 Favorable Reimbursement and High Usage Make US the Largest Consumer of Immunoglobulins Worldwide III-4 Recession Impacts Blood Bank Reserves III-4 US Blood Collection & Supply Profile III-5 Blood Group Distribution..............III-5 Table 52: US Market for Blood Banking and Blood Products: Percentage Breakup of Blood Group by Rh Factor (includes corresponding Graph/Chart) III-6

Table 53: Percentage Breakup of Rh Blood Types in the US by Racial Group (includes corresponding Graph/Chart) III-6 US Plasma Industry Remains Highly Concentrated III-6 Table 54: US Plasma Derivatives Market by Leading Suppliers (2015): Percentage Breakdown of Value Sales for Baxter, CSL, Grifols, and Others (includes corresponding Graph/Chart).............. III-7

Table 55: US Immunoglobulin Market by Leading Players (2014): Percentage Breakdown of Volume Sales for Baxter Healthcare, CSL Ltd., Grifols, and Others (includes corresponding Graph/Chart)..............III-7

Table 56: US Market for Intravenous Immunoglobulin by Leading Player (2014): Percentage Market Share Breakdown of Volume Sales for Baxter, CSL Behring, Grifols, Kedrion, Octapharma, and Others (includes corresponding Graph/Chart) III-8

Table 57: US Market for Immunoglobulin by Leading Players (2014): Percentage Breakdown of Value Sales for Gammagard Liquid/Kiovig, Flebogamma/Gamunex, Privigen/Carimune NF, Octagam and Others (includes corresponding Graph/Chart) III-8

Table 58: US Market for IVIg Products by Indication (2014 & 2020P): Percentage Breakdown of Volume Sales for CIDP, CLL, ITP, MMN, PID, and Other Neurological Diseases (includes corresponding Graph/Chart)..............III-9

Table 59: US Specific Immunoglobulin Market by Product Type (2014): Percentage Breakdown of Value Sales for Anti-D, Anti-HB, Anti-T, and Rabies Immunoglobulin (includes corresponding Graph/Chart)..............III-9

Table 60: US Specific Immunoglobulin Market by Leading Players (2014): Percentage Breakdown of Value Sales for Biotest, Cangene, CSL, Grifols, Kedrion, Sanofi (includes corresponding Graph/Chart)..............III-10 Changing Supply Dynamics Alters Economics of Plasma Production III-10 Table 61: Average Price per Gram of IVIg for Europe and US Markets (includes corresponding Graph/Chart) III-11 Regulations Control Plasma Collection Industry III-12 Key Statistics.............. III-12 Table 62: US Blood Bag (With Filters) Market (2014): Percentage Share Breakdown of Value Sales for Leading Companies - Fresenius/Fenwal, Haemonetics, Terumo, and Others (includes corresponding Graph/Chart) III-12

Table 63: US Whole Blood Collection Market (2014): Percentage Share Breakdown of Volume Sales for Leading Companies - Fresenius/Fenwal, Haemonetics, Terumo and Others (includes corresponding Graph/Chart) III-12

Table 64: US Automated Blood Collection Market (2014): Percentage Share Breakdown of Volume Sales for Leading Companies - Fresenius/ Fenwal, Haemonetics, and Terumo (includes corresponding Graph/Chart) III-13 Strategic Corporate Activity III-13 Select Key Players..............III-14 B.Market Analytics..............III-23 US Blood Components and Plasma Market Analyzed by Value Sales III-23 Table 65: US Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-23

Table 66: US Historic Review for Blood Banking and Blood Products by Product Group/ Segment - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-24

Table 67: US 14-Year Perspective for Blood Banking and Blood Products by Product Group/ Type - Percentage Breakdown of Value Sales for Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-25 US Blood Components and Plasma Market Analyzed by Consumption in Units..............III-26 Table 68: US Recent Past, Current & Future Analysis for Blood Components and Plasma by Blood Components- Red Blood Cells (RBCs), Platelets, and Fresh Frozen Plasma Markets Independently Analyzed with Annual Consumption in Thousand Units for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-26

Table 69: US Historic Review for Blood Components and Plasma by Blood Components - Red Blood Cells (RBCs), Platelets, and Fresh Frozen Plasma Markets Independently Analyzed with Annual Consumption in Thousand Units for Years 2007 through 2013 (includes corresponding Graph/Chart).............. III-27

Table 70: US 14-Year Perspective for Blood Components and Plasma by Blood Components - Percentage Breakdown of Volume Consumption for Red Blood Cells (RBCs), Platelets, and Fresh Frozen Plasma for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-28

2. CANADA.............. III-29 A.Market Analysis.............. III-29 Current and Future Analysis..............III-29 Bleeding Disorders - A Major Threat III-29 'CSA-Z902-04' - A Comprehensive Voluntary Blood Safety Standard III-29 Strategic Corporate Developments III-30 Canadian Blood Services - The Major Blood Bank III-30 B.Market Analytics..............III-31 Table 71: Canadian Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-31

Table 72: Canadian Historic Review for Blood Banking and Blood Products by Product Group/ Segment - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-32

Table 73: Canadian 14-Year Perspective for Blood Banking and Blood Products by Product Group/Type - Percentage Breakdown of Value Sales for Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-33

3. JAPAN.............. III-34 A.Market Analysis.............. III-34 Current and Future Analysis..............III-34 Japan Witnesses Surge in Imported Blood Products III-34 Growing Market for Fresh Frozen Plasma III-34 Growing Use of Imported Albumin Based Blood Products III-34 The Goal of Self-Sufficiency III-35 Graying Population to Drive Market Growth III-35 Table 74: Japanese Elderly (65+ Years) Population for the Period 2000-2020 (includes corresponding Graph/Chart) III-36 Corporate Development..............III-36 Select Players.............. III-37 B.Market Analytics..............III-38 Table 75: Japanese Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-38

Table 76: Japanese Historic Review for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-39

Table 77: Japanese 14-Year Perspective for Blood Banking and Blood Products by Product Group/Type - Percentage Breakdown of Value Sales for Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-40

4. EUROPE.............. III-41 A.Market Analysis.............. III-41 Current and Future Analysis..............III-41 Market Trends and Issues..............III-41 Legislations on Payment for Donation Restrict Donors III-41 Government's Check on Healthcare Costs Pressurizes BCT Manufacturers.............. III-41 Purchasing System Witnesses Modifications III-41 Aging Population to Drive Demand for IVIg Products III-42 Table 78: Aging Population in Europe by Geographic Region (2015E & 2020): Percentage of Elderly Individuals of Age 60 Years and Above Compared to Overall Population for Eastern Europe, Northern Europe, Southern Europe, and Western Europe (includes corresponding Graph/Chart) III-42

Table 79: European Market for Intravenous Immunoglobulin by Leading Player (2014): Percentage Market Share Breakdown of Volume Sales by Plasma Fractionators for Baxter Healthcare, Biotest, CSL Behring, Grifols, Kedrion, Octapharma, and Others (includes corresponding Graph/Chart) III-43 Overview of Blood Banking Market III-43 Table 80: European Blood Bag Market (2014E): Percentage Breakdown of Value Sales for Leading Companies - Fresenius/Fenwal, MacoPharma, Terumo and Others (includes corresponding Graph/Chart)..............III-44

Table 81: European Whole Blood Collection Market (2014): Percentage Share Breakdown of Volume Sales for Leading Companies - Fresenius/Fenwal, MacoPharma, Terumo, and Others (includes corresponding Graph/Chart) III-44

Table 82: European Automated Blood Collection Market (2014): Percentage Share Breakdown of Volume Sales for Leading Companies - Fresenius/Fenwal, Haemonetics, Terumo, and Others (includes corresponding Graph/Chart) III-44 B.Market Analytics..............III-45 Table 83: European Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Geographic Region - France, Germany, Italy, UK, Spain, Russia, and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart)..............III-45

Table 84: European Historic Review for Blood Banking and Blood Products by Geographic Region - France, Germany, Italy, UK, Spain, Russia, and Rest of Europe Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart).............. III-46

Table 85: European 14-Year Perspective for Blood Banking and Blood Products by Geographic Region - Percentage Breakdown of Value Sales for France, Germany, Italy, UK, Spain, Russia and Rest of Europe Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-47

Table 86: European Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-48

Table 87: European Historic Review for Blood Banking and Blood Products by Product Group/ Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-49

Table 88: European 14-Year Perspective for Blood Banking and Blood Products by Product Group/Type - Percentage Breakdown of Value Sales for Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-50

4a. FRANCE.............. III-51 A.Market Analysis.............. III-51 Current and Future Analysis..............III-51 Key Players.............. III-51 B.Market Analytics..............III-53 Table 89: French Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-53

Table 90: French Historic Review for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-54

Table 91: French 14-Year Perspective for Blood Banking and Blood Products by Product Group/ Type - Percentage Breakdown of Value Sales for Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-55

4b. GERMANY.............. III-56 A.Market Analysis.............. III-56 Current and Future Analysis..............III-56 Select Players.............. III-56 B.Market Analytics..............III-58 Table 92: German Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-58

Table 93: German Historic Review for Blood Banking and Blood Products by Product Group/ Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-59

Table 94: German 14-Year Perspective for Blood Banking and Blood Products by Product Group/Type - Percentage Breakdown of Value Sales for Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-60

4c. ITALY.............. III-61 A.Market Analysis.............. III-61 Current and Future Analysis..............III-61 Kedrion S.P.A. - A Leading Italian Player for Plasma Fractionation.............. III-61 B.Market Analytics..............III-62 Table 95: Italian Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-62

Table 96: Italian Historic Review for Blood Banking and Blood Products by Product Group/ Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-63

Table 97: Italian 14-Year Perspective for Blood Banking and Blood Products by Product Group/Type - Percentage Breakdown of Value Sales for Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-64

4d. THE UNITED KINGDOM..............III-65 A.Market Analysis.............. III-65 Current and Future Analysis..............III-65 Bio Products Laboratory Ltd - A Leading UK Player for Plasma Fractionation.............. III-65 B.Market Analytics..............III-66 Table 98: UK Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-66

Table 99: UK Historic Review for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-67

Table 100: UK 14-Year Perspective for Blood Banking and Blood Products by Product Group/ Type - Percentage Breakdown of Value Sales for Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-68

4e. SPAIN.............. III-69 A.Market Analysis.............. III-69 Current and Future Analysis..............III-69 Grifols, S.A - A Leading Spanish Player for Plasma Fractionation.............. III-69 B.Market Analytics..............III-71 Table 101: Spanish Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-71

Table 102: Spanish Historic Review for Blood Banking and Blood Products by Product Group/ Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-72

Table 103: Spanish 14-Year Perspective for Blood Banking and Blood Products by Product Group/Type - Percentage Breakdown of Value Sales for Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-73

4f. RUSSIA.............. III-74 Market Analysis.............. III-74 Table 104: Russian Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020(includes corresponding Graph/Chart) III-74

Table 105: Russian Historic Review for Blood Banking and Blood Products by Product Group/ Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-75

Table 106: Russian 14-Year Perspective for Blood Banking and Blood Products by Product Group/Type - Percentage Breakdown of Value Sales for Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-76

4g. REST OF EUROPE.............. III-77 A.Market Analysis.............. III-77 Current and Future Analysis..............III-77 Denmark - High Participation and Consumption of Blood III-77 Strategic Corporate Developments III-77 Select Players.............. III-78 B.Market Analytics..............III-79 Table 107: Rest of Europe Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-79

Table 108: Rest of Europe Historic Review for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-80

Table 109: Rest of Europe 14-Year Perspective for Blood Banking and Blood Products by Product Group/Type - Percentage Breakdown of Value Sales for Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-81

5. ASIA-PACIFIC.............. III-82 A.Market Analysis.............. III-82 Current and Future Analysis..............III-82 Table 110: Asia-Pacific Whole Blood Collection Market (2014E): Percentage Share Breakdown of Volume Sales for Leading Companies - Fresenius/Fenwal, Haemonetics, Weigao, and Others (includes corresponding Graph/Chart) III-82

Table 111: Asia-Pacific Automated Blood Collection Market (2014E): Percentage Share Breakdown of Volume Sales for Leading Companies - Fresenius/Fenwal, Haemonetics, Terumo and Others (includes corresponding Graph/Chart) III-82 ASEAN - Striding Towards Standardization of Blood Supply III-83 B.Market Analytics..............III-83 Table 112: Asia-Pacific Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Geographic Region - China, and Rest of Asia-Pacific Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-83

Table 113: Asia-Pacific Historic Review for Blood Banking and Blood Products by Geographic Region - China, and Rest of Asia-Pacific Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-84

Table 114: Asia-Pacific 14-Year Perspective for Blood Banking and Blood Products by Geographic Region - Percentage Breakdown of Value Sales for China, and Rest of Asia-Pacific Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart).............. III-85

Table 115: Asia-Pacific Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-86

Table 116: Asia-Pacific Historic Review for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-87

Table 117: Asia-Pacific 14-Year Perspective for Blood Banking and Blood Products by Product Group/Type - Percentage Breakdown of Value Sales for Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-88

5a. CHINA.............. III-89 A.Market Analysis.............. III-89 A Key Market.............. III-89 Government Wakes Up to Realities III-89 Table 118: Chinese Market for Blood Banking and Blood Products: Percentage Breakdown of Blood Group by Type - A, B, O, and AB (includes corresponding Graph/Chart) III-90

Table 119: Chinese Market for Blood Banking and Blood Products: Percentage Breakdown of Blood Donor by Gender - Male and Female (includes corresponding Graph/Chart) III-90

Table 120: Chinese Blood Banking and Blood Products Market: Percentage Breakdown of Blood Donor by Age Group - 16-20, 21-30, 31-40, 41-50, 51-60, and 61-70 (includes corresponding Graph/Chart)..............III-90 Overview of Chinese Blood Plasma Market III-91 Table 121: Chinese Blood Products Demand by Type of Product (2014): Percentage Breakdown of Lot Release Volumes for Human IVIG, Human Albumin, Human Rabies Ig, Human Tetanus Ig, and Others (includes corresponding Graph/Chart) III-91 Availability of Plasma Proteins in the US and China (2015): A Comparison.............. III-92 Table 122: Chinese Plasma Based Products Market by Product Type (2015 & 2020P): Percentage Breakdown of Value Sales for Human Albumin, Human IVIg, and Others (includes corresponding Graph/Chart)..............III-93 Government Exercises Strict Control Over Production, Supply and Import of Plasma- based Products III-94 Gap in Domestic Demand and Supply of Plasma Products Persists Despite Increasing Output III-94 Table 123: Plasma Supply, Demand, and Deficit in Chinese Market: 2008-2014 (includes corresponding Graph/Chart) III-95

Table 124: Rising Number of Plasma Collection Stations and Volume of Plasma Collection in China: 2018-2014 (includes corresponding Graph/Chart)..............III-96 Comparison of Average Yields for Select Plasma Based Products in China and International Markets III-96 Deregulation and Supply Crunch to Drive Up Retail Prices of Plasma-based Products..............III-96 Expanding Medical Indications Holds Key to Boosting Market Growth.............. III-97 Comparison of USFDA and CFDA Approved Indications for Human Albumin Therapeutic Products III-97 Comparison of USFDA and CFDA Approved Indications for Human IVIG Therapeutic Products..............III-98 Competitive Landscape..............III-98 Table 125: Chinese Plasma Collection Stations Market by Leading Players (2014): Percentage Breakdown of Stations Owned by China Biologic (CBPO), CNBG Shanghai Institute, Hualan Biological, Shanghai RAAS, and Others (includes corresponding Graph/Chart)..............III-98 Blood Plasma Product Portfolio of Major Domestic Players III-99 Table 126: Chinese Plasma Collection Market by Leading Players (2014): Percentage Volume Breakdown of Plasma Collection for Anhui Tonglu, CBPO, Chengdu Rongsheng, Hualan Biological, Shanxi Kangbao, Sichuan Shuyang, and Others (includes corresponding Graph/Chart) III-100 Albumin Market in China Gains Favor of both Global and Local Players.............. III-100 Table 127: Chinese Human Albumin Products Market by Leading Players (2014): Percentage Breakdown of Volume Sales for Baxter Healthcare, China Biologic (CBPO), CNBG Shanghai Institute, CSL Behring, Grifols International, Octapharma, Shanghai RAAS, and Others (includes corresponding Graph/Chart).............. III-101 Key Statistics.............. III-101 Table 128: Chinese IVIG (Intravenous Immunoglobulin) Products Market by Leading Players (2014): Percentage Breakdown of Volume Sales for China Biologic (CBPO), CNBG Shanghai Institute, Hualan Biological, Shanghai RAAS, and Others (includes corresponding Graph/Chart) III-101

Table 129: Chinese Coagulation Factor VIII Products Market by Leading Players (2014): Percentage Breakdown of Volume Sales for China Biologic (CBPO), Greencross China, Hualan Biological, and Shanghai RAAS (includes corresponding Graph/Chart).............. III-102

Table 130: Chinese Hepatitis B Ig Products Market by Leading Players (2014): Percentage Breakdown of Volume Sales for Anhui Tonrol, China Biologic (CBPO), CNBG Shanghai Institute, Hualan Biological, Hunan Nanyue, Shenzhen Weiwu, Sichuan Yuanda Shuyang, and Others (includes corresponding Graph/Chart) III-102

Table 131: Chinese Rabies Ig Products Market by Leading Players (2014): Percentage Breakdown of Volume Sales for Anhui Tonrol, China Biologic (CBPO), CNBG Shanghai Institute, Guangdong Shuanglin Bio-Pharmacy, Hualan Biological, Hunan Nanyue, Sichuan Yuanda Shuyang Pharmaceutical, and Others (includes corresponding Graph/Chart).............. III-103

Table 132: Chinese Tetanus Ig Products Market by Leading Players (2014): Percentage Breakdown of Volume Sales for Anhui Tonrol, China Biologic (CBPO), CNBG Shanghai Institute, Hualan Biological , Sichuan Yuanda Shuyang Pharmaceutical, and Others (includes corresponding Graph/Chart).............. III-103

Table 133: Chinese Human PCC (Prothrombin Complex Concentrate) Market by Leading Players (2014): Percentage Breakdown of Volume Sales for Hualan Biological, and Others (includes corresponding Graph/Chart) III-104

Table 134: Chinese Human Ig Market by Leading Players (2014): Percentage Breakdown of Volume Sales for China Biologic (CBPO), CNBG Shanghai Institute, Hualan Biological, and Sichuan Yuanda Shuyang Pharmaceutical (includes corresponding Graph/Chart) III-104

Table 135: Chinese Human Fibrinogen Products Market by Leading Players (2014): Percentage Breakdown of Volume Sales for Hualan Biological, Jiangxi Boya Bio-Pharmaceutical, Shanghai RAAS, and Others (includes corresponding Graph/Chart)..............III-105

Table 136: Chinese Plasma Collection Market by Leading Players (2014): Percentage Breakdown of Plasma Collection Volume for Anhui Tonglu, Chengdu Rongsheng Pharmaceutical, China Biologic (CBPO), Hualan Biological, Shanxi Kangbao Biological, Sichuan Yuanda Shuyang Pharmaceutical, and Others (includes corresponding Graph/Chart) III-105

Table 137: Chinese Plasma Market by Leading Players (2014): Percentage Breakdown of Plasma Output Volume for China Biologic (CBPO), CNBG Shanghai Institute, Hualan Biological, Shanghai RAAS, and Others (includes corresponding Graph/Chart)..............III-106

Table 138: Leading Companies in the Chinese Whole Blood Processing Market (2014): Percentage Breakdown of Volume Sales for Fresenius, Shanghai Kindly Enterprise Development Group, Terumo, WEGO and Others (includes corresponding Graph/Chart).............. III-106 Strategic Corpoate Development III-107 Select Key Players..............III-107 B.Market Analytics..............III-109 Table 139: Chinese Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart) III-109

Table 140: Chinese Historic Review for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart)..............III-110

Table 141: Chinese 14-Year Perspective for Blood Banking and Blood Products by Product Group/Type - Percentage Breakdown of Value Sales for Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart) III-111

5b. REST OF ASIA-PACIFIC..............III-112 A.Market Analysis.............. III-112 Current and Future Analysis..............III-112 Overview of Select Regional Markets III-112 Australia.............. III-112 National Blood Supply: An Overview III-112 Role of National Blood Authority III-112 Maintenance Expenditure on the Rise III-112 India.............. III-113 Demand for Blood Banking Equipment Market on the Rise III-113 Recent Trends in the Market..............III-114 Indian Blood Banking Market Witnesses Major Transformations III-114 Market Growth - Influencing Factors III-114 Increased Awareness Drives Voluntary Blood Donations in India III-115 Competitive Scenario..............III-115 Indonesia.............. III-116 Strategic Corporate Developments III-116 Bharat Serums and Vaccines Ltd. - A Leading Indian Player for Plasma Fractionation..............III-117 B.Market Analytics..............III-118 Table 142: Rest of Asia-Pacific Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-118

Table 143: Rest of Asia-Pacific Historic Review for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-119

Table 144: Rest of Asia-Pacific 14-Year Perspective for Blood Banking and Blood Products by Product Group/Type - Percentage Breakdown of Value Sales for Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-120

6. LATIN AMERICA.............. III-121 A.Market Analysis.............. III-121 Current and Future Analysis..............III-121 Table 145: Leading Companies in the Latin American Whole Blood Processing Market (2014): Percentage Breakdown of Volume Sales for Fresenius/Fenwal, Grifols, JP, Terumo and Others (includes corresponding Graph/Chart) III-121 B.Market Analytics..............III-122 Table 146: Latin American Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Geographic Region - Brazil, and Rest of Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-122

Table 147: Latin American Historic Review for Blood Banking and Blood Products by Geographic Region - Brazil, and Rest of Latin America Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes corresponding Graph/Chart) III-123

Table 148: Latin American 14-Year Perspective for Blood Banking and Blood Products by Geographic Region - Percentage Breakdown of Value Sales for Brazil, and Rest of Latin America Markets for Years 2007, 2015 & 2020 (includes corresponding Graph/Chart)..............III-124

Table 149: Latin American Recent Past, Current & Future Analysis for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2014 through 2020 (includes corresponding Graph/Chart).............. III-125

Table 150: Latin American Historic Review for Blood Banking and Blood Products by Product Group/Type - Blood Components and Plasma Products (Whole Blood & Cellular Components, and Plasma Fractions); and Equipment, Blood Tests and Other Consumables Markets Independently Analyzed with Annual Sales Figures in US$ Million for Years 2007 through 2013 (includes correspondin
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